Search
Best hotels
Best value
When to book
Tips
FAQs
Map

Hotels in Otay Mesa, San Diego

Thu 27/6
Fri 28/6

Search hundreds of travel sites at once for hotels in Otay Mesa

Here is why travellers choose KAYAK

Free to useThere are no hidden charges or fees.

Filter your dealsFilter by free cancellation, free breakfast and more.

Millions of reviewsCheck ratings based on millions of real guest reviews.

Bundle and saveSave money when you bundle your flight + hotel.

Best hotels in Otay Mesa (San Diego)

Most recommended Otay Mesa hotels

Show all
Holiday Inn Express & Suites San Diego Otay Mesa - San Diego - Pool
Free Wi-Fi
Pool
Air conditioning
Quality Suites San Diego Otay Mesa - San Diego - Bedroom
Quality Suites San Diego Otay Mesa
6.8 Okay
Otay Mesa£127+
£127+
Parking
Free Wi-Fi
Pool
Air conditioning

How much is a Otay Mesa hotel?

Here are our most popular & best value hotels

2 stars and below

When to book a hotel in Otay Mesa

Price per night / 3-star hotel. Prices are not fixed and may vary with time.
Average nightly price per month
Average nightly price

Top tips for finding a hotel deal in Otay Mesa

  • For the lowest prices, try to book your Otay Mesa hotel more than 90 days before your stay.
  • Not sure just how much there is to see and do in Otay Mesa? KAYAK users usually book their hotel here for 4 days.

FAQs when booking a hotel in Otay Mesa

  • What are the best hotels in Otay Mesa?

    Otay Mesa is a great part of San Diego to make your base. If you’re staying in Otay Mesa area then Quality Suites San Diego Otay Mesa, Holiday Inn Express & Suites San Diego Otay Mesa, and AAAmazing San Diego! Suite just for you/yours! are all recommended on KAYAK.

  • How much does a hotel in Otay Mesa (San Diego) cost?

    The average price for a hotel room in Otay Mesa is £103 but our users have found deals for as low as £92. However, hotel prices in Otay Mesa vary a lot depending on the type of hotel, the time of year and more factors.

Where to stay in Otay Mesa?

Our map will help you find the perfect hotel in Otay Mesa, San Diego by showing you the exact location of each hotel.