£341 Find Cheap Flights from Manchester to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Manchester to South Carolina departing on 16/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Manchester to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Manchester to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Manchester to South Carolina

Cheapest return prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops£710
Myrtle Beach
Myrtle Beach2 stops£748
Greenville
Greenville2 stops£762
Columbia
Columbia2 stops£761
Hilton Head Island
Hilton Head Island2 stops£796
Florence
Florence2 stops£1,069
Charleston
Charleston2 stops£710
Myrtle Beach
Myrtle Beach2 stops£748
Greenville
Greenville2 stops£762
Columbia
Columbia2 stops£761
Hilton Head Island
Hilton Head Island2 stops£796
Florence
Florence2 stops£1,069

Book Cheap Manchester to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Manchester to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Manchester to South Carolina

Thu, 10 Sep - Sun, 13 Sep
Multiple Airlines Logo
08:10 - 23:59
MAN
-
CHS
20h 49m
2 stops
Multiple Airlines Logo
15:15 - 13:55
CHS
-
MAN
17h 40m
2 stops
£710Multiple Airlines
Mon, 12 Oct - Mon, 19 Oct
British Airways Logo
06:55 - 19:12
MAN
-
CHS
17h 17m
2 stops
British Airways Logo
13:12 - 13:10
CHS
-
MAN
18h 58m
2 stops
£730British Airways
Mon, 21 Sep - Mon, 28 Sep
Scandinavian Airlines Logo
09:35 - 22:44
MAN
-
CLT
18h 09m
2 stops
Scandinavian Airlines Logo
14:15 - 18:30
CLT
-
MAN
23h 15m
2 stops
£733Scandinavian Airlines
Thu, 10 Sep - Sat, 19 Sep
Scandinavian Airlines Logo
09:35 - 22:23
MAN
-
CLT
17h 48m
2 stops
Scandinavian Airlines Logo
07:15 - 08:55
CLT
-
MAN
20h 40m
2 stops
£733Scandinavian Airlines
Mon, 12 Oct - Mon, 19 Oct
Virgin Atlantic Logo
13:00 - 20:41
MAN
-
CHS
12h 41m
1 stop
Virgin Atlantic Logo
14:25 - 08:50
CHS
-
MAN
13h 25m
1 stop
£792Virgin Atlantic
Mon, 12 Oct - Mon, 19 Oct
Virgin Atlantic Logo
11:00 - 22:11
MAN
-
CHS
16h 11m
2 stops
Virgin Atlantic Logo
12:45 - 08:15
CHS
-
MAN
14h 30m
1 stop
£794Virgin Atlantic
Mon, 13 Jul - Mon, 20 Jul
American Airlines Logo
08:00 - 20:32
MAN
-
SAV
17h 32m
2 stops
American Airlines Logo
17:56 - 15:10
SAV
-
MAN
16h 14m
2 stops
£807American Airlines
Sat, 27 Jun - Tue, 30 Jun
American Airlines Logo
07:45 - 21:59
MAN
-
CAE
19h 14m
2 stops
American Airlines Logo
18:03 - 13:05
CAE
-
MAN
14h 02m
2 stops
£837American Airlines
Mon, 26 Oct - Sun, 1 Nov
Delta Logo
13:00 - 10:37
MAN
-
SAV
25h 37m
1 stop
Delta Logo
18:50 - 16:05
SAV
-
MAN
16h 15m
2 stops
£864Delta
Sat, 27 Jun - Sat, 4 Jul
Delta Logo
13:15 - 21:07
MAN
-
SAV
12h 52m
1 stop
Delta Logo
17:36 - 16:55
SAV
-
MAN
18h 19m
2 stops
£906Delta
Booking Insights

KAYAK's insights & trends for Manchester to South Carolina flights

Get data-powered insights and trends into flights from Manchester to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a return flight from Manchester to South Carolina?

This analysis is based on the cheapest return trip price found on KAYAK in the last 12 months by searching for a flight from Manchester to South Carolina departing in September.

What is the cheapest month to fly from Manchester to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Manchester to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Manchester to South Carolina is June, when tickets cost £458 (return) on average. On the other hand, the most expensive months are July and May, when the average cost of return tickets is £752 and £570 respectively.

Good to know - Cheap tickets from Manchester to South Carolina

Low seasonFebruary
Cheapest flight£341
Best time to beat the crowds (6% less expensive on average)
Most popular time to fly and prices are also 17% lower on average.
Flight from Manchester to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Manchester to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Manchester to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Manchester to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Manchester to South Carolina is likely to change within 7 days, so travellers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Manchester to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly from Manchester to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Manchester to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Manchester to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines flying from Manchester to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Manchester to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Manchester to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8398 reviews
8.5Crew
7.2Food
7.8Comfort
8.1Boarding
7.8Entertainment
Airline reviews

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

10.0 ExcellentJOSEPH, Jun 2026
RIC - ATL
Read more Delta reviews

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

Original flight was delayed, then cancelled and the gate staff did not expedite rebooking. Also, no instructions were given that a ticket number was needed before being called to facilitate rebooking. This could have been much more organized.

Be on time? When not on time a circling for over an hour offer more than 1 bag of chips to the passengers? It was a 7 hour flight by the time we got done.

Five hour delays every hour, I wish it were all at once

Flight delayed four separate times. I’m now one hour hours late to landing.

worst flight ever from Delta, it got delayed and kept on delaying..

Should never have had to go to Detroit from Orlando back to Tennessee!

Got rerouted from a straight flight from Orlando to Atlanta to Knoxville to a flight from Orlando to Detroit to Knoxville! Seriously!! Flight delay out of Detroit! Long day for what should have been a pretty easy travel day!

Two delays on two separate planes with parts they could not easily find and replace.

The flight was 45 mins late leaving, we sat without a/c for some of this, 2nd Meal was a slice of pizza. Movies were good.

There were no charge points for phones on the economy seats. The seats were comfortable overall. Food was okay.. flight was on time

It was really nice experience by flying this klm flight.I personally recommend everyone to please try this klm flight

Crew is not the cheerful type. very slow meal service (this is their style as have flown this many times)

Empty seats next to me - wish it had been for a longer flight!!

At the airport, terrible, I do not want to even remember it. It was too humiliating for a business class passenger.

Flight was ok but lack of communication cost me to literally beg to be put on another flight as connecting flight had departed

Couldn’t get boarding pass in SLC even with help from a redcoat, so had to find a desk in AMS to get boarding pass. Technical problems so not sure why. Very inconvenient. The KLM app is not as user friendly as most apps. Also had to wait almost an hour on the tarmac for a fuel truck, which caused us to miss a connecting bus in LUX.

The immigration hall in Amsterdam was understaffed, so passport checking was slower than it should be for a major airport. They need to get the automatic readers up and running for non EU passport holders. Waiting in line after a long flight feels a bit abusive.

Over 1 Hr delay. No APU so no AC on ground. Plane was hot during boarding and then they closed the doors over 20 minutes before engine start so interior of plane was steamy hot and stuffy. Could have been helped by opening doors until ready to depart.

Lounge was top notch h with great variety of food and drinks. Cabin crew were great. Smooth flight.

Seating and zone. The minor I went with didn’t even seat close to me

My seat 3G did not go down fully and the buttons were not working properly

Food has been disappointing in both legs of flight to india

Great staff great experience, made a 2 hour delay very bearable

Great staff, great experience, made a 2 hour delay very bearable

Food was the worst I’ve had on a VA flight. Normally it’s a lot better

I was my pleasure to fly virgin on my birthday for my first solo trip ever 🫶🏼

These are one of the older seat arrangements facing away from the windows! Not particularly convenient sets. No storage spaces. NO COAT HANGING HOOKS. Inconvenient business class seat compared to any other airlines of similar class. Staff are excellent! Extremely professional, friendly. Food is good too.

Overall, flight was excellent but check in was very slow for Premium Economy. Economy queue was shorter but we weren't allowed to use it.

Crew was nice, aircraft dated, entertainment same. Internet is expensive and terribly slow. Food pretty bad

Horrible experience. Food was ridiculous, insufficient, and not appetizing at all. They served sugary granola bar for breakfast. Furthermore, my bags were delayed and delivered damaged and American made it impossible to file for damages. Furthermore, the flights were delayed causing unnecessary stress given the connecting flights. It was awful experience, would never want to fly American.

My table was broken so it made it difficult to eat the food during the service. I was also informed that my luggage did not make it with me to Phoenix. I live two hours away so this makes it even more stressful to try and arrange a time for pick up

Very hard to beat a British Airways international flight…the crews are always so amazing! One flight attendant that really stood out was Emma…she was very personable and accommodating with any request we had!!

The passport line was so long that many of us were concerned about missing our flight and some did. It would've helped if a AA representative had gone to the passport check-in sooner to advise that boarding was closing and those flying that were stuck back in the line, needed to come forward with apologies to others. An AA representative did do that but only after boarding had already closed. (They delayed take-off so that more who were running with carry-ons could get to the gate - especially stressful for older people!) Then to be crammed into a seat with barely enough leg room for a thin woman, 5'7", like me, much less for a taller, bigger person was not comfortable, especially if the person in front decided to lean back. Crew was fine, food and entertainment also.

The seat when "flat" was not flat and pad was too thin to cover it.

Awful customer service, horrible experience. We travel a lot domestic & international- worst flights to/from ever. Brief bkgd as Inhate to relive this experience: booked and chose 2 seats 4 months prior in Premium Economy - last row end seats close to bathroom, no one behind us, plenty of legroom;, underwear storage — flown this was on other airlines, love it. We receive notice 4 days before scheduled overseas flight - plane has changed, new seats assigned. Seats are split into single seats, opposites of the plane, FRONT Row so no reachable storage. Called BOTH British Air & America. American “switched planes and the seats you want are taken;” British Air “Yes, we’ll be glad to accommodate you (type type type). Just ask at the Gate and someone will give you new boarding passes with seats together in middle, OK?” — OK. —At Gate the attendant looks us up saying “No, it is an overbooked flight and yours are the only seats available.” But but but wait, “We were TOLD our seats had been switched and seated together?” Gate attendant “Well they were wrong and don’t change your seats. Your original seats are where you’ll sit.”. Right. No help WHATSOEVER. We sit opposite on way there, wife VERY disgruntled, a Tol 5 worst ways to start a 3-week bus tour of UK. We promise to NEVER FLY AMERICAN OR BROTISH AIR EVER, and we have 3 more extensive trips planned..

They lost my bag. ... And I asked them 3 times to 3 different people if my checked bag will maKe it all the way - they all confirmed and at the end it was left at the connection... Bravo

British Airways is an excellent airline. Comfort, food and airline personnel.

Older airplane with worn out seats. No entertainment system at all. Connecting to Wi-Fi was problematic and hit and miss.

Seats not as comfortable as I had hoped. Food was very nice, service was fine. Entertainment options very nice. Had thought the premium economy was a more plus 2-3-2 layout but it was a 2-4-2 with seats not as wide as I had expected.

I flew four flights on British Airways within two weeks. I was unable to download the boarding pass to my phone for any of the four flights. I could check-in for my flight but the system would not give me boarding pass. I tried multiple ways and multiple times. I discovered many other passengers also had the same issue with their boarding passes. No explanation or acknowledgement by BA.

Lovely big plane. Excellent take off and landing. Cabin crew were so nice. Flight in time no delays

Because our ABZ-LHR flight was cancelled by BA for reasons they refuse to tell us--not weather--we did not make this flight and were booked on the following day. BA offered no assistance to us on the phone or in the airport, and we had to find a hotel at Heathrow on our own.

Horrible - flight was delayed by 6 hours - we boarded, were made to de-board due some technical fault; aircraft changed; special meals request on new flight - all went awry. Landed in Dulles airport; breezed thru immigration; as Business Class passengers or baggage was delivered almost 90 minutes after landing; air tags indicated the bags were just near the carousel but the unhelpful BA staff - Maria and Ghina refused to give any update - palming it off on some imaginary invisible “manager” despite air tags evidence showing it right there. So about 50-60 passengers waiting and getting infuriatingly impatient for their bags coz one container was not delivered. Finally after much argument by some other passengers Maria condescended to go to the “ramp” and within 5 minutes the baggage was delivered miraculously. Question is why couldn’t she have done it one hour earlier ? Poor poor experience once again on Business Class BA.

Cheap Flight Fares would not provide booking info. I canceled the reservation and we arbitrated with American Express. They provided erroneous info to Amex and it was determined that C.F.F. deserved the price of the ticket. Worse experience I've ever had.

Seating space is appalling. Seats and all surrounding area in "Economy" is built for individuals shorter than 4' 10" and below 120 lbs. Ridiculous. While I'm not expecting fine dining, the food was the worst airplane food that I can recall.

Business class lounge for my gate was closed and no email was sent, causing me to walk back and forth to different gates, etc for over 20 minutes one way. Flight entertainment was mediocre with very poor choices especially for business class cabin. Original flight was cancelled and rebooking was difficult and no reason given for cancellation.

Very comfortable flight and simple and directed one way and back. Amazing price.

We loved our flight attendant, Emma from Scotland, the meal and entertainment offerings were wonderful, the flight was smooth, and enough leg room to stretch. We would fly with you again!

Everything you need to know for your flight from Manchester to South Carolina

Information on your arrival and departure airports