GUA - SCL

£380 Find Cheap Flights from Guatemala City to Santiago – Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest return flight
£464
Typical prices: £421-£519
Copa Airlines
Mon 5/11Sat 10/11
GUA - SCL • 2 stops
Cheapest one-way flight
£380
Typical prices: £216-£290
Arajet
Sun 18/2
GUA - SCL • 1 stop
Direct flights
Not available
There are currently no direct flights between Guatemala City and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
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When to book
7 weeks
in advance
Our data shows that travellers who book at least 7 weeks in advance save around 13% compared to booking last minute.
Insights
Insights
When to travel
April
Cheapest • 10% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Medellín Jose Maria Cordova Intl (MDE)
Cheapest • Avg £435 (return)
Panama City Tocumen Intl (PTY)
Shortest trip • 11h (one-way)
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Insights
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We hope you enjoy your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guatemala City to Santiago (GUA-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Guatemala City to Santiago

Thu, 5 Nov - Tue, 10 Nov
Copa Airlines Logo
06:19 - 23:36GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
14h 17m2 stops San José Juan Santamaria Intl Panama City Tocumen Intl
Copa Airlines Logo
05:07 - 23:06SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
20h 59m1 stop Panama City Tocumen Intl
£464Copa Airlines
Mon, 8 Feb - Sat, 27 Feb
Copa Airlines Logo
02:25 - 20:19GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
14h 54m1 stop Panama City Tocumen Intl
Copa Airlines Logo
01:17 - 08:48SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
10h 31m1 stop Panama City Tocumen Intl
£476Copa Airlines
Thu, 3 Dec - Wed, 9 Dec
Copa Airlines Logo
06:24 - 02:48GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
17h 24m2 stops San José Juan Santamaria Intl Panama City Tocumen Intl
Copa Airlines Logo
03:48 - 11:51SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
11h 03m1 stop Panama City Tocumen Intl
£483Copa Airlines
Thu, 19 Nov - Thu, 26 Nov
Copa Airlines Logo
06:19 - 03:38GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
18h 19m2 stops San José Juan Santamaria Intl Panama City Tocumen Intl
Copa Airlines Logo
12:15 - 22:42SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
13h 27m1 stop Panama City Tocumen Intl
£496Copa Airlines
Wed, 2 Dec - Tue, 8 Dec
Copa Airlines Logo
02:22 - 20:11GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
14h 49m1 stop Panama City Tocumen Intl
Copa Airlines Logo
01:07 - 09:40SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
11h 33m1 stop Panama City Tocumen Intl
£503Copa Airlines
Sun, 6 Dec - Sun, 13 Dec
Copa Airlines Logo
06:24 - 23:35GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
14h 11m2 stops San José Juan Santamaria Intl Panama City Tocumen Intl
Copa Airlines Logo
12:20 - 08:45SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
23h 25m1 stop Panama City Tocumen Intl
£507Copa Airlines
Mon, 1 Feb - Thu, 18 Feb
Copa Airlines Logo
10:43 - 00:29GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
10h 46m1 stop Panama City Tocumen Intl
Copa Airlines Logo
05:18 - 22:45SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
20h 27m1 stop Panama City Tocumen Intl
£509Copa Airlines
Wed, 2 Dec - Sun, 13 Dec
Copa Airlines Logo
10:42 - 00:23GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
10h 41m1 stop Panama City Tocumen Intl
Copa Airlines Logo
03:48 - 11:51SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
11h 03m1 stop Panama City Tocumen Intl
£516Copa Airlines
Thu, 26 Nov - Wed, 2 Dec
Copa Airlines Logo
06:19 - 00:24GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
15h 05m2 stops San José Juan Santamaria Intl Panama City Tocumen Intl
Copa Airlines Logo
12:20 - 08:45SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
23h 25m1 stop Panama City Tocumen Intl
£527Copa Airlines
Sun, 31 Jan - Wed, 17 Feb
Copa Airlines Logo
04:18 - 23:41GUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
16h 23m1 stop Panama City Tocumen Intl
Copa Airlines Logo
03:58 - 21:36SCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
20h 38m2 stops Panama City Tocumen Intl San José Juan Santamaria Intl
£529Copa Airlines
Booking Insights

Price, demand, and travel trends for Guatemala City to Santiago flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights with more confidence.

How much is a return flight from Guatemala City to Santiago?

Return flights from Guatemala City to Santiago typically range from £421 to £519. The lowest price found in the past 5 days was £464 on Copa Airlines.

What's the cheapest day of the week to fly from Guatemala City to Santiago?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Guatemala City to Santiago. It’s 3% cheaper than the average day, while Wednesday is the most expensive, with prices 6% higher.

What is the cheapest month to fly from Guatemala City to Santiago?

•April is the cheapest month to fly from Guatemala City to Santiago at £417 return.
•October (£503) and December (£503) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 20% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Guatemala City to Santiago the cheapest?

Flights from Guatemala City to Santiago are cheapest 7 weeks before departure. Booking in this window typically costs about 13% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Guatemala City to Santiago flights

Low season

June

Cheapest flight

£380
Beat the crowds with an average 47% drop in traveller numbers.
The most popular month to fly with an average 95% increase in traveller numbers.
One-way flight from Guatemala City to Santiago

When to book flights from Guatemala City to Santiago

Are your dates flexible? Find out the best times to travel from Guatemala City to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Guatemala City to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines, and booking tips.

  • Which cabin classes can I book on flights from Guatemala City to Santiago?

    Only Economy class is available on flights from Guatemala City to Santiago.

  • How long is a flight from Guatemala City to Santiago?

    A direct flight from Guatemala City to Santiago takes 00m, covering 3,559 miles.

  • Do I need a passport to fly from Guatemala City to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Guatemala City to Santiago flight?

    Return flights from Guatemala City to Santiago range from £421 to £519, with an average of £463 over the past 12 months. Anything below £421 counts as a good deal.

  • How expensive are last-minute Guatemala City to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 6% above the £463 route average. Book 7 weeks before departure for the lowest fares.

  • Have flight prices from Guatemala City to Santiago changed much recently?

    Yes. Based on fares seen in the past 5 days, return prices on this route varied from about £464 to £864. That means the highest observed fare was about 86% higher than the lowest one.

  • How are flight prices from Guatemala City to Santiago looking right now?

    One-way fares from Guatemala City to Santiago are currently higher than usual. Average one-way flight prices are about £404, which is 56% above the typical average for this route.

  • Which car hire options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car hire companies, with daily rates starting from around £4 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Guatemala City to Santiago?

    Flights from Guatemala City to Santiago usually depart from Guatemala City La Aurora (GUA) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airports do connecting flights from Guatemala City to Santiago pass through?

    One-stop flights from Guatemala City to Santiago most commonly connect through:

    • Panama City Tocumen Intl (PTY) – 52% of one-stop connections
    • Bogotá El Dorado (BOG) – 47% of one-stop connections
    • Medellín Jose Maria Cordova Intl (MDE) – 0% of one-stop connections

  • Can I save money by using flexible dates for flights from Guatemala City to Santiago?

    Yes. Flexible dates can save you up to 9% on flights from Guatemala City to Santiago. Tuesday is the cheapest departure day at £450 return on average, while Wednesday is the most expensive at £494, a difference of £44.

    KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different stopover airport from Guatemala City to Santiago?

    Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time of 11h, compared to 12h 45m via Bogotá El Dorado (BOG) and 22h 48m via Medellín Jose Maria Cordova Intl (MDE).

  • What is the time difference between Guatemala City and Santiago?

    Santiago is 3 hours ahead of Guatemala City (Chile Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Museum of Contemporary Art is one of the most viewed places in Santiago on KAYAK.

Your guide to booking Guatemala City to Santiago flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Wednesday. On this route, Tuesday flights average £450, about £44 less than Wednesday fares (9% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 7 weeks before you fly. On this route, that window historically saves about 13% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Guatemala City to Santiago trip for April. Fares historically average £417 return in that month – typically £87 less than the most expensive month, which is October (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

More options for your flight from Guatemala City to Santiago

Complete your trip to Santiago with a hotel stay or car hire

Car hire in Santiago
Hotels in Santiago
Holidays in Santiago