MAD - VVI

£312 Find Cheap Flights from Madrid to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 18/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Madrid to Santa Cruz de la Sierra (MAD-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Madrid to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Madrid to Santa Cruz de la Sierra

Mon, 1 Sep - Tue, 28 Oct
Avianca Logo
09:40 - 01:50MAD-VVI
22h 10m1 stop
Avianca Logo
03:40 - 13:25VVI-MAD
28h 45m1 stop
£585Avianca
Find Deal
Sun, 31 Aug - Mon, 15 Sep
Avianca Logo
09:40 - 01:50MAD-VVI
22h 10m1 stop
Avianca Logo
02:50 - 23:30VVI-MAD
14h 40m1 stop
£603Avianca
Find Deal
Mon, 1 Sep - Tue, 28 Oct
Avianca Logo
17:30 - 01:50MAD-VVI
38h 20m1 stop
Avianca Logo
03:05 - 22:35VVI-MAD
14h 30m1 stop
£616Avianca
Find Deal
Tue, 11 Nov - Wed, 26 Nov
Avianca Logo
10:50 - 02:35MAD-VVI
20h 45m1 stop
Avianca Logo
03:40 - 13:25VVI-MAD
28h 45m1 stop
£624Avianca
Find Deal
Sun, 31 Aug - Mon, 15 Sep
Avianca Logo
09:40 - 01:50MAD-VVI
22h 10m1 stop
Avianca Logo
02:50 - 11:10VVI-MAD
26h 20m1 stop
£628Avianca
Find Deal
Fri, 21 Nov - Fri, 5 Dec
Avianca Logo
00:35 - 02:00MAD-VVI
30h 25m1 stop
Avianca Logo
03:05 - 22:35VVI-MAD
14h 30m1 stop
£629Avianca
Find Deal
Sun, 9 Nov - Thu, 20 Nov
Avianca Logo
10:50 - 02:35MAD-VVI
20h 45m1 stop
Avianca Logo
03:40 - 23:20VVI-MAD
14h 40m1 stop
£654Avianca
Find Deal
Sat, 30 Aug - Mon, 15 Sep
Avianca Logo
01:30 - 01:50MAD-VVI
30h 20m1 stop
Avianca Logo
02:50 - 23:30VVI-MAD
14h 40m1 stop
£660Avianca
Find Deal
Wed, 22 Oct - Sat, 25 Oct
United Airlines Logo
11:15 - 22:17MAD-VVI
41h 02m2 stops
United Airlines Logo
01:09 - 08:05VVI-MAD
25h 56m2 stops
£809United Airlines
Find Deal
Tue, 11 Nov - Thu, 27 Nov
 Logo
19:35 - 11:05MAD-VVI
20h 30m2 stops
 Logo
13:10 - 15:40VVI-MAD
21h 30m2 stops
Expert advice

Expert advice for your flight from Madrid to Santa Cruz de la Sierra

 
Snippets provided in this section are AI-generated based on a summarisation of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers speedy Wi-Fi with packages for all needs during your flight.


Air Europa provides special meals including diabetic, gluten-free, and vegan options on transatlantic flights.

Iberia

Iberia’s Business class offers roomy seating with all-aisle access and comfortable bedding.


Enjoy Spanish cuisine with two meals and a variety of beverages on long-haul flights.

Read more about Iberiaby Marisa Garcia
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Read more
Booking Insights

KAYAK's insights & trends for Madrid to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Madrid to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Madrid to Santa Cruz de la Sierra?

What’s the cheapest day of the week to fly from Madrid to Santa Cruz de la Sierra?

The average price of all round-trip flights from Madrid to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Santa Cruz de la Sierra on a Friday and more expensive on a Thursday. On your return trip to Madrid, you should consider flying back on a Monday, and avoid Thursdays for better deals.

What is the cheapest month to fly from Madrid to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Santa Cruz de la Sierra is May, where tickets cost £589 (return) on average. On the other hand, the most expensive months are August and December, where the average cost of round-trip tickets is £1,074 and £1,055 respectively.

Can I save money by flying with a stopover from Madrid to Santa Cruz de la Sierra?

The average return price for all direct flights, flights with one stopover, and flights with two stopovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a stopover may cost you more time, but you can also save money on the route, with a 1 stop stopover the cheapest option at £1,237 on average.

How far in advance should I book a flight from Madrid to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Santa Cruz de la Sierra, you should book around 3 weeks before departure, which saves you about 27% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.


Good to know - Cheap tickets from Madrid to Santa Cruz de la Sierra

Low seasonOctober
Cheapest flight£312
Best time to beat the crowds (8% less expensive on average)
Most popular time to fly (35% more expensive on average)
Flight from Madrid to Santa Cruz de la Sierra

When to book flights from Madrid to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Madrid to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santa Cruz de la Sierra

  • What is the cheapest flight from Madrid to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Madrid to Santa Cruz de la Sierra was £416 for a one-way ticket and £779 for a return.

  • Which airports will I be using when flying from Madrid to Santa Cruz de la Sierra?

    Madrid and Santa Cruz de la Sierra are both served by 1 main airport. You will leave Madrid from Madrid Barajas and will be arriving at Santa Cruz de la Sierra Viru Viru Intl.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santa Cruz de la Sierra?

    Iberia, Lufthansa, Vueling, and Qatar Airways offer inflight Wi-Fi service on the Madrid to Santa Cruz de la Sierra flight route.

  • Which aircraft models fly most regularly from Madrid to Santa Cruz de la Sierra?

    The Boeing 787 Dreamliner is the aircraft model that flies most regularly on the Madrid to Santa Cruz de la Sierra flight route.

  • Which airline alliances offer flights from Madrid to Santa Cruz de la Sierra?

    oneworld, and SkyTeam are the airline alliances operating flights between Madrid and Santa Cruz de la Sierra, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Santa Cruz de la Sierra?

    You can catch a direct flight from Madrid to Santa Cruz de la Sierra on on Monday, Wednesday, Friday, and Sunday.

  • Which is the best airline for flights from Madrid to Santa Cruz de la Sierra, LATAM Airlines or BoA?

    The two airlines most popular with KAYAK users for flights from Madrid to Santa Cruz de la Sierra are LATAM Airlines and BoA. With an average price for the route of £886 and an overall rating of 7.5, LATAM Airlines is the most popular choice. BoA is also a great choice for the route, with an average price of £742 and an overall rating of 6.8.

  • How does KAYAK find such low prices on flights from Madrid to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Madrid with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Madrid to Santa Cruz de la Sierra?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl.
Find which airlines fly direct from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl

Monday

Air Europa

Air Europa

Wednesday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Friday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Saturday

Air Europa

Air Europa

Sunday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

See more direct flights

Direct returns

Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas

Monday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Tuesday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Thursday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Saturday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

See more direct flights

Reviews of the top 4 airlines flying from Madrid to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1822 reviews
8.1Crew
6.7Food
7.6Boarding
7.4Comfort
7.0Entertainment
Airline reviews

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

2.0 MediocreAnonymous, Jul 2025ATL - MIA
Read more LATAM Airlines reviews

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

entertainment was not good; the shoulder strap on Business class seat did not sit well across the body (more like across the neck); the food was not hot and the special meal promoted by insert in the menu was not available to us

The boarding and new bag drop-off process was confusing and causing massive delays.

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

It was a very good flight, no entertainment is the reason for not checking that box.

Our flight was cancelled and it took them 5 hours to reschedule and the next morning they said we still didn’t have a new ticket.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Horrible almost missed my flight because my 1st flight was delayed. Airline crew is so unprofessional. The people on the plane do whatever they want kids running screaming. Will never fly this airline again Suitcases never arrived

People point to America as the model of late stage capitalism. My friends, airlines in america at least give you WiFi, and they haven’t quite smashed people into cardboard tv dinner trays yet. Iberia has mastered the tv dinner seat and WiFi is 20 euros. Be serious yall.

Boarding was odd. Gates switched and had to take a bus to the plane. Luggage got lost. Still waiting on one bag. Flight itself was very nice!

Do Not Fly Iberia. Horrible experience. Iberia changes things at random -like the date of the flight and seat you have bought. After buying my flight, they contacted me and told me I had to return a day later. Then when I was boarding the flight, I discovered they had changed my window seat in a row away from the wing, to an aisle seat in front of the toilet! The worse seat on the plane. But it wasn’t just me- a family was scattered all over the plane. I was able to trade my seat because a father was separated from his son. Unfortunately the seat was the window seat directly over the wing, the loudest seat in the plane. I couldn’t sleep, even with noise cancelling earphones. Also, I ordered gluten free meal-which was tasteless and gave me cramps.

I have nothing but great things to say about the crew of the American Airlines flight from Madrid to Dallas. They were fantastic! I do, however, have some disregard for the flight attendant that was late in Dallas, causing us to further delay the boarding of our flight to Portland, and leading to the eventual cancellation of that flight. Because that crew-member was so late, we got caught-up in a weather-related ground stop, eventually causing our pilots to "time-out". So we couldn't get out of Dallas. We would have departed DFW on-time (and before the arrival of the thunderstorm) if not for the lateness of that crew member. The whole time the pilots couldn't tell us whether the flight would be cancelled, and that they couldn't get any information from the airline. By the time we knew the flight was cancelled, all of the flights for the following day were full. So, we didn't even get offered a viable option to get home. The American Airlines customer service desk at DFW was grossly under-staffed. And there were several people who waited in line for four-hours before being helped at that desk. We waited in line for almost 2-hours, until I was able to speak with a customer service agent on the phone (after being on-hold for over an hour). So, once we knew the information about how to get our bag in PDX, and that there weren't any options for flights the next day, we left the line & began searching for another way home. We eventually had to purchase a ticket home on a different airline, in order to get my wife to work on Monday. And we are pursuing a refund of that DFW-PDX leg of the journey. The good news is that the late flight attendant's hair was perfect. And she looked fantastic as she departed the airport & headed back home, while we all hunkered down to sleep in the terminal for the night.

They need to start flying on time. We lost 2 days of our time because they delayed flight both ways.

The flight delay in Dallas created a domino effect that impacted all of the connecting flights. It also increased the number of connections. I missed my flight from Casablanca to Marrakech because of the tight turnaround when landing in Casablanca. . CMN airport was understaffed. Only one person could help while other employees were just watching him. It was an extremely frustrating situation. People were crying and slamming their palms on the counter when speaking to the customer service provider, Allabough (man’s name?). Allabough couldn’t change my flight in the system. simultaneously, I was on the call with America. Airlines customer service rep named Solomon that said he couldn’t change it either. So, I took a ONYA voyages train to from Casablanca to Marrakech to get there on Friday June 26. This was unpredictable trip.

The flight was over two hours delayed. The aircraft was somewhat dated.

There's not enough leg room in economy class. The seats are very narrow as well.

Luggage arrived damaged and protective plastic was lost. I need customer service to contact me or the number for customer service. Thanks.

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

BOA airplanes are so old and dirty, the bathroom was so nasty, it smelled so bad and had tape all over the cabinets. My chair wouldn't recline, we had no entertainment, the flight was super cold. The only positive thing about this flight is that I feel it's so old that they even serve food, like in the past! I travel a lot and nowadays the companies only serve some snacks or sometimes offer something to eat if you pay. Not the case with this flight. Never again flying with BOA. They are definetly the worst.

This airline is always THE WORST. They seem to have flights moving to other times (late) 90% of the time. The airplanes are old, and the landing (i really don't know why) is 90% of the time shaky. I actually never buy tickets from BOA, I prefer other airlines by far.

Avianca is not what it used to be. So disappointing

why did we have to go through security mid flight

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

I receive a service for what I pay, so it is fair.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Excellent flight and one of the smoothest landing I’ve ever experienced

Everything you need to know for your flight from Madrid to Santa Cruz de la Sierra

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