£314 Find Cheap Flights from Manchester to South Carolina – Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Manchester to South Carolina departing on 21/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Manchester to South Carolina

Cheapest return prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops£582
Myrtle Beach
Myrtle Beach2 stops£564
Greenville
Greenville2 stops£588
Columbia
Columbia2 stops£597
Hilton Head Island
Hilton Head Island2 stops£816
Florence
Florence2 stops£939
Charleston
Charleston2 stops£582
Myrtle Beach
Myrtle Beach2 stops£564
Greenville
Greenville2 stops£588
Columbia
Columbia2 stops£597
Hilton Head Island
Hilton Head Island2 stops£816
Florence
Florence2 stops£939

Book Cheap Manchester to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Manchester to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Manchester to South Carolina

Fri, 18 Sep - Sat, 26 Sep
Scandinavian Airlines Logo
19:10 - 20:30
MAN
-
CLT
30h 20m
2 stops
Scandinavian Airlines Logo
14:23 - 18:50
CLT
-
MAN
23h 27m
2 stops
£563Scandinavian Airlines
Thu, 10 Sep - Thu, 17 Sep
Scandinavian Airlines Logo
19:10 - 21:41
MAN
-
MYR
31h 31m
2 stops
Scandinavian Airlines Logo
14:20 - 18:30
MYR
-
MAN
23h 10m
2 stops
£564Scandinavian Airlines
Thu, 27 Aug - Thu, 3 Sep
Multiple Airlines Logo
08:10 - 19:05
MAN
-
GSP
15h 55m
2 stops
Multiple Airlines Logo
11:25 - 20:25
GSP
-
MAN
28h 00m
2 stops
£692Multiple Airlines
Wed, 26 Aug - Wed, 2 Sep
Multiple Airlines Logo
08:10 - 19:05
MAN
-
GSP
15h 55m
2 stops
Multiple Airlines Logo
11:25 - 13:55
GSP
-
MAN
21h 30m
2 stops
£692Multiple Airlines
Tue, 8 Sep - Wed, 30 Sep
British Airways Logo
07:55 - 20:59
MAN
-
MYR
18h 04m
2 stops
British Airways Logo
12:52 - 09:50
MYR
-
MAN
15h 58m
2 stops
£747British Airways
Tue, 8 Sep - Wed, 30 Sep
Virgin Atlantic Logo
13:00 - 21:41
MAN
-
MYR
13h 41m
1 stop
Virgin Atlantic Logo
18:58 - 08:50
MYR
-
MAN
32h 52m
1 stop
£773Virgin Atlantic
Tue, 8 Sep - Wed, 30 Sep
Virgin Atlantic Logo
13:00 - 21:41
MAN
-
MYR
13h 41m
1 stop
Virgin Atlantic Logo
18:58 - 20:05
MYR
-
MAN
20h 07m
2 stops
£773Virgin Atlantic
Tue, 15 Sep - Mon, 30 Nov
British Airways Logo
06:55 - 23:59
MAN
-
SAV
22h 04m
2 stops
British Airways Logo
10:30 - 09:50
SAV
-
MAN
18h 20m
2 stops
£775British Airways
Mon, 23 Nov - Sun, 29 Nov
Aer Lingus Logo
08:05 - 20:49
MAN
-
CLT
17h 44m
2 stops
Aer Lingus Logo
06:00 - 09:30
CLT
-
MAN
22h 30m
2 stops
£791Aer Lingus
Fri, 20 Nov - Tue, 24 Nov
Aer Lingus Logo
08:05 - 20:49
MAN
-
CLT
17h 44m
2 stops
Aer Lingus Logo
07:40 - 09:30
CLT
-
MAN
20h 50m
2 stops
£799Aer Lingus
Booking Insights

KAYAK's insights & trends for Manchester to South Carolina flights

Get data-powered insights and trends into flights from Manchester to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a return flight from Manchester to South Carolina?

This analysis is based on the cheapest return trip price found on KAYAK in the last 12 months by searching for a flight from Manchester to South Carolina departing in September.

Flight prices are below average for this route right now.

Flights to South Carolina from Manchester usually cost between £633 and £1,208 in September.
The lowest price found in the past 5 days was £582 on Scandinavian Airlines (12 Sept–19 Sept).

What is the cheapest month to fly from Manchester to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Manchester to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Manchester to South Carolina is January, when tickets cost £630 (return) on average. On the other hand, the most expensive months are July and December, when the average cost of return tickets is £1,011 and £870 respectively.

Good to know - Cheap tickets from Manchester to South Carolina

Low season

February

Cheapest flight

£314
Best time to beat the crowds (6% less expensive on average)
Most popular time to fly and prices are also 19% lower on average.
Flight from Manchester to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Manchester to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Manchester to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Manchester to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Manchester to South Carolina is likely to change within 7 days, so travellers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Manchester to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly from Manchester to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Manchester to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Manchester to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines flying from Manchester to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Manchester to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Manchester to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
KLMOverall score based on 1552 reviews
8.4Crew
7.3Food
7.7Comfort
7.8Boarding
7.2Entertainment
Airline reviews

The flight was 45 mins late leaving, we sat without a/c for some of this, 2nd Meal was a slice of pizza. Movies were good.

8.0 ExcellentAnonymous, Jun 2026
LHR - AMS
Read more KLM reviews

The flight was 45 mins late leaving, we sat without a/c for some of this, 2nd Meal was a slice of pizza. Movies were good.

Short flight so it was okay. Nice crew, all very pleasant and professional. We were near the back in row 27 so just as we got our drinks, we started our descent so had to drink very quickly!

The flight was great, the only reason for middle scores on entertainment and food is that it was a short flight so not included (but snacks were served including alcoholic beverages free of charge). I would definitely recommend KLM.

Was trying to change a flight but told that Canadian and local klm systems do not interact so they could not access my booking. Overall I like klm a lot but if it was important to change flights I would be very frustrated.

KLM is my favourite airline. Never ever let us down.Staff are first class.

Pretty bad. Food was awful. drinks were scarce, as if drinking an extra drink would ruin the airline. attendants were not very helpful. likely Dutch "directedness" (I cannot be bothered). Crammed flight. Entertainment in very minimal dosage. Almost all old movies and series with 1-3 episodes only. Very limited number of options available. Jesus!! it seems you need to bring your own entertainment these days even of flights that are 13 hrs long!! I would and I will avoid in the future!

I travel frequently. The flight was late again... KLM should really try and be on time

The flight itself it was great nice food the crew were very nice and helpful, Checking in from Birmingham wasn't great long queues for bag dropped, And I had my hand luggage case taken away from me even though I requested to have it with me as I had breakables items. I was told I can not because of the length of the flight with no explanation at all no options was given for me to take my fragile items out of my case it was taken away with hold buggage I find the staff member who was checking me in very unpleasant !! Can we please be advise if the rules have changed about the the carry on hand luggage it will be easier to be advise on booking your tickect if we not allowed to take the hand luggage with me. Overall I had a good flight .

I requested wheel chair assistance , it was confirmed via email that inwoood get it but I didn’t get it . The last leg of my trip to Nigeria was the worst.

Boarding in NCL is really bad. I'm sure part of that is a directive from the airport that KLM can't change but part of that is due to KLM policy. NCL doesn't announce the gate of departure until 30 minutes before departure. However, when you arrive at the gate area, the gate agents file everyone into one long line and everyone boards from one line at one time. This line can stretch for 200m...easily. There is a separate line for groups 1 and 2 but you don't know it until you get to the gate area and agents don't announce/advertise it. Everyone else is grouped into one line. Are you in group 3? Doesn't matter...you board with group 5. Traveling with a child? Tough luck...you're stuck at the end of the line and board last. The last part is very annoying because none of the gates at NCL (with the exception of 1 used by Emirates) has a jetway. To board, you must leave the gate area, walk downstairs, walk onto the tarmac and walk up stairs to board the plane. Highly challenging if you're traveling with small children. That boarding process begs for a concession to allow people with children to board first because they will need extra time. But there is no such policy. Just a really horrible boarding experience all around.

London to Atlanta was good. Atlanta to Phoenix was not. Poor boarding as I had to check my rollerboard even though there was plenty of room in the bins. Crew seemed inexperienced. Sat just off the gate for nearly 30 minutes with no explanation from the pilot while the cabin got hot. I typically have a much better experience with Delta.

Wonderful crew, great movie selection and good food. I prefer Airbus to Boeing, much more comfortable

I wish the inflight entertainment system options were broader, but overall this was a fantastic crew and I can’t express how cheerful, welcoming, and attentive they were.

Flight was operated by Virgin Atlantic and it was up to their usual high standard. Minor grips about some issues, but they are really first world issues and as a whole, was an excellent flight.

I paid for a business class ticket on Delta. It was sourced to Virgin Atlantic. They changed out the aircraft which had fewer upper class tickets. Even though I'd checked into the lounge, was receiving alerts via kayak about the delay and changes; no one informed me that the seat would be changed - until I attempted to board and was told that I would have an economy seat or they could search to put me on another airline. Even the flight crew were informed of this change (10 passengers were bumped out of Upper Class) around 2 pm (1400) time. Hours would have helped to consider alternatives instead of making a last minute change. There needs to be compensation from both Delta and Virgin given this change in service/experience.

Movie selection was meh. Food was great. Crew as always great. I paid for premium because that’s the only way not to feel like a sardine. That’s how economy should be imo. Sadly passengers have to pay an extra $1000 to get what they should at base price but that’s all airlines. The airline industry in general treats passengers as cargo.

Ongoing flight was delayed. Staff at bag recheck was able to get us on an earlier flight. With only 20 minutes till take off we feared our bags would not make the new earlier flight. We were most delighted that they did and were there when we landed. Delta came through

When checking our bags at the Virgin Atlantic counter, the employee told us that we should go to Delta because we needed to verify our passports and our names. Fortunately the employee organizing the line stopped us and asked why we didn't hand over our suitcases. He sent us to another line and told the employee that we already have the passports verified in the reservation. She understood and received our suitcases. In London they have a general waiting room, where you stay until the gate number of your flight is announced. KAYAK informed us the gate number hours before the airlines did. Just like the flight to London, the legroom is too small. abusive for a flight of so many hours.

Bathroom broke, had to rush to board because of late exit of previous flight

W were seated in the middle of 4-seat row so we had to bother other passengers to get out. Seats were packed together too tightly. It was a very uncomfortable place to sit for 8 hours.

Lounge was top notch h with great variety of food and drinks. Cabin crew were great. Smooth flight.

My seat 3G did not go down fully and the buttons were not working properly

Food was the worst I’ve had on a VA flight. Normally it’s a lot better

The staff was not very polite but the flight was very very nice and comfortable and the entertainment was great

Security area in terminal 3 needs to be made much nicer. Less claustrophobic and use of glass and big ceilings wouldhelp

accomodating check in staff, friendly flight crew ( a crew member was speaking tactlessly and was overfamiliar with passengers

Seats need to be updated. Allowance needs to be made for dinner service at an alternative time

The crew should demonstrate flexibility by moving a screaming infant to its own seat with 1 parent

If I could fly Virgin Atlantic airlines to every place, I need to go, I would. Leaving Heathrow through the special virgin air entrance, security is completely white glove service. I love this airline. From ticketing agents to flight staff everyone tries to make it a wonderful & happy flight experience. I wish other airlines copied the positive culture of Virgin Airlines.

The crew on both flights were courteous and professional. The flights were smooth and on time. Great experience overall. There could have been at least a drink on the flight's JFK - JAX leg.

Plane features were VERY old and outdated. footrest cushion was completely lose, plane felt dirty and a bit grimy. i was in business class. the lead flight attendant, Mary made a few announcements that didn't seem to put the cabin at ease (it didn't necessarily bother me, but could have bothered others). she said "the seat cushions aren't FDA approved, so you have to put them on after we take flight." everyone had already applied the seat cushions, and saying something isn't approved for flight may cause alarm. she also said at one point over the announcement ... "we can't get up because we are too afraid of the jet stream impacts" -- again, not helpful to those who are nervous fliers.

Extremely comfortable airplane, everything looked brand new, how lovely! My seat in Premium Economy was ever so comfortable, I did not suffer the usual backache I suffer when doing the transatlantic flight. It felt like seating in a reclining armchair. I loved the foot rest, did not need to use the portable device I usually carry along with me to replace one. I loved the spaciousness in front of me, and that there were only two seats (Instead of 3 in coach) in the window row, wow what a difference in comfort. Coach seats are always just a little narrow for my hips. The support of the cushions was great, firm and offered good support . It was easy to come out of my aisle seat, although I'm 70. The staff was courteous, both meals were delicious, very carefully prepared, and creative (fruit + cheese for the second meal, instead of the usual bread sandwich)

The plane was up-to-date, and the free wi-fi was very much appreciated! All of the ports functioned well, and the entertainment choices made the flight much more enjoyable. One of the flight attendants was unfriendly, but the flight was enjoyable overall.

3 hour delay before takeoff & another 30 minutes on the plane before taxi to runway

Rudest flight attendants ever, waited over 20 for light to be answered and it never was then tried to flag down an attendant who said someone else would come, just needed water to take some medicine Food bad

My entertainment unit kept locking up and had to be restarted multiple times. Also those commercials for Budapest and Ralph Laureen. Come on those were stuff only those who can afford the outrageous fees of first and business class would be interested in.. And the fact you have no military discount is not good either,

I was a Wheelchair Assist’ passenger on a London Heathrow to PHL flight yesterday. The process of getting me and my carry-on bag from the ticket counter to the gate was not good at all. It was the worst in my 5 years of experience using this service offered by American. The Philadelphia ‘Wheelchair Assist’ service was, and always has been Excellent! Not so at Heathrow. I was handed off to three different wheelchair drivers; had to sit in a very dingy holding area for 30 minutes while waiting for our gate change announcement; got crammed into a overloaded service vehicle to take me from the holding area to the gate ; was dumped at the end of the line of already-boarding passengers with my heavy carryon and no one helped me up the ramp way at the gate to board the plane. Overall it was a miserable experience!

Crew was nice, aircraft dated, entertainment same. Internet is expensive and terribly slow. Food pretty bad

Horrible experience. Food was ridiculous, insufficient, and not appetizing at all. They served sugary granola bar for breakfast. Furthermore, my bags were delayed and delivered damaged and American made it impossible to file for damages. Furthermore, the flights were delayed causing unnecessary stress given the connecting flights. It was awful experience, would never want to fly American.

My table was broken so it made it difficult to eat the food during the service. I was also informed that my luggage did not make it with me to Phoenix. I live two hours away so this makes it even more stressful to try and arrange a time for pick up

Really appreciated the care, attention and friendliness of cabin crew. Very comfortable, prompt and efficient flight.

The space in the seat was okay, the staff were friendly, the entertainment system, my touch screen was not working and some of the films listed on the website for the flight were not available.

Big queues on arrival at airport despite having already checked in and only needed to drop bags off. Flight delayed which impacted on connecting flight.

The check-in baggage belt was broken (which is understandable) but what was surprising is they would check you in, give a baggage tag and then you have to drag the baggage to a different counter at the end of airport. No vegetarian option in in-flight meal. British Airways remains the worst big name airlines and always my last option while booking.

Very bad.i will never book British flights for future

Smooth roundtrip to Manchester, UK from SFO. I think BA is fabulous.

Both the flight from/to San Diego and London went very well. There were lots of movies from which to choose for entertainment, the food was nice, and the flight departure and landing times were good to minimize jet lag.

Very quiet aircraft, business class was spacious and comfortable. Very pleased with the service.

The worst travel experience of my life. Boarding chaos, delays and disorganisation at every stage. The worst of many was sitting in freezing temperatures for 10 hours whilst asking all cabin crew to turn the heat up to no avail.

It was a flight operated by Aer Linus for BA and the plane and crew were very good but the food selection was average.

Everything you need to know for your flight from Manchester to South Carolina

Information on your arrival and departure airports