BRU - PTY

£471 Find Cheap Flights from Brussels to Panama City – Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest return flight
£549
Typical prices: £550-£716
KLM
Fri 23/11Thu 6/12
BRU - PTY • 1 stop
Cheapest one-way flight
£471
Typical prices: £283-£456
Multiple Airlines
Thu 25/1
BRU - PTY • 2 stops
Direct flights
Not available
There are currently no direct flights between Brussels Bruxelles-National Airport and Panama City. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
7 weeks
in advance
Our data shows that travellers who book at least 7 weeks in advance save around 20% compared to booking last minute.
Insights
Insights
When to travel
November
Cheapest • 11% price drop
July
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Frankfurt am Main (FRA)
Cheapest • Avg £584 (return)
Amsterdam Schiphol (AMS)
Shortest trip • 13h 56m (one-way)
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Insights
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We hope you enjoy your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Brussels to Panama City (BRU-PTY)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Brussels to Panama City

Mon, 23 Nov - Sun, 6 Dec
KLM Logo
06:15 - 16:30BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
16h 15m1 stop Amsterdam Schiphol
KLM Logo
18:45 - 14:15PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
13h 30m1 stop Amsterdam Schiphol
£549KLM
Mon, 23 Nov - Sun, 6 Dec
KLM Logo
06:15 - 16:30BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
16h 15m1 stop Amsterdam Schiphol
KLM Logo
22:30 - 22:20PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
17h 50m2 stops Paris Charles de Gaulle Amsterdam Schiphol
£563KLM
Sat, 21 Nov - Fri, 4 Dec
KLM Logo
10:45 - 05:48BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
25h 03m3 stops Amsterdam Schiphol Simpson Bay Princess Juliana Port of Spain Piarco Intl
KLM Logo
21:55 - 22:20PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
18h 25m1 stop Amsterdam Schiphol
£589KLM
Wed, 27 Jan - Sat, 30 Jan
United Airlines Logo
10:30 - 14:45BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
34h 15m2 stops Frankfurt am Main Houston George Bush Intcntl
United Airlines Logo
10:00 - 08:05PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
16h 05m1 stop Newark
£606United Airlines
Sun, 22 Nov - Sun, 6 Dec
United Airlines Logo
11:15 - 14:45BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
33h 30m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
11:35 - 07:15PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
37h 40m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl
£608United Airlines
Wed, 27 Jan - Mon, 1 Feb
United Airlines Logo
10:30 - 14:45BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
34h 15m2 stops Frankfurt am Main Houston George Bush Intcntl
United Airlines Logo
10:00 - 13:15PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
21h 15m2 stops Newark London Heathrow
£609United Airlines
Sat, 21 Nov - Fri, 4 Dec
United Airlines Logo
11:15 - 19:38BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
38h 23m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
10:00 - 08:50PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
40h 50m2 stops Newark London Heathrow
£609United Airlines
Mon, 25 Jan - Mon, 1 Feb
United Airlines Logo
09:30 - 20:02BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
40h 32m2 stops Zurich Newark
United Airlines Logo
10:00 - 08:05PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
16h 05m1 stop Newark
£610United Airlines
Thu, 28 Jan - Sat, 13 Feb
United Airlines Logo
11:15 - 17:12BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
35h 57m2 stops Newark Houston George Bush Intcntl
United Airlines Logo
16:41 - 07:15PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
32h 34m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl
£612United Airlines
Sat, 27 Feb - Sat, 20 Mar
United Airlines Logo
09:30 - 20:02BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
40h 32m2 stops Zurich Newark
United Airlines Logo
22:55 - 13:15PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
32h 20m2 stops Newark London Heathrow
£612United Airlines
Booking Insights

Price, demand, and travel trends for Brussels Bruxelles-National Airport to Panama City flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights with more confidence.

How much is a return flight from Brussels Bruxelles-National Airport to Panama City?

Return flights from Brussels Bruxelles-National Airport to Panama City typically range from £550 to £716. The lowest price found in the past 5 days was £549 on KLM.

What's the cheapest day of the week to fly from Brussels Bruxelles-National Airport to Panama City?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Brussels Bruxelles-National Airport to Panama City. It's 4% cheaper than the average day, while Sunday is the most expensive, with prices 8% higher.

What is the cheapest month to fly from Brussels Bruxelles-National Airport to Panama City?

•November is the cheapest month to fly from Brussels Bruxelles-National Airport to Panama City at £537 return.
•December (£774) and May (£732) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 44% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Brussels Bruxelles-National Airport to Panama City the cheapest?

Flights from Brussels Bruxelles-National Airport to Panama City are cheapest 7 weeks before departure. Booking in this window typically costs about 20% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Brussels Bruxelles-National Airport to Panama City flights

Low season

October

Cheapest flight

£471
Beat the crowds with an average 61% drop in traveller numbers.
The most popular month to fly with an average 66% increase in traveller numbers.
One-way flight from Brussels Bruxelles-National Airport to Panama City

When to book flights from Brussels to Panama City

Are your dates flexible? Find out the best times to travel from Brussels to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Brussels Bruxelles-National Airport to Panama City flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines, and booking tips.

  • Which cabin classes can I book on flights from Brussels Bruxelles-National Airport to Panama City?

    Only Business Class is available on flights from Brussels Bruxelles-National Airport to Panama City.

  • How long is a flight from Brussels Bruxelles-National Airport to Panama City?

    A direct flight from Brussels Bruxelles-National Airport to Panama City takes 00m, covering 5,462 miles.

  • Do I need a passport to fly from Brussels Bruxelles-National Airport to Panama City?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Brussels Bruxelles-National Airport to Panama City flight?

    Return flights from Brussels Bruxelles-National Airport to Panama City range from £550 to £716, with an average of £605 over the past 12 months. Anything below £550 counts as a good deal.

  • How expensive are last-minute Brussels Bruxelles-National Airport to Panama City flights?

    Last-minute fares on this route (booked within two weeks of departure) run 20% above the £605 route average. Book 7 weeks before departure for the lowest fares.

  • Have flight prices from Brussels Bruxelles-National Airport to Panama City changed much recently?

    Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about £549 to £3,258. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Brussels Bruxelles-National Airport to Panama City looking right now?

    One-way fares from Brussels Bruxelles-National Airport to Panama City are currently higher than usual. Average one-way flight prices are about £1,053, which is 172% above the typical average for this route.

  • Which car hire options are available at Panama City Tocumen Intl Airport (PTY)?

    Panama City Tocumen Intl Airport (PTY) hosts 5 major car hire companies, with daily rates averaging £12 for economy cars. Top options include:

    • Avis
    • Ace
    • Europcar
    • Budget
    • Thrifty

  • Which airports can I use when flying from Brussels Bruxelles-National Airport to Panama City?

    Flights from Brussels Bruxelles-National Airport to Panama City usually depart from Brussels Bruxelles-National (BRU) and arrive at Panama City Tocumen Intl (PTY).

  • Which airports do connecting flights from Brussels Bruxelles-National Airport to Panama City pass through?

    One-stop flights from Brussels Bruxelles-National Airport to Panama City most commonly connect through:

    • Madrid Barajas (MAD) – 55% of one-stop connections
    • Newark (EWR) – 31% of one-stop connections
    • Amsterdam Schiphol (AMS) – 9% of one-stop connections
    • Washington, D.C. Dulles Intl (IAD) – 4% of one-stop connections

  • Can I save money by using flexible dates for flights from Brussels Bruxelles-National Airport to Panama City?

    Yes. Flexible dates can save you up to 12% on flights from Brussels Bruxelles-National Airport to Panama City. Wednesday is the cheapest departure day at £582 return on average, while Sunday is the most expensive at £658, a difference of £76.

    KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different stopover airport from Brussels Bruxelles-National Airport to Panama City?

    Flying via Amsterdam Schiphol (AMS) gives the shortest average 1-stop total travel time of 13h 56m, compared to 15h 29m via Madrid Barajas (MAD) and 15h 50m via Washington, D.C. Dulles Intl (IAD).

  • What is the time difference between Brussels Bruxelles-National Airport and Panama City?

    Panama City is 6 hours behind Brussels Bruxelles-National Airport (Eastern Time vs Central European Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Brussels Bruxelles-National Airport to Panama City flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Sunday. On this route, Wednesday flights average £582, about £76 less than Sunday fares (12% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 7 weeks before you fly. On this route, that window historically saves about 20% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Brussels Bruxelles-National Airport to Panama City trip for November. Fares historically average £537 return in that month – typically £238 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City Tocumen Intl Airport.

    • Riande Aeropuerto Hotel & Casino

More options for your flight from Brussels to Panama City

Complete your trip to Panama City with a hotel stay or car hire

Car hire in Panama City
Hotels in Panama City
Holidays in Panama City