MAD - SCL

£346 Find Cheap Flights from Madrid to Santiago – Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santiago departing on 26/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest return fare
£597
Typical prices: £723-£964
Avianca
Sun 13/9Tue 29/9
MAD - SCL • 1 stop
Cheapest direct flights
£638
Typical prices: £708-£934
LATAM Airlines
Mon 9/11Mon 16/11
MAD - SCL • Direct
Top airlines
Cheapest • from £597 (return)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Direct flights
You can fly direct with Iberia and LATAM Airlines. Average duration is 13h 24m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 84% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
Top stopover airports
Cheapest • Avg £661 (return)
Shortest trip • 18h 00m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travellers who book at least 7 weeks in advance save around 22% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 18% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Santiago!
Flight Deals
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Expert advice
Flight Deals

Cheap Flights from Madrid to Santiago (MAD-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Madrid to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Madrid to Santiago

Sun, 13 Sep - Tue, 29 Sep
Avianca Logo
08:10 - 00:20
MAD
-
SCL
21h 10m
1 stop
Avianca Logo
07:40 - 00:20
SCL
-
MAD
35h 40m
1 stop
£597Avianca
Wed, 2 Dec - Thu, 4 Feb
Delta Logo
11:55 - 07:40
MAD
-
SCL
23h 45m
1 stop
Delta Logo
21:50 - 10:55
SCL
-
MAD
33h 05m
1 stop
£602Delta
Thu, 5 Nov - Fri, 20 Nov
Delta Logo
10:00 - 07:40
MAD
-
SCL
49h 40m
2 stops
Delta Logo
23:10 - 08:00
SCL
-
MAD
52h 50m
2 stops
£603Delta
Thu, 5 Nov - Thu, 12 Nov
Delta Logo
11:55 - 07:40
MAD
-
SCL
23h 45m
1 stop
Delta Logo
23:10 - 08:00
SCL
-
MAD
28h 50m
2 stops
£604Delta
Tue, 8 Dec - Thu, 11 Feb
Delta Logo
11:55 - 07:40
MAD
-
SCL
23h 45m
1 stop
Delta Logo
23:10 - 08:00
SCL
-
MAD
28h 50m
2 stops
£605Delta
Wed, 21 Oct - Wed, 4 Nov
Delta Logo
09:50 - 08:15
MAD
-
SCL
27h 25m
1 stop
Delta Logo
23:10 - 13:20
SCL
-
MAD
34h 10m
2 stops
£615Delta
Sun, 6 Sep - Wed, 16 Sep
Delta Logo
14:35 - 08:15
MAD
-
SCL
46h 40m
2 stops
Delta Logo
20:40 - 15:35
SCL
-
MAD
37h 55m
2 stops
£617Delta
Mon, 23 Nov - Tue, 8 Dec
Delta Logo
11:55 - 07:40
MAD
-
SCL
23h 45m
1 stop
Delta Logo
23:10 - 11:30
SCL
-
MAD
32h 20m
2 stops
£618Delta
Thu, 20 Aug - Sun, 30 Aug
Delta Logo
09:50 - 07:15
MAD
-
SCL
27h 25m
1 stop
Delta Logo
20:40 - 11:20
SCL
-
MAD
32h 40m
2 stops
£618Delta
Thu, 20 Aug - Tue, 8 Dec
Delta Logo
09:50 - 07:15
MAD
-
SCL
27h 25m
1 stop
Delta Logo
23:10 - 15:20
SCL
-
MAD
36h 10m
2 stops
£619Delta
Booking Insights

KAYAK’s insights & trends for Madrid to Santiago flights

Get data-powered insights and trends into flights from Madrid to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a return flight from Madrid to Santiago?

This analysis is based on the cheapest return trip price found on KAYAK in the last 12 months by searching for a flight from Madrid to Santiago departing in September.

What’s the cheapest day of the week to fly from Madrid to Santiago?

The average price of all round-trip flights from Madrid to Santiago clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Madrid to Santiago, look for departures on Fridays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Santiago, Sunday is the cheapest day to fly and Thursday is the most expensive.

What is the cheapest month to fly from Madrid to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Santiago is May, where tickets cost £681 (return) on average. On the other hand, the most expensive months are July and December, where the average cost of round-trip tickets is £1,090 and £1,006 respectively.

Can I save money by flying with a stopover from Madrid to Santiago?

The average return price for all direct flights, flights with one stopover, and flights with two stopovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a stopover may cost you more time, but you can also save money on the route, with a 2 stops stopover the cheapest option at £611 on average.

How far in advance should I book a flight from Madrid to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Santiago, you should book around 7 weeks before departure, which saves you about 22% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 16 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Santiago

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on Iberia and LATAM Airlines

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Good to know - Cheap tickets from Madrid to Santiago

Low season

June

Cheapest flight

£346
Best time to beat the crowds (5% less expensive on average)
Most popular time to fly (21% more expensive on average)
Flight from Madrid to Santiago

When to book flights from Madrid to Santiago

Are your dates flexible? Find out the best times to travel from Madrid to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santiago

  • What is the cheapest flight from Madrid to Santiago?

    In the last 5 days, the lowest price for a flight from Madrid to Santiago was £346 for a one-way ticket and £597 for a return.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santiago?

    Iberia, Qatar Airways, LATAM Airlines, and Vueling offer inflight Wi-Fi service on the Madrid to Santiago flight route.

  • Which aircraft models fly most regularly from Madrid to Santiago?

    The Airbus A350-900 is the aircraft model that flies most regularly on the Madrid to Santiago flight route.

  • Which airline alliances offer flights from Madrid to Santiago?

    oneworld is the only airline alliance operating flights between Madrid and Santiago.

  • On which days can I fly direct from Madrid to Santiago?

    There are direct flights from Madrid to Santiago on a daily basis.

  • Which is the best airline for flights from Madrid to Santiago, LATAM Airlines or Iberia?

    The two airlines most popular with KAYAK users for flights from Madrid to Santiago are LATAM Airlines and Iberia. With an average price for the route of £929 and an overall rating of 7.4, LATAM Airlines is the most popular choice. Iberia is also a great choice for the route, with an average price of £927 and an overall rating of 7.0.

  • How does KAYAK find such low prices on flights from Madrid to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Santiago with an airline and back to Madrid with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Santiago

  • Looking for a cheap flight from Santiago to Madrid? 25% of our users found flights on this route for £645 or less round-trip.

Prefer to fly direct from Madrid to Santiago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Santiago Arturo Merino Benitez.
Find which airlines fly direct from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santiago Arturo Merino Benitez

Monday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Tuesday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Wednesday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Thursday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Friday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Saturday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Sunday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Madrid Barajas

Monday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Tuesday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Wednesday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Thursday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Friday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Saturday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Sunday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

See more direct flights

Reviews of the top airlines flying from Madrid to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1962 reviews
7.3Comfort
7.0Entertainment
8.0Crew
6.7Food
7.5Boarding
Airline reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

10.0 ExcellentSarah, Jan 2026
ANF - SCL
Read more LATAM Airlines reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

It was a short flight, sits uncomfortable No food was provided. Staff was lovely and kind .

The crew was amazing. The best in the last times. Great group of people.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

All four segments of my trip on Iberia were late for various reasons. No apparent effort to stay on schedule. Never flying Iberia again.

The flight from Madrid to Boston was awful. Without prior warning, I was seated in the row in front of an exit row where my seat did not recline. The person in front of me reclined, reducing my already tiny space further. This was the WORST flight I've ever had.

Overall it was okay. Just the lost baggage and how they are handling it

Puddle-hopper. Quick-ish flight. Don’t expect to have much/any in-flight entertainment (movies/TV, etc).

Worst flight I ever experienced, what was supposed to a 7 hour flight ended being 13 hours on a plane with no ac and the worst cabin I have ever seen. Never again.

Horrible seat at the back. Crew was very kind. Packed plane. Wordy pilot bragging about Iberia being punctual when many of us came from Alicante flight that was delayed an hour and many lost connection and we lost our luggage. Still waiting for it

Excellent plane, 787. Very good seat and additional stuff they provide. Good food. Very good staff.

Excellent except WiFi is a Must on Biz class 10 hour flight ! Didn’t work entire flight. SW doesn’t do that.

Excellent crew, food and service. Boarding via bus is always a pain but overall really good

Stewardess was not attentive at all asked for a bottle of water never came by 15 minutes later I asked her she said that she forgot there was only 12 people in first class and two stewardess unacceptable I ordered the fish was the last person to order. They said that they did not have any had to have a different item pasta at the inside of it because I was diabetic. Worst experience I ever had will never travel this airline again.

Everything you need to know for your flight from Madrid to Santiago

Information on your arrival and departure airports