£231 Find Cheap Flights from Panama City to Santiago – Compare and Save

These are the earliest and latest flight times available from Panama City to Santiago:

• Earliest: departs at 11:48 and lands at 18:17
• Latest: departs at 21:39 and lands at 04:08.

The flight takes about 6h 29m.

A direct flight from Panama City to Santiago takes 6h 29m, covering 2,986 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Return flights from Panama City to Santiago range from £428 to £524, with an average of £482 over the past 12 months. Anything below £428 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 5% above the £482 route average. Book 6 weeks before departure for the lowest fares.

On this route, direct and stopover fares are close on average, with direct at £486 return and stopover options via Bogotá El Dorado (BOG) at £473.

Copa Airlines is the only airline operating Panama City to Santiago flights. 90% of its flights are on time.

There is no standard. Checked bag policies vary by airline on this route. Most carriers charge £75–£75 for the first checked bag in Economy. Premium fares and elite status bookings typically include a free checked bag.

The Boeing 737 MAX 9 family is used most often on this route, operated mainly by Copa Airlines. Other aircraft seen on the route include Boeing 737 MAX 8 variants.

Afternoon is the busiest departure period on Panama City to Santiago flights, with 34% leaving in that window. Evening departures account for 33%, Morning flights for 17%, and Night flights for 16%.

Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about £453 to £2,313. That means the highest observed fare was about 5x higher than the lowest one.

One-way fares from Panama City to Santiago are currently higher than usual. Average one-way flight prices are about £291, which is 5% above the typical average for this route.

Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car hire companies, with daily rates starting from around £4 for economy cars. Top options include:

• Lucano
• United Rent-A-Car
• Rosselot
• FlexWays
• Alamo

Flights from Panama City to Santiago usually depart from Panama City Tocumen Intl (PTY) and arrive at Santiago Arturo Merino Benitez (SCL).

Night flights have the fewest delays on this route, while afternoon departures tend to have the most.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Panama City to Santiago route, 10% of flights were delayed in the past three months, with delays averaging 1h 56m.

One-stop flights from Panama City to Santiago most commonly connect through:

• Bogotá El Dorado (BOG) – 100% of one-stop connections
• Lima J Chavez Intl (LIM) – 0% of one-stop connections
• Miami (MIA) – 0% of one-stop connections

Yes. Flexible dates can save you up to 6% on flights from Panama City to Santiago. Tuesday is the cheapest departure day at £462 return on average, while Sunday is the most expensive at £491, a difference of £28.

KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

Only Copa Airlines operates flights between Panama City and Santiago.

Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time of 9h 48m, compared to 13h 01m via Lima J Chavez Intl (LIM) and 17h 12m via Miami (MIA).

Santiago is 2 hours ahead of Panama City (Chile Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Museum of Contemporary Art is one of the most viewed places in Santiago on KAYAK.

Among airlines operating Panama City to Santiago flights:

• Copa Airlines: offers extra legroom; offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a cabin bag and a checked bag in Economy class

Baggage allowance can vary by ticket type, cabin class, route, and airline, so always check the fare details before booking.