You'll Love This Hotel's Location in Columbia, TN Since the Holiday Inn Express® Columbia Hotel is located directly off I-65 at exit 46, we're just a short drive from downtown Columbia and the Nashville Metro area , providing a quick commute for business and leisure travelers. While in Columbia, TN , our hotel's corporate guests can utilize the on-site meeting room for any type of small event, or they can take advantage of the Business Center, which offers computer access and print services. Several businesses, including General Motors , is nearby, and the Maury Regional Medical Center also calls Columbia, TN home. Before you travel to downtown Columbia, stop by the complimentary, hot Express Start Breakfast Bar served each morning. We offer free high-speed, wireless Internet access throughout the facility, as well, so you can stay connected to home and to the office. Call today to take advantage of our great hotel deals and rates!