Red Roof Inn Blytheville is located along interstate 55 between St Louis, Missouri and Memphis, Tennessee. Blytheville is in the heart of the Delta and the site of the Arkansas Welcome Center. Enjoy a live show at the Ritz Civic Center or explore the past with exhibits and photos at the Delta Gateway Museum. That Bookstore sponsors book clubs and there are frequent books signing featuring famous authors. Come and experience Blytheville where southern hospitality begins.