PTY - CUZ

Find Cheap Flights from Panama City to Cusco – Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Direct flights
Not available
There are currently no direct flights between Panama City and Cusco. You'll need to take a connecting flight to reach the destination.
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When to book
22 weeks
in advance
Our data shows that travellers who book at least 22 weeks in advance save around 38% compared to booking last minute.
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Insights
When to travel
February
Cheapest • 15% price drop
October
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Bogotá El Dorado (BOG)
Cheapest • Avg £357 (return)
Lima J Chavez Intl (LIM)
Shortest trip • 7h 35m (one-way)
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We hope you enjoy your trip to Cusco!
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Flight Deals

Cheap Flights from Panama City to Cusco (PTY-CUZ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Panama City to Cusco

Multiple Airlines Logo
PTY  Tocumen Airport, Panama-CUZ Cusco Velazco Astete
1642 mimulti-stop
Multiple Airlines Logo
CUZ  Cusco Velazco Astete-PTY Tocumen Airport, Panama
1642 mimulti-stop
Multiple Airlines
Booking Insights

Price, demand, and travel trends for Panama City to Cusco flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights from Panama City to Cusco with more confidence.

What's the cheapest day of the week to fly from Panama City to Cusco?

Tuesday is the cheapest day of the week to fly from Panama City to Cusco and is 15% cheaper than the average day. Friday is the most expensive day with flight prices 24% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Panama City to Cusco?

•February is the cheapest month to fly from Panama City to Cusco at £298 return.
•August (£482) and July (£436) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 61% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Panama City to Cusco the cheapest?

Flights from Panama City to Cusco are cheapest 22 weeks before departure. Booking in this window typically costs about 38% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Panama City to Cusco flights

Low season

January
Best time to beat the crowds (13% less expensive on average)
Most popular time to fly (19% more expensive on average)

When to book flights from Panama City to Cusco

Are your dates flexible? Find out the best times to travel from Panama City to Cusco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Panama City to Cusco flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines, and booking questions.

  • Which airports can I use when flying from Panama City to Cusco?

    Flights from Panama City to Cusco usually depart from Panama City Tocumen Intl (PTY) and arrive at Cusco Velazco Astete (CUZ).

  • Which airports do connecting flights from Panama City to Cusco pass through?

    Connecting flights from Panama City to Cusco most commonly pass through:

    • Bogotá El Dorado (BOG) – 85% of one-stop connections
    • Lima J Chavez Intl (LIM) – 15% of one-stop connections
    Together, these airports account for 100% of one-stop bookings on this route.

  • Can I save money by using flexible dates for flights from Panama City to Cusco?

    Yes. Being flexible with your travel dates can save you up to 32% on the Panama City to Cusco route. Tuesday is the cheapest departure day at £298 return on average, while Friday is the most expensive at £436, a difference of £138. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Cusco?

    Some of the most popular sights in Cusco are Plaza de Armas and Cusco San Pedro Market. These are among the most viewed places in Cusco on KAYAK.

  • How expensive are last-minute Panama City to Cusco flights?

    Last-minute fares on this route (booked within 2 weeks of departure) run 38% above the route average of £350. Book 22 weeks before departure for the lowest fares.

  • How long is a flight from Panama City to Cusco?

    A direct flight from Panama City to Cusco takes 0h 00m, covering 1,642 miles.

  • Do I need a passport to fly from Panama City to Cusco?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much time can I save by choosing a different stopover airport from Panama City to Cusco?

    Flying via Lima J Chavez Intl (LIM) gives the shortest average 1-stop total travel time of 7h 35m, compared to 8h 59m via Bogotá El Dorado (BOG).

  • Which car hire options are available at Cusco Velazco Astete Airport (CUZ)?

    Cusco Velazco Astete Airport (CUZ) hosts 5 major car hire companies, with daily rates starting from around £2 for economy cars. Top options include:
    • Sixt
    • Hertz
    • Thrifty
    • Europcar
    • Dollar

  • How much should I expect to pay for a Panama City to Cusco flight?

    Return flights from Panama City to Cusco range from £298 to £441, with an average of £350 over the past 12 months. Anything below £298 counts as a good deal.

Your guide to booking Panama City to Cusco flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure instead of Friday. On this route, Tuesday flights average £298 – about £138 less than Friday (32% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 22 weeks before you fly. On this route, that window historically saves about 38% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Panama City to Cusco trip for February. Fares historically average £298 return in that month – typically £184 less than the most expensive month, which is August (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Cusco Velazco Astete Airport.
    - Hostal Samichay
    - Hotel Agustos Cusco

More options for your flight from Panama City to Cusco

Complete your trip to Cusco with a hotel stay or car hire

Car hire in Cusco
Hotels in Cusco