SOU - PTY

£1,038 Find Cheap Flights from Southampton to Panama City – Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest return flight
£1,038
Typical prices: £554-£1,590
KLM
Mon 10/12Mon 17/12
SOU - PTY • 1 stop
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Flight Deals

Cheap Flights from Southampton to Panama City (SOU-PTY)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Southampton to Panama City

Thu, 10 Dec - Thu, 17 Dec
KLM Logo
17:35 - 16:30SOU  Southampton Eastleigh-PTY Panama City Tocumen Intl
27h 55m1 stop Amsterdam Schiphol
KLM Logo
21:48 - 08:55PTY  Panama City Tocumen Intl-SOU Southampton Eastleigh
54h 07m2 stops Port of Spain Piarco Intl Amsterdam Schiphol
£1,038KLM
Thu, 10 Dec - Thu, 17 Dec
Multiple Airlines Logo
14:25 - 20:20SOU  Southampton Eastleigh-PTY Panama City Tocumen Intl
34h 55m2 stops Geneva Geneve-Cointrin Paris Charles de Gaulle
Multiple Airlines Logo
22:30 - 06:45PTY  Panama City Tocumen Intl-SOU Southampton Eastleigh
27h 15m2 stops Paris Charles de Gaulle Geneva Geneve-Cointrin
£1,041Multiple Airlines
Thu, 10 Dec - Thu, 17 Dec
KLM Logo
17:35 - 19:55SOU  Southampton Eastleigh-PTY Panama City Tocumen Intl
31h 20m1 stop Amsterdam Schiphol
KLM Logo
18:45 - 17:05PTY  Panama City Tocumen Intl-SOU Southampton Eastleigh
17h 20m1 stop Amsterdam Schiphol
£1,131KLM
Thu, 10 Dec - Wed, 16 Dec
Multiple Airlines Logo
08:40 - 05:48SOU  Southampton Eastleigh-PTY Panama City Tocumen Intl
50h 08m3 stops Amsterdam Schiphol Simpson Bay Princess Juliana Port of Spain Piarco Intl
Multiple Airlines Logo
02:30 - 14:10PTY  Panama City Tocumen Intl-SOU Southampton Eastleigh
30h 40m2 stops Bogotá El Dorado Barcelona-El Prat
£1,262Multiple Airlines
Thu, 10 Dec - Thu, 17 Dec
Multiple Airlines Logo
08:40 - 20:20SOU  Southampton Eastleigh-PTY Panama City Tocumen Intl
40h 40m3 stops Amsterdam Schiphol Geneva Geneve-Cointrin Paris Charles de Gaulle
Multiple Airlines Logo
22:30 - 08:55PTY  Panama City Tocumen Intl-SOU Southampton Eastleigh
53h 25m3 stops Paris Charles de Gaulle Geneva Geneve-Cointrin Amsterdam Schiphol
£1,355Multiple Airlines
Booking Insights

Price, demand, and travel trends for Southampton to Panama City flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights with more confidence.

How much is a return flight from Southampton to Panama City?

Return flights from Southampton to Panama City typically range from £554 to £1,590. The lowest price found in the past 5 days was £1,038 on KLM.

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Key details for Southampton to Panama City flights

Cheapest flight

£1,038
Round-trip flight from Southampton to Panama City

When to book flights from Southampton to Panama City

Are your dates flexible? Find out the best times to travel from Southampton to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Southampton to Panama City flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines, and booking tips.

  • Do I need a passport to fly from Southampton to Panama City?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Southampton to Panama City changed much recently?

    Yes. Based on fares seen in the past 5 days, return prices on this route varied from about £1,038 to £1,355. That means the highest observed fare was about 30% higher than the lowest one.

  • Which car hire options are available at Panama City Tocumen Intl Airport (PTY)?

    Panama City Tocumen Intl Airport (PTY) hosts 5 major car hire companies, with daily rates starting from around £1 for economy cars. Top options include:

    • Avis
    • Ace
    • Europcar
    • Budget
    • Thrifty

  • Which airports can I use when flying from Southampton to Panama City?

    Flights from Southampton to Panama City usually depart from Southampton Eastleigh (SOU) and arrive at Panama City Tocumen Intl (PTY).

  • Which airports do connecting flights from Southampton to Panama City pass through?

    Most connecting flights from Southampton to Panama City pass through Amsterdam Schiphol (AMS), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from Southampton to Panama City?

    Yes. Flexible dates can save you up to 66% on flights from Southampton to Panama City. Tuesday is the cheapest departure day at £554 return on average, while Monday is the most expensive at £1,589, a difference of £1,035.

    KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between Southampton and Panama City?

    Panama City is 5 hours behind Southampton (Eastern Time vs British Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Southampton to Panama City flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Monday. On this route, Tuesday flights average £554, about £1,035 less than Monday fares (65% savings) based on the last 12 months.
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City Tocumen Intl Airport.

    • Riande Aeropuerto Hotel & Casino

More options for your flight from Southampton to Panama City

Complete your trip to Panama City with a hotel stay or car hire

Car hire in Panama City
Hotels in Panama City
Holidays in Panama City