MAD - SCL

£371 Find Cheap Flights from Madrid to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santiago departing on 17/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santiago, as well as popular online travel agencies
Travellers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest return fare
£641
Typical prices: £883-£673
Delta
Mon 28/9Sat 23/1
MAD - SCL • 2 stops
Cheapest direct flights
£676
Typical prices: £931-£698
Iberia
Thu 7/5Tue 9/6
MAD - SCL • Direct
Advice from real travellers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Iberia’s Premium Economy has a 37” seat pitch.
LATAM’s 787 Dreamliners use 3-3-3 economy seating.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Cheapest • from £641 (return)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
+1
Direct flights
You can fly direct with Iberia and LATAM Airlines. Average duration is 13h 21m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 88% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
Top stopover airports
Cheapest • Avg £657 (return)
Shortest trip • 18h 00m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travellers who book at least 13 weeks in advance save around 16% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 16% price drop
Most popular
Good to know
Good to know
+1
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Good to know
Good to know
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Start a new search
KAYAK searches hundreds of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Madrid to Santiago (MAD-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Madrid to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Madrid to Santiago

Mon, 28 Sep - Sat, 23 Jan
Delta Logo
14:35 - 08:15
MAD
-
SCL
46h 40m
2 stops
Delta Logo
21:50 - 13:40
SCL
-
MAD
35h 50m
2 stops
£641Delta
Sun, 17 May - Mon, 25 May
Delta Logo
09:50 - 07:15
MAD
-
SCL
27h 25m
1 stop
Delta Logo
20:40 - 16:25
SCL
-
MAD
37h 45m
2 stops
£642Delta
Wed, 16 Sep - Sun, 4 Oct
Delta Logo
09:50 - 08:15
MAD
-
SCL
27h 25m
1 stop
Delta Logo
20:40 - 12:15
SCL
-
MAD
34h 35m
1 stop
£646Delta
Thu, 7 May - Sat, 23 May
Delta Logo
12:45 - 07:15
MAD
-
SCL
24h 30m
2 stops
Delta Logo
20:40 - 06:20
SCL
-
MAD
51h 40m
2 stops
£654Delta
Mon, 12 Oct - Sun, 6 Dec
Delta Logo
14:35 - 08:15
MAD
-
SCL
46h 40m
2 stops
Delta Logo
23:10 - 09:55
SCL
-
MAD
30h 45m
1 stop
£655Delta
Sun, 23 Aug - Sun, 6 Dec
Delta Logo
09:50 - 07:15
MAD
-
SCL
27h 25m
1 stop
Delta Logo
23:10 - 09:55
SCL
-
MAD
30h 45m
1 stop
£656Delta
Wed, 3 Jun - Wed, 10 Jun
LATAM Airlines Logo
23:55 - 07:15
MAD
-
SCL
13h 20mdirect
LATAM Airlines Logo
16:00 - 14:05
SCL
-
MAD
16h 05m
1 stop
£658LATAM Airlines
Mon, 24 Aug - Wed, 27 Jan
Delta Logo
06:00 - 07:15
MAD
-
SCL
31h 15m
2 stops
Delta Logo
21:50 - 10:15
SCL
-
MAD
32h 25m
2 stops
£658Delta
Tue, 19 May - Mon, 25 May
Delta Logo
06:00 - 07:15
MAD
-
SCL
31h 15m
2 stops
Delta Logo
20:40 - 16:25
SCL
-
MAD
37h 45m
2 stops
£660Delta
Wed, 20 May - Sun, 24 May
Delta Logo
14:35 - 07:15
MAD
-
SCL
46h 40m
2 stops
Delta Logo
20:40 - 06:20
SCL
-
MAD
51h 40m
2 stops
£662Delta
Booking Insights

KAYAK’s insights & trends for Madrid to Santiago flights

Get data-powered insights and trends into flights from Madrid to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a return flight from Madrid to Santiago?

This analysis is based on the cheapest return trip price found on KAYAK in the last 12 months by searching for a flight from Madrid to Santiago departing in September.

What’s the cheapest day of the week to fly from Madrid to Santiago?

The average price of all round-trip flights from Madrid to Santiago clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Madrid to Santiago, look for departures on Mondays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from Santiago, Wednesday is the cheapest day to fly and Saturday is the most expensive.

What is the cheapest month to fly from Madrid to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Santiago is March, where tickets cost £701 (return) on average. On the other hand, the most expensive months are July and December, where the average cost of round-trip tickets is £1,048 and £988 respectively.

Can I save money by flying with a stopover from Madrid to Santiago?

The average return price for all direct flights, flights with one stopover, and flights with two stopovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a stopover may cost you more time, but you can also save money on the route, with a 2 stops stopover the cheapest option at £608 on average.

How far in advance should I book a flight from Madrid to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Santiago, you should book around 13 weeks before departure, which saves you about 16% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Santiago

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on Iberia and LATAM Airlines

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Good to know - Cheap tickets from Madrid to Santiago

Low seasonJune
Cheapest flight£371
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly (18% more expensive on average)
Flight from Madrid to Santiago

When to book flights from Madrid to Santiago

Are your dates flexible? Find out the best times to travel from Madrid to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santiago

  • What is the cheapest flight from Madrid to Santiago?

    In the last 3 days, the lowest price for a flight from Madrid to Santiago was £371 for a one-way ticket and £641 for a return.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santiago?

    Iberia, Qatar Airways, LATAM Airlines, Vueling, and Aerolineas Argentinas offer inflight Wi-Fi service on the Madrid to Santiago flight route.

  • Which aircraft models fly most regularly from Madrid to Santiago?

    The Airbus A350-900 is the aircraft model that flies most regularly on the Madrid to Santiago flight route.

  • Which airline alliances offer flights from Madrid to Santiago?

    oneworld is the only airline alliance operating flights between Madrid and Santiago.

  • On which days can I fly direct from Madrid to Santiago?

    There are direct flights from Madrid to Santiago on a daily basis.

  • Which is the best airline for flights from Madrid to Santiago, LATAM Airlines or Iberia?

    The two airlines most popular with KAYAK users for flights from Madrid to Santiago are LATAM Airlines and Iberia. With an average price for the route of £1,098 and an overall rating of 7.4, LATAM Airlines is the most popular choice. Iberia is also a great choice for the route, with an average price of £911 and an overall rating of 7.0.

  • How does KAYAK find such low prices on flights from Madrid to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Santiago with an airline and back to Madrid with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Santiago

  • Looking for a cheap flight from Madrid to Santiago? 25% of our users found flights on this route for £612 or less one-way and £959 or less round-trip.

Prefer to fly direct from Madrid to Santiago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Santiago Arturo Merino Benitez.
Find which airlines fly direct from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santiago Arturo Merino Benitez

Monday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Tuesday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Wednesday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Thursday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Friday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Saturday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Sunday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Madrid Barajas

Monday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Tuesday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Wednesday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Thursday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Friday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Saturday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

Sunday

Iberia,LATAM Airlines

Iberia,LATAM Airlines

See more direct flights

Reviews of the top airlines flying from Madrid to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1911 reviews
8.0Crew
7.3Comfort
7.5Boarding
7.0Entertainment
6.7Food
Airline reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

10.0 ExcellentYelen, Mar 2026
ATL - TPA
Read more LATAM Airlines reviews

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

Good check in process Poor information on payments at Lima airport

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor, the airline was not able to help me move flights.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Excellent crew, food and service. Boarding via bus is always a pain but overall really good

Stewardess was not attentive at all asked for a bottle of water never came by 15 minutes later I asked her she said that she forgot there was only 12 people in first class and two stewardess unacceptable I ordered the fish was the last person to order. They said that they did not have any had to have a different item pasta at the inside of it because I was diabetic. Worst experience I ever had will never travel this airline again.

It’s got the tightest seats of any airline - my knees were smashed for 3 hours - absolutely awful.

Flight was fine - however my husband's checked in case was damaged, and mine still has not arrived

30 minutes still don't have gate number, ask many people can't get answer.

The boarding procedure got confusing because they wanted to weigh everyone’s carry-on. Apparently mine was 3 1/2 kg over their limit. I didn’t know they had a limit. And at the check-in desk, nothing was said about this. They wanted me to check the carry-on at no charge and that would have been fine except then they told me at my connection in London I would have to go outside to baggage claim retrieve my bag, and then recheck it. In other words, they could not check it to my final destination, only to London. I told him this was unacceptable so after a few minutes of discussion, they came back and said that my bag would be OK to carry on the plane. It seems that if you have a connection then the weight is not as important. Then when I actually went to board the boarding agent said I needed a tag indicating that my bag had been weighed, even though she had just five minutes ago talked to the same person who cleared me. Lots of confusion seems like a very bad process. They need to improve this.

The crew was super friendly and helpful. The food was quite good. An overall positive experience.

the seats were bad and uncomfortable and the food was not tasty.

The crew was amazing. I appreciate the level of professionalism in the Iberia crew.

A more organized boarding experience and better food would have made the experience better.

Everything you need to know for your flight from Madrid to Santiago

Information on your arrival and departure airports