MAD - VVI

£361 Find Cheap Flights from Madrid to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 30/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Madrid to Santa Cruz de la Sierra (MAD-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Madrid to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Madrid to Santa Cruz de la Sierra

Wed, 19 Nov - Sat, 6 Dec
LATAM Airlines Logo
00:40 - 04:35MAD-VVI
32h 55m1 stop
LATAM Airlines Logo
05:25 - 16:25VVI-MAD
30h 00m1 stop
£681LATAM Airlines
Find Deal
Tue, 10 Feb - Mon, 9 Mar
Avianca Logo
06:35 - 02:35MAD-VVI
25h 00m1 stop
Avianca Logo
03:40 - 13:25VVI-MAD
28h 45m1 stop
£723Avianca
Find Deal
Wed, 19 Nov - Thu, 4 Dec
Multiple Airlines Logo
00:40 - 04:35MAD-VVI
32h 55m1 stop
Multiple Airlines Logo
13:30 - 05:10VVI-MAD
10h 40mdirect
£734Multiple Airlines
Find Deal
Thu, 20 Nov - Fri, 5 Dec
LATAM Airlines Logo
00:40 - 04:35MAD-VVI
32h 55m1 stop
LATAM Airlines Logo
05:25 - 16:25VVI-MAD
30h 00m1 stop
£751LATAM Airlines
Find Deal
Mon, 24 Nov - Sun, 7 Dec
Iberia Logo
13:45 - 19:45MAD-VVI
11h 00mdirect
Iberia Logo
19:30 - 11:20VVI-MAD
10h 50mdirect
£769Iberia
Find Deal
Wed, 19 Nov - Tue, 2 Dec
Multiple Airlines Logo
00:40 - 04:35MAD-VVI
32h 55m1 stop
Multiple Airlines Logo
13:30 - 05:10VVI-MAD
10h 40mdirect
£772Multiple Airlines
Find Deal
Sun, 23 Nov - Sat, 6 Dec
United Airlines Logo
11:05 - 03:36MAD-VVI
45h 31m2 stops
United Airlines Logo
11:40 - 08:05VVI-MAD
39h 25m2 stops
£812United Airlines
Find Deal
Fri, 21 Nov - Thu, 4 Dec
Air Europa Logo
03:05 - 09:25MAD-VVI
11h 20mdirect
Air Europa Logo
13:30 - 05:10VVI-MAD
10h 40mdirect
£814Air Europa
Find Deal
Mon, 24 Nov - Mon, 1 Dec
United Airlines Logo
11:05 - 22:46MAD-VVI
40h 41m2 stops
United Airlines Logo
11:40 - 08:05VVI-MAD
39h 25m2 stops
£815United Airlines
Find Deal
Fri, 21 Nov - Sat, 6 Dec
Air Europa Logo
03:05 - 09:25MAD-VVI
11h 20mdirect
Air Europa Logo
13:30 - 05:10VVI-MAD
10h 40mdirect
£850Air Europa
Find Deal

Everything you should know

Our travellers' advice
AI-generated summary based on content written by travel experts
Air Europa offers speedy Wi-Fi for all needs.
Iberia serves Spanish cuisine with two meals onboard.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
LATAM Airlines
Cheapest • from £681 (return)
Iberia
Best reviews • 7.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travellers who book at least 3 weeks in advance save around 20% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 25% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Direct flights
5 days a week
There are direct flights from Madrid to Santa Cruz de la Sierra 5 days a week: Mon, Wed, Fri, Sat, Sun.
Direct flights
Direct flights
Direct flights
Direct flights
Cheapest return fare
£681
Typical prices: £784-£1,090
LATAM Airlines
Wed 19/11Sat 6/12
MAD - VVI • 1 stop
Cheapest direct flights
£769
Typical prices: £797-£1,182
Iberia
Mon 24/11Sun 7/12
MAD - VVI • Direct
Start a new search
KAYAK searches hundreds of sites at once to find you the best travel deals.
We hope you love your trip to Santa Cruz de la Sierra!
Booking Insights

KAYAK's insights & trends for Madrid to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Madrid to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

How much is a return flight from Madrid to Santa Cruz de la Sierra?

This analysis is based on the cheapest return trip price found on KAYAK in the last 12 months by searching for a flight from Madrid to Santa Cruz de la Sierra departing in November.

What’s the cheapest day of the week to fly from Madrid to Santa Cruz de la Sierra?

The average price of all round-trip flights from Madrid to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Santa Cruz de la Sierra on a Friday and more expensive on a Saturday. On your return trip to Madrid, you should consider flying back on a Monday, and avoid Tuesdays for better deals.

What is the cheapest month to fly from Madrid to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Santa Cruz de la Sierra is May, where tickets cost £602 (return) on average. On the other hand, the most expensive months are December and August, where the average cost of round-trip tickets is £1,082 and £1,053 respectively.

Can I save money by flying with a stopover from Madrid to Santa Cruz de la Sierra?

The average return price for all direct flights, flights with one stopover, and flights with two stopovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a stopover may cost you more time, but you can also save money on the route, with a 1 stop stopover the cheapest option at £827 on average.

How far in advance should I book a flight from Madrid to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Santa Cruz de la Sierra, you should book around 3 weeks before departure, which saves you about 20% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Santa Cruz de la Sierra

 
Snippets provided in this section are AI-generated based on a summarisation of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers speedy Wi-Fi with packages for all needs during your flight.


Air Europa provides special meals including diabetic, gluten-free, and vegan options on transatlantic flights.

Iberia

Iberia’s Business class offers roomy seating with all-aisle access and comfortable bedding.


Enjoy Spanish cuisine with two meals and a variety of beverages on long-haul flights.

Read more about Iberiaby Marisa Garcia
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Read more

Good to know - Cheap tickets from Madrid to Santa Cruz de la Sierra

Low seasonApril
Cheapest flight£361
Best time to beat the crowds (16% less expensive on average)
Most popular time to fly (35% more expensive on average)
Flight from Madrid to Santa Cruz de la Sierra

When to book flights from Madrid to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Madrid to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santa Cruz de la Sierra

  • What is the cheapest flight from Madrid to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Madrid to Santa Cruz de la Sierra was £361 for a one-way ticket and £681 for a return.

  • Which airports will I be using when flying from Madrid to Santa Cruz de la Sierra?

    Madrid and Santa Cruz de la Sierra are both served by 1 main airport. You will leave Madrid from Madrid Barajas and will be arriving at Santa Cruz de la Sierra Viru Viru Intl.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santa Cruz de la Sierra?

    Iberia, Lufthansa, Vueling, and Qatar Airways offer inflight Wi-Fi service on the Madrid to Santa Cruz de la Sierra flight route.

  • Which aircraft models fly most regularly from Madrid to Santa Cruz de la Sierra?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Madrid to Santa Cruz de la Sierra flight route.

  • Which airline alliances offer flights from Madrid to Santa Cruz de la Sierra?

    oneworld, and Star Alliance are the airline alliances operating flights between Madrid and Santa Cruz de la Sierra, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Santa Cruz de la Sierra?

    You can catch a direct flight from Madrid to Santa Cruz de la Sierra on on Monday, Wednesday, Friday, Saturday, and Sunday.

  • Which is the best airline for flights from Madrid to Santa Cruz de la Sierra, Iberia or BoA?

    The two airlines most popular with KAYAK users for flights from Madrid to Santa Cruz de la Sierra are Iberia and BoA. With an average price for the route of £612 and an overall rating of 7.0, Iberia is the most popular choice. BoA is also a great choice for the route, with an average price of £689 and an overall rating of 6.7.

  • How does KAYAK find such low prices on flights from Madrid to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Madrid with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Madrid to Santa Cruz de la Sierra?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl.
Find which airlines fly direct from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl

Monday

Air Europa, BoA

Air Europa, BoA

Wednesday

Air Europa, BoA

Air Europa, BoA

Friday

BoA

BoA

Saturday

Air Europa

Air Europa

Sunday

BoA, Air Europa

BoA, Air Europa

See more direct flights

Direct returns

Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas

Monday

BoA, Air Europa

BoA, Air Europa

Tuesday

Air Europa, BoA

Air Europa, BoA

Thursday

Air Europa, BoA

Air Europa, BoA

Saturday

Air Europa, BoA

Air Europa, BoA

Sunday

BoA

BoA

See more direct flights

Reviews of the top 3 airlines flying from Madrid to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
IberiaOverall score based on 3001 reviews
7.1Boarding
6.6Entertainment
7.7Crew
6.7Comfort
6.3Food
Airline reviews

We flew into Barcelona and the plane was so cramped and very uncomfortable and dirty. But we flew out of Madrid and that plane was much better. Would fly Iberia again.

8.0 ExcellentGlenn, Oct 2025MAD - BOS
Read more Iberia reviews

We flew into Barcelona and the plane was so cramped and very uncomfortable and dirty. But we flew out of Madrid and that plane was much better. Would fly Iberia again.

For what we are willing to pay for international air travel, our experience was very good. We had no problem checking in, we had very little wait time at the AA counter in Madrid, and the staff in Madrid were very helpful. The flight crew was helpful and courteous, the plane was on the newer side, and our assigned seats were together without us needing to purchase them. The flight took off on time and arrived early. Overall, it was a pleasant experience or as much as could be expected in economy for almost 10 hours.

Terrible customer service. I booked business class and the counter agent didn’t bother asking me about any choice or preferred seat, basically assigned me that last seat and couldn’t even answer if it was a business class seat. Also iberia lost my suitcase on my flight from JFK to MAD with the layover in BCN. Useless customer service at the counter. Thank goodness I happened to check the baggage claim area of the next flight in…there it was.

Boarding was easy, the flight left on time and even landed 20 minutes early. The food was plentiful and really good! The crew was kind & helpful. Overall it was an exceptional experience!

The flight was safe, confortable and convenient. Thank you. I hope to come back soon!

Delayed. Mismanagement of gate lines. Passengers arguing with eachother as a result of lack of organization by airline. Avoid this airline.

Because the plane was delayed from Madrid to LAX, we missed our connecting flight to Malaga. Iberia offered to book us a hotel room but I needed to be in Malaga that evening. I ended up buying train tickets to Malaga from Madrid. I also feel Iberia should compensate me for the cost of the train tickets because they didn't meet their travel obligation.

Terrible. Won’t fly again. Boarding was an issue. Took TWO hours to “find” my confirmed reservation. Crew at desk was super rude and unconcerned. Was not escorted through despite delay on their end. Almost missed fight and luggage arrived one day late…. Which I had to pick up by cab or wait even longer (not reimbursed).

Arrived on time. Great crew. Good food. Luggage delivered promptly

Left on time, arrived on time, despite weather, excellent service and food

Our flight was canceled and we were put on a different flight, but we were never notified of the change until we checked in. BOA provides no beverage service during the flight and there is no in-flight entertainment. Airline staff tried to tell us that we were not allowed one personal item and one carry-on bag per person, but instead that we were only allowed one item aboard per person, which contradicts their written luggage policy. Airline staff also claimed that a car seat counted against our carry-on allowance, even though our child had his own ticket and is required to use a car seat on board per airline policy.

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

BOA airplanes are so old and dirty, the bathroom was so nasty, it smelled so bad and had tape all over the cabinets. My chair wouldn't recline, we had no entertainment, the flight was super cold. The only positive thing about this flight is that I feel it's so old that they even serve food, like in the past! I travel a lot and nowadays the companies only serve some snacks or sometimes offer something to eat if you pay. Not the case with this flight. Never again flying with BOA. They are definetly the worst.

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Horrible experience. Flight cancelled. Arrived at destination 12 hs later. No one gave us an answer or any information. Very very poor service. We won’t ever travel again with Avianca

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

Not what it used to be. The sale of food makes them look greedy!

No food, terms when selling are not clear. To pricy for the service in general

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

why did we have to go through security mid flight

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

Seats are very tight even in Plus, no complimentary snacks or beverage

Everything you need to know for your flight from Madrid to Santa Cruz de la Sierra

Information on your arrival and departure airports

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