LIS - PTY

£447 Find Cheap Flights from Lisbon to Panama City – Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest return flight
£506
Typical prices: £523-£722
Air Europa
Tue 27/2Tue 6/3
LIS - PTY • 1 stop
Cheapest one-way flight
£447
Typical prices: £339-£539
Air Europa
Fri 26/10
LIS - PTY • 1 stop
Direct flights
Not available
There are currently no direct flights between Lisbon and Panama City. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
7 weeks
in advance
Our data shows that travellers who book at least 7 weeks in advance save around 31% compared to booking last minute.
Insights
Insights
When to travel
June
Cheapest • 11% price drop
April
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Madrid Barajas (MAD)
Cheapest • Avg £644 (return)
Miami (MIA)
Shortest trip • 14h 23m (one-way)
Insights
Insights
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We hope you enjoy your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Lisbon to Panama City (LIS-PTY)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Lisbon to Panama City

Sat, 27 Feb - Sat, 6 Mar
Air Europa Logo
11:35 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
13h 10m1 stop Madrid Barajas
Air Europa Logo
21:30 - 15:15PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
12h 45m1 stop Madrid Barajas
£506Air Europa
Fri, 12 Feb - Fri, 26 Feb
Air Europa Logo
08:00 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
16h 45m1 stop Madrid Barajas
Air Europa Logo
21:30 - 06:50PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
28h 20m1 stop Madrid Barajas
£511Air Europa
Wed, 3 Feb - Mon, 22 Feb
Air Europa Logo
11:35 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
13h 10m1 stop Madrid Barajas
Air Europa Logo
21:30 - 15:15PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
12h 45m1 stop Madrid Barajas
£525Air Europa
Mon, 1 Feb - Mon, 15 Mar
Air Europa Logo
07:40 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
17h 05m1 stop Madrid Barajas
Air Europa Logo
21:30 - 15:15PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
12h 45m1 stop Madrid Barajas
£531Air Europa
Mon, 1 Feb - Mon, 15 Mar
Air Europa Logo
11:35 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
13h 10m1 stop Madrid Barajas
Air Europa Logo
21:30 - 19:15PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
16h 45m1 stop Madrid Barajas
£531Air Europa
Tue, 3 Nov - Tue, 24 Nov
KLM Logo
05:00 - 05:48LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
29h 48m3 stops Amsterdam Schiphol Simpson Bay Princess Juliana Port of Spain Piarco Intl
KLM Logo
18:45 - 18:50PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
19h 05m1 stop Amsterdam Schiphol
£542KLM
Tue, 2 Feb - Mon, 22 Feb
Air Europa Logo
07:40 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
17h 05m1 stop Madrid Barajas
Air Europa Logo
21:30 - 15:15PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
12h 45m1 stop Madrid Barajas
£551Air Europa
Mon, 2 Nov - Tue, 24 Nov
Air Europa Logo
11:35 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
13h 10m1 stop Madrid Barajas
Air Europa Logo
21:30 - 19:15PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
16h 45m1 stop Madrid Barajas
£556Air Europa
Tue, 2 Feb - Sat, 20 Feb
Air Europa Logo
07:40 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
17h 05m1 stop Madrid Barajas
Air Europa Logo
21:30 - 15:15PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
12h 45m1 stop Madrid Barajas
£577Air Europa
Sun, 1 Nov - Thu, 19 Nov
Air Europa Logo
08:00 - 19:45LIS  Lisbon Humberto Delgado-PTY Panama City Tocumen Intl
16h 45m1 stop Madrid Barajas
Air Europa Logo
21:30 - 15:15PTY  Panama City Tocumen Intl-LIS Lisbon Humberto Delgado
12h 45m1 stop Madrid Barajas
£578Air Europa
Booking Insights

Price, demand, and travel trends for Lisbon to Panama City flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights from Lisbon to Panama City with more confidence.

How much is a return flight from Lisbon to Panama City?

Return flights from Lisbon to Panama City start at £506. Prices are below average for this route right now, with typical return fares ranging from £523 to £722. The lowest price found in the past 5 days was £506 on Air Europa.

What's the cheapest day of the week to fly from Lisbon to Panama City?

Wednesday is the cheapest day of the week to fly from Lisbon to Panama City and is 10% cheaper than the average day. Friday is the most expensive day with flight prices 12% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Lisbon to Panama City?

  • June is the cheapest month to fly from Lisbon to Panama City at £527 return.
  • August (£867) and December (£787) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 64% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Lisbon to Panama City the cheapest?

Flights from Lisbon to Panama City are cheapest 7 weeks before departure. Booking in this window typically costs about 31% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Lisbon to Panama City flights

Low season

September

Cheapest flight

£447
Best time to beat the crowds (4% less expensive on average)
Most popular time to fly (6% more expensive on average)
Flights from Lisbon to Panama City

When to book flights from Lisbon to Panama City

Are your dates flexible? Find out the best times to travel from Lisbon to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Lisbon to Panama City flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines, and booking questions.

  • Which airports can I use when flying from Lisbon to Panama City?

    Flights from Lisbon to Panama City usually depart from Lisbon Humberto Delgado (LIS) and arrive at Panama City Tocumen Intl (PTY).

  • Which cabin classes can I book on flights from Lisbon to Panama City?

    Only Economy class is available on flights from Lisbon to Panama City.

  • Which airports do connecting flights from Lisbon to Panama City pass through?

    One-stop flights from Lisbon to Panama City most commonly connect through:

    • Madrid Barajas (MAD) – 91% of one-stop connections
    • Istanbul (IST) – 3% of one-stop connections
    • Amsterdam Schiphol (AMS) – 2% of one-stop connections
    • Paris Charles de Gaulle (CDG) – 2% of one-stop connections

    Madrid Barajas (MAD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Lisbon to Panama City?

    Yes. Being flexible with your travel dates can save you up to 20% on the Lisbon to Panama City route. Wednesday is the cheapest departure day at £537 return on average, while Friday is the most expensive at £670, a difference of £133. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Panama City?

    Multicentro Panama is one of the most viewed places in Panama City on KAYAK.

  • How expensive are last-minute Lisbon to Panama City flights?

    Last-minute fares on this route (booked within 2 weeks of departure) run 18% above the route average of £593. Book 7 weeks before departure for the lowest fares.

  • How long is a flight from Lisbon to Panama City?

    A direct flight from Lisbon to Panama City takes 0h 00m, covering 4,762 miles.

  • Do I need a passport to fly from Lisbon to Panama City?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Lisbon to Panama City changed much recently?

    Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about £506 to £1,550. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Lisbon to Panama City looking right now?

    One-way fares from Lisbon to Panama City are currently higher than usual. Average one-way flight prices are about £1,038, which is 140% above the typical average for this route.

  • How much time can I save by choosing a different stopover airport from Lisbon to Panama City?

    Flying via Madrid Barajas (MAD) gives the shortest average 1-stop total travel time of 14h 22m, compared to 14h 23m via Miami (MIA) and 15h 50m via Newark (EWR).

  • What is the time difference between Lisbon and Panama City?

    Panama City is 6 hours behind Lisbon (Eastern Time vs Western European Time). Plan for the time shift when scheduling connections or first-day activities.

  • Which car hire options are available at Panama City Tocumen Intl Airport (PTY)?

    Panama City Tocumen Intl Airport (PTY) hosts 5 major car hire companies, with daily rates starting from around £1 for economy cars. Top options include:
    · Avis
    · Europcar
    · Ace
    · Budget
    · Hertz

  • How much should I expect to pay for a Lisbon to Panama City flight?

    Return flights from Lisbon to Panama City range from £523 to £722, with an average of £593 over the past 12 months. Anything below £523 counts as a good deal.

Your guide to booking Lisbon to Panama City flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure instead of Friday. On this route, Wednesday flights average £537 – about £133 less than Friday (20% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 7 weeks before you fly. On this route, that window historically saves about 31% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Lisbon to Panama City trip for June. Fares historically average £527 return in that month – typically £340 less than the most expensive month, which is August (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City Tocumen Intl Airport.
    - Riande Aeropuerto Hotel & Casino

More options for your flight from Lisbon to Panama City

Complete your trip to Panama City with a hotel stay or car hire

Car hire in Panama City
Hotels in Panama City
Holidays in Panama City