£298 Find Cheap Flights from Panama City to San Francisco – Compare and Save

These are the earliest and latest flight times available from Panama City to San Francisco:

• Earliest: departs at 12:38 and lands at 20:19
• Latest: departs at 18:47 and lands at 02:28.

The flight takes about 7h 41m.

A direct flight from Panama City to San Francisco takes 7h 41m, covering 3,318 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Return flights from Panama City to San Francisco range from £523 to £650, with an average of £580 over the past 12 months. Anything below £523 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 19% above the £580 route average. Book 22 weeks before departure for the lowest fares.

On this route, stopover flights are cheaper than direct options on average. Stopover fares average £511 return via San Salvador El Salvador Intl (SAL), compared with £591 for direct.

The Boeing 737 MAX 9 family is used most often on this route, operated mainly by Copa Airlines and United Airlines. Other aircraft seen on the route include Boeing 737 MAX 8 variants.

Afternoon is the busiest departure period on Panama City to San Francisco flights, with 50% leaving in that window. Evening departures account for 50%, Morning flights for 0%, and Night flights for 0%.

Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about £535 to £4,125. That means the highest observed fare was about 8x higher than the lowest one.

One-way fares from Panama City to San Francisco are currently higher than usual. Average one-way flight prices are about £690, which is 88% above the typical average for this route.

San Francisco Airport (SFO) hosts 5 major car hire companies, with daily rates starting from around £12 for economy cars. Top options include:

• Europcar
• Thrifty
• Dollar
• Hertz
• Fox

Flights from Panama City to San Francisco usually depart from Panama City Tocumen Intl (PTY) and arrive at San Francisco (SFO).

One-stop flights from Panama City to San Francisco most commonly connect through:

• San Salvador El Salvador Intl (SAL) – 66% of one-stop connections
• Houston George Bush Intcntl (IAH) – 28% of one-stop connections
• Miami (MIA) – 2% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) – 2% of one-stop connections

Yes. Flexible dates can save you up to 7% on flights from Panama City to San Francisco. Thursday is the cheapest departure day at £570 return on average, while Sunday is the most expensive at £611, a difference of £41.

KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

Only Copa Airlines operates flights between Panama City and San Francisco.

Flying via San Salvador El Salvador Intl (SAL) gives the shortest average 1-stop total travel time of 9h 41m, compared to 10h 06m via San José del Cabo Los Cabos (SJD) and 10h 37m via Houston George Bush Intcntl (IAH).

San Francisco is 2 hours behind Panama City (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Some of the most popular sights in San Francisco are Union Square, Fisherman's Wharf, and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

Among airlines operating Panama City to San Francisco flights:

• Copa Airlines: offers extra legroom; offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a cabin bag and a checked bag in Economy class

Baggage allowance can vary by ticket type, cabin class, route, and airline, so always check the fare details before booking.