£446 Find Cheap Flights from San Francisco to Santiago – Compare and Save

Only Economy class is available on flights from San Francisco to Santiago.

A direct flight from San Francisco to Santiago takes 00m, covering 5,918 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Return flights from San Francisco to Santiago range from £534 to £820, with an average of £651 over the past 12 months. Anything below £534 counts as a good deal.

Last-minute fares on this route (booked within two weeks of departure) run 21% above the £651 route average. Book 18 weeks before departure for the lowest fares.

Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about £677 to £4,171. That means the highest observed fare was about 6x higher than the lowest one.

One-way fares from San Francisco to Santiago are currently higher than usual. Average one-way flight prices are about £533, which is 43% above the typical average for this route.

Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car hire companies, with daily rates starting from around £5 for economy cars. Top options include:

• Lucano
• United Rent-A-Car
• Rosselot
• FlexWays
• Alamo

Flights from San Francisco to Santiago usually depart from San Francisco (SFO) and arrive at Santiago Arturo Merino Benitez (SCL).

One-stop flights from San Francisco to Santiago most commonly connect through:

• Los Angeles (LAX) – 30% of one-stop connections
• Houston George Bush Intcntl (IAH) – 27% of one-stop connections
• Panama City Tocumen Intl (PTY) – 19% of one-stop connections
• Miami (MIA) – 9% of one-stop connections

Yes. Flexible dates can save you up to 13% on flights from San Francisco to Santiago. Wednesday is the cheapest departure day at £616 return on average, while Saturday is the most expensive at £705, a difference of £88.

KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

Flying via Los Angeles (LAX) gives the shortest average 1-stop total travel time of 15h 15m, compared to 15h 41m via Panama City Tocumen Intl (PTY) and 16h 23m via Dallas/Fort Worth (DFW).

Santiago is 4 hours ahead of San Francisco (Chile Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

Museum of Contemporary Art is one of the most viewed places in Santiago on KAYAK.

A visa is not one of the mandatory requirements for US citizens traveling to Chile as long as the trip doesn’t exceed 90 days. If so, you will have to visit the Chilean Embassy for further inquiry. You will also need your passport which should be valid up to the point of planned departure from Chile.

At the moment, there aren’t any airlines flying directly from San Francisco to the city center. Travelers will have to deal with at least one layover during the trip. The most popular layover option for this trip is Los Angeles International Airport which is used by Delta and LATAM Airlines. Other options include Houston when flying with United Airlines and Panama City when flying with Copa Airlines.

The only public transport option available from Santiago International Airport to the city center is the bus service. It runs 24/7 at intervals of 20 minutes during the day and an hour after midnight. The bus connects Santiago Airport to Santiago Central Station although you can disembark at any of the prior stops if it is convenient for you. An alternative to using the bus is getting a taxi from the airport. Although more expensive, it is significantly more convenient and safer than public transport.

LATAM Airlines has an unaccompanied minor service that allows children to fly unaccompanied on international flights. The service is mandatory for children between ages 8 and 12 and only optional for children older than that. With this service, you as the parent can have confidence in the safety of your child as they will have a crew member looking after your child for the whole trip including through immigration and security control.