SDQ - SCL

£241 Find Cheap Flights from Santo Domingo to Santiago – Compare and Save

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Everything you should know

Cheapest return flight
£644
Typical prices: £485-£614
Multiple Airlines
Sat 17/11Sun 25/11
SDQ - SCL • 1 stop
Cheapest one-way flight
£241
Typical prices: £254-£335
Multiple Airlines
Thu 15/11
SDQ - SCL • 1 stop
Direct flights
Not available
There are currently no direct flights between Santo Domingo and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
26 weeks
in advance
Our data shows that travellers who book at least 26 weeks in advance save around 30% compared to booking last minute.
Insights
Insights
When to travel
March
Cheapest • 5% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Punta Cana (PUJ)
Cheapest • Avg £422 (return)
Bogotá El Dorado (BOG)
Shortest trip • 11h 16m (one-way)
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Insights
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We hope you enjoy your trip to Santiago!
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Flight Deals

Cheap Flights from Santo Domingo to Santiago (SDQ-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Santo Domingo to Santiago

Tue, 17 Nov - Wed, 25 Nov
Multiple Airlines Logo
13:40 - 03:35SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
12h 55m1 stop Punta Cana
Multiple Airlines Logo
05:00 - 16:20SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
12h 20m1 stop Punta Cana
£644Multiple Airlines
Fri, 20 Nov - Fri, 27 Nov
Copa Airlines Logo
19:06 - 00:24SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
28h 18m1 stop Panama City Tocumen Intl
Copa Airlines Logo
03:48 - 02:08SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
23h 20m1 stop Panama City Tocumen Intl
£678Copa Airlines
Thu, 10 Dec - Wed, 16 Dec
Copa Airlines Logo
05:53 - 20:11SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
13h 18m1 stop Panama City Tocumen Intl
Copa Airlines Logo
03:48 - 22:58SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
20h 10m1 stop Panama City Tocumen Intl
£699Copa Airlines
Sat, 27 Feb - Sat, 1 May
Copa Airlines Logo
12:42 - 05:59SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
16h 17m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:30 - 22:22SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
10h 52m1 stop Panama City Tocumen Intl
£729Copa Airlines
Fri, 20 Nov - Fri, 27 Nov
Copa Airlines Logo
12:45 - 00:24SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
10h 39m1 stop Panama City Tocumen Intl
Copa Airlines Logo
03:48 - 13:10SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
10h 22m1 stop Panama City Tocumen Intl
£756Copa Airlines
Mon, 7 Dec - Sun, 27 Dec
Copa Airlines Logo
19:03 - 20:11SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
24h 08m1 stop Panama City Tocumen Intl
Copa Airlines Logo
01:07 - 16:13SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
16h 06m1 stop Panama City Tocumen Intl
£770Copa Airlines
Mon, 21 Dec - Mon, 28 Dec
Copa Airlines Logo
12:43 - 00:23SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
10h 40m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:20 - 02:08SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
14h 48m1 stop Panama City Tocumen Intl
£814Copa Airlines
Wed, 25 Nov - Wed, 2 Dec
United Airlines Logo
16:18 - 08:50SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
39h 32m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
22:45 - 23:46SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
26h 01m2 stops Houston George Bush Intcntl Newark
£1,109United Airlines
Fri, 27 Nov - Tue, 1 Dec
United Airlines Logo
16:18 - 08:50SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
39h 32m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
22:45 - 23:46SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
50h 01m2 stops Houston George Bush Intcntl Newark
£1,145United Airlines
Fri, 27 Nov - Tue, 1 Dec
United Airlines Logo
16:18 - 08:50SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
39h 32m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
22:45 - 13:41SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
39h 56m2 stops Houston George Bush Intcntl Newark
£1,158United Airlines
Booking Insights

Price, demand, and travel trends for Santo Domingo to Santiago flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights with more confidence.

What's the cheapest day of the week to fly from Santo Domingo to Santiago?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Santo Domingo to Santiago. It's 5% cheaper than the average day, while Friday is the most expensive, with prices 8% higher.

What is the cheapest month to fly from Santo Domingo to Santiago?

•March is the cheapest month to fly from Santo Domingo to Santiago at £519 return.
•January (£589) and December (£587) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 13% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Santo Domingo to Santiago the cheapest?

Flights from Santo Domingo to Santiago are cheapest 26 weeks before departure. Booking in this window typically costs about 30% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Santo Domingo to Santiago flights

Low season

February

Cheapest flight

£241
Beat the crowds with an average 20% drop in traveller numbers.
The most popular month to fly with an average 39% increase in traveller numbers.
One-way flight from Santo Domingo to Santiago

When to book flights from Santo Domingo to Santiago

Are your dates flexible? Find out the best times to travel from Santo Domingo to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Santo Domingo to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines, and booking tips.

  • How long is a flight from Santo Domingo to Santiago?

    A direct flight from Santo Domingo to Santiago takes 00m, covering 3,579 miles.

  • Do I need a passport to fly from Santo Domingo to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Santo Domingo to Santiago flight?

    Return flights from Santo Domingo to Santiago range from £485 to £614, with an average of £546 over the past 12 months. Anything below £485 counts as a good deal.

  • How expensive are last-minute Santo Domingo to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 9% above the £546 route average. Book 26 weeks before departure for the lowest fares.

  • How are flight prices from Santo Domingo to Santiago looking right now?

    One-way fares from Santo Domingo to Santiago are currently higher than usual. Average one-way flight prices are about £536, which is 84% above the typical average for this route.

  • Which car hire options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car hire companies, with daily rates starting from around £27 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Santo Domingo to Santiago?

    Flights from Santo Domingo to Santiago usually depart from Santo Domingo Las Americas (SDQ) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airports do connecting flights from Santo Domingo to Santiago pass through?

    One-stop flights from Santo Domingo to Santiago most commonly connect through:

    • Panama City Tocumen Intl (PTY) – 42% of one-stop connections
    • Bogotá El Dorado (BOG) – 41% of one-stop connections
    • Punta Cana (PUJ) – 11% of one-stop connections
    • Lima J Chavez Intl (LIM) – 5% of one-stop connections

  • Can I save money by using flexible dates for flights from Santo Domingo to Santiago?

    Yes. Flexible dates can save you up to 12% on flights from Santo Domingo to Santiago. Thursday is the cheapest departure day at £522 return on average, while Friday is the most expensive at £590, a difference of £67.

    KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different stopover airport from Santo Domingo to Santiago?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time of 11h 16m, compared to 11h 20m via Panama City Tocumen Intl (PTY) and 12h 32m via Punta Cana (PUJ).

  • What is the time difference between Santo Domingo and Santiago?

    Santiago is 1 hour ahead of Santo Domingo (Chile Time vs Atlantic Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Museum of Contemporary Art is one of the most viewed places in Santiago on KAYAK.

Your guide to booking Santo Domingo to Santiago flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Friday. On this route, Thursday flights average £522, about £67 less than Friday fares (11% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 26 weeks before you fly. On this route, that window historically saves about 30% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Santo Domingo to Santiago trip for March. Fares historically average £519 return in that month – typically £70 less than the most expensive month, which is January (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

More options for your flight from Santo Domingo to Santiago

Complete your trip to Santiago with a hotel stay or car hire

Car hire in Santiago
Hotels in Santiago
Holidays in Santiago