SDQ - SCL

£179 Find Cheap Flights from Santo Domingo to Santiago – Compare and Save

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Everything you should know

Cheapest return flight
£420
Typical prices: £468-£605
Multiple Airlines
Thu 15/11Fri 30/11
SDQ - SCL • 1 stop
Cheapest one-way flight
£179
Typical prices: £245-£329
Multiple Airlines
Tue 9/10
SDQ - SCL • 1 stop
Direct flights
Not available
There are currently no direct flights between Santo Domingo and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
26 weeks
in advance
Our data shows that travellers who book at least 26 weeks in advance save around 35% compared to booking last minute.
Insights
Insights
When to travel
September
Cheapest • 11% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Punta Cana (PUJ)
Cheapest • Avg £415 (return)
Bogotá El Dorado (BOG)
Shortest trip • 11h 14m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Santiago (SDQ-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Santo Domingo to Santiago

Sun, 15 Nov - Mon, 30 Nov
Multiple Airlines Logo
15:55 - 04:55SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
12h 00m1 stop Punta Cana
Multiple Airlines Logo
06:00 - 16:45SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 45m1 stop Punta Cana
£420Multiple Airlines
Fri, 2 Oct - Mon, 12 Oct
Multiple Airlines Logo
08:55 - 23:55SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
14h 00m1 stop Punta Cana
Multiple Airlines Logo
06:00 - 16:55SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 55m1 stop Punta Cana
£453Multiple Airlines
Sun, 1 Nov - Sat, 7 Nov
Multiple Airlines Logo
15:55 - 04:55SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
12h 00m1 stop Punta Cana
Multiple Airlines Logo
09:25 - 21:40SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
13h 15m1 stop Punta Cana
£515Multiple Airlines
Sun, 1 Nov - Sat, 7 Nov
Copa Airlines Logo
08:55 - 23:36SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
13h 41m1 stop Panama City Tocumen Intl
Copa Airlines Logo
05:07 - 16:12SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
12h 05m1 stop Panama City Tocumen Intl
£569Copa Airlines
Tue, 1 Dec - Wed, 30 Dec
Multiple Airlines Logo
13:40 - 03:35SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
12h 55m1 stop Punta Cana
Multiple Airlines Logo
05:00 - 16:20SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
12h 20m1 stop Punta Cana
£571Multiple Airlines
Thu, 8 Oct - Tue, 13 Oct
Copa Airlines Logo
12:12 - 23:39SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
10h 27m1 stop Panama City Tocumen Intl
Copa Airlines Logo
05:22 - 16:14SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 52m1 stop Panama City Tocumen Intl
£669Copa Airlines
Thu, 10 Dec - Sun, 27 Dec
Copa Airlines Logo
12:09 - 02:48SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
13h 39m1 stop Panama City Tocumen Intl
Copa Airlines Logo
03:19 - 02:08SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
23h 49m1 stop Panama City Tocumen Intl
£671Copa Airlines
Tue, 15 Dec - Wed, 23 Dec
Copa Airlines Logo
14:14 - 05:52SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
14h 38m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:20 - 11:42SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
24h 22m1 stop Panama City Tocumen Intl
£689Copa Airlines
Thu, 10 Dec - Mon, 28 Dec
Copa Airlines Logo
12:09 - 05:52SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
16h 43m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:20 - 02:08SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
14h 48m1 stop Panama City Tocumen Intl
£719Copa Airlines
Mon, 26 Oct - Mon, 2 Nov
United Airlines Logo
05:00 - 07:50SDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
25h 50m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
22:45 - 13:41SCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
39h 56m2 stops Houston George Bush Intcntl Newark
£1,000United Airlines
Booking Insights

Price, demand, and travel trends for Santo Domingo to Santiago flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights from Santo Domingo to Santiago with more confidence.

What's the cheapest day of the week to fly from Santo Domingo to Santiago?

Thursday is the cheapest day of the week to fly from Santo Domingo to Santiago and is 5% cheaper than the average day. Friday is the most expensive day with flight prices 7% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Santo Domingo to Santiago?

•September is the cheapest month to fly from Santo Domingo to Santiago at £479 return.
•January (£588) and August (£585) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 22% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Santo Domingo to Santiago the cheapest?

Flights from Santo Domingo to Santiago are cheapest 26 weeks before departure. Booking in this window typically costs about 35% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Santo Domingo to Santiago flights

Low season

February

Cheapest flight

£179
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flights from Santo Domingo to Santiago

When to book flights from Santo Domingo to Santiago

Are your dates flexible? Find out the best times to travel from Santo Domingo to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Santo Domingo to Santiago flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines, and booking questions.

  • Which airports can I use when flying from Santo Domingo to Santiago?

    Flights from Santo Domingo to Santiago usually depart from Santo Domingo Las Americas (SDQ) and arrive at Santiago Arturo Merino Benitez (SCL).

  • How much can I save by having a stopover when flying from Santo Domingo to Santiago?

    On this route, direct and stopover fares are close on average, with direct at £423 return and stopover options via Punta Cana (PUJ) at £415.

  • Which airports do connecting flights from Santo Domingo to Santiago pass through?

    One-stop flights from Santo Domingo to Santiago most commonly connect through:

    • Bogotá El Dorado (BOG) – 44% of one-stop connections
    • Panama City Tocumen Intl (PTY) – 42% of one-stop connections
    • Punta Cana (PUJ) – 9% of one-stop connections
    • Lima J Chavez Intl (LIM) – 5% of one-stop connections

    Bogotá El Dorado (BOG) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Santo Domingo to Santiago?

    Yes. Being flexible with your travel dates can save you up to 12% on the Santo Domingo to Santiago route. Thursday is the cheapest departure day at £517 return on average, while Friday is the most expensive at £582, a difference of £65. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Santiago?

    Museum of Contemporary Art is one of the most viewed places in Santiago on KAYAK.

  • How expensive are last-minute Santo Domingo to Santiago flights?

    Last-minute fares on this route (booked within 2 weeks of departure) run 17% above the route average of £540. Book 26 weeks before departure for the lowest fares.

  • How long is a flight from Santo Domingo to Santiago?

    A direct flight from Santo Domingo to Santiago takes 0h 00m, covering 3,579 miles.

  • Do I need a passport to fly from Santo Domingo to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How are flight prices from Santo Domingo to Santiago looking right now?

    One-way fares from Santo Domingo to Santiago are currently higher than usual. Average one-way flight prices are about £764, which is 172% above the typical average for this route.

  • How much time can I save by choosing a different stopover airport from Santo Domingo to Santiago?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time of 11h 14m, compared to 11h 22m via Panama City Tocumen Intl (PTY) and 12h 36m via Punta Cana (PUJ).

  • What is the time difference between Santo Domingo and Santiago?

    Santiago is 1 hour ahead of Santo Domingo (Chile Time vs Atlantic Time). Plan for the time shift when scheduling connections or first-day activities.

  • Which car hire options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car hire companies, with daily rates starting from around £4 for economy cars. Top options include:
    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • How much should I expect to pay for a Santo Domingo to Santiago flight?

    Return flights from Santo Domingo to Santiago range from £468 to £605, with an average of £540 over the past 12 months. Anything below £468 counts as a good deal.

Your guide to booking Santo Domingo to Santiago flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure instead of Friday. On this route, Thursday flights average £517 – about £65 less than Friday (11% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 26 weeks before you fly. On this route, that window historically saves about 35% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Santo Domingo to Santiago trip for September. Fares historically average £479 return in that month – typically £108 less than the most expensive month, which is January (based on the last 12 months).
  • If you have the time, taking a 1-stop flight through Punta Cana Airport (PUJ) can be cheaper than flying direct. The cheapest stopover option averages £415 return on this route – about £8 less than direct flights (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.
    - Holiday Inn Santiago - Airport Terminal By IHG

More options for your flight from Santo Domingo to Santiago

Complete your trip to Santiago with a hotel stay or car hire

Car hire in Santiago
Hotels in Santiago
Holidays in Santiago