PTY - BRU

£726 Find Cheap Flights from Panama City to Brussels – Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest return flight
£726
Typical prices: £661-£863
Turkish Airlines
Wed 28/2Sun 4/3
PTY - BRU • 1 stop
Cheapest one-way flight
£792
Typical prices: £487-£622
Turkish Airlines
Tue 16/1
PTY - BRU • 1 stop
Direct flights
Not available
There are currently no direct flights between Panama City and Brussels Bruxelles-National Airport. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 14% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Istanbul (IST)
Cheapest • Avg £708 (return)
Amsterdam Schiphol (AMS)
Shortest trip • 14h 49m (one-way)
Insights
Insights
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We hope you enjoy your trip to Brussels Bruxelles-National Airport!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Brussels (PTY-BRU)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Panama City to Brussels

Sun, 28 Feb - Thu, 4 Mar
Turkish Airlines Logo
18:50 - 22:20PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
21h 30m1 stop Istanbul
Turkish Airlines Logo
15:15 - 20:05BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
34h 50m1 stop Istanbul
£726Turkish Airlines
Sun, 28 Feb - Thu, 4 Mar
Air Europa Logo
21:30 - 09:50PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
30h 20m1 stop Madrid Barajas
Air Europa Logo
18:55 - 19:45BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
30h 50m1 stop Madrid Barajas
£738Air Europa
Sun, 28 Feb - Thu, 4 Mar
Turkish Airlines Logo
18:50 - 22:20PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
21h 30m1 stop Istanbul
Turkish Airlines Logo
15:15 - 20:05BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
34h 50m1 stop Istanbul
£750Turkish Airlines
Mon, 8 Mar - Wed, 10 Mar
Air Europa Logo
21:30 - 17:45PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
18:55 - 19:45BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
30h 50m1 stop Madrid Barajas
£777Air Europa
Mon, 11 Jan - Mon, 15 Feb
United Airlines Logo
16:41 - 08:05PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
33h 24m2 stops Houston George Bush Intcntl Newark
United Airlines Logo
11:15 - 19:38BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
38h 23m2 stops Newark Houston George Bush Intcntl
£808United Airlines
Mon, 18 Jan - Sun, 31 Jan
United Airlines Logo
10:00 - 13:15PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
21h 15m2 stops Newark London Heathrow
United Airlines Logo
06:45 - 20:02BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
19h 17m2 stops Munich Franz Josef Strauss Newark
£843United Airlines
Fri, 20 Nov - Thu, 3 Dec
Turkish Airlines Logo
22:00 - 17:10PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
37h 10m1 stop Istanbul
Turkish Airlines Logo
15:15 - 17:10BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
31h 55m2 stops Istanbul Bogotá El Dorado
£861Turkish Airlines
Fri, 20 Nov - Thu, 3 Dec
United Airlines Logo
10:00 - 08:55PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
40h 55m2 stops Newark Chicago O'Hare Intl
United Airlines Logo
11:15 - 14:45BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
33h 30m2 stops Newark Houston George Bush Intcntl
£880United Airlines
Mon, 11 Jan - Mon, 15 Feb
Air Europa Logo
21:30 - 17:45PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
14h 15m1 stop Madrid Barajas
Air Europa Logo
18:55 - 19:45BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
30h 50m1 stop Madrid Barajas
£920Air Europa
Mon, 1 Mar - Mon, 15 Mar
KLM Logo
22:30 - 22:20PTY  Panama City Tocumen Intl-BRU Brussels Bruxelles-National
17h 50m2 stops Paris Charles de Gaulle Amsterdam Schiphol
KLM Logo
08:05 - 16:30BRU  Brussels Bruxelles-National-PTY Panama City Tocumen Intl
14h 25m1 stop Amsterdam Schiphol
£939KLM
Booking Insights

Price, demand, and travel trends for Panama City to Brussels Bruxelles-National Airport flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights with more confidence.

How much is a return flight from Panama City to Brussels Bruxelles-National Airport?

Return flights from Panama City to Brussels Bruxelles-National Airport typically range from £661 to £863. The lowest price found in the past 5 days was £726 on Turkish Airlines.

What's the cheapest day of the week to fly from Panama City to Brussels Bruxelles-National Airport?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Panama City to Brussels Bruxelles-National Airport. It's 13% cheaper than the average day, while Tuesday is the most expensive, with prices 5% higher.

What is the cheapest month to fly from Panama City to Brussels Bruxelles-National Airport?

•February is the cheapest month to fly from Panama City to Brussels Bruxelles-National Airport at £652 return.
•April (£964) and September (£895) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 47% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Panama City to Brussels Bruxelles-National Airport flights

Low season

December

Cheapest flight

£726
Beat the crowds with an average 46% drop in traveller numbers.
The most popular month to fly with an average 92% increase in traveller numbers.
Return flight from Panama City to Brussels Bruxelles-National Airport

When to book flights from Panama City to Brussels

Are your dates flexible? Find out the best times to travel from Panama City to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Panama City to Brussels Bruxelles-National Airport flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines, and booking tips.

  • How long is a flight from Panama City to Brussels Bruxelles-National Airport?

    A direct flight from Panama City to Brussels Bruxelles-National Airport takes 00m, covering 5,462 miles.

  • Do I need a passport to fly from Panama City to Brussels Bruxelles-National Airport?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Panama City to Brussels Bruxelles-National Airport flight?

    Return flights from Panama City to Brussels Bruxelles-National Airport range from £661 to £863, with an average of £756 over the past 12 months. Anything below £661 counts as a good deal.

  • Have flight prices from Panama City to Brussels Bruxelles-National Airport changed much recently?

    Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about £726 to £1,463. That means the highest observed fare was about 2x higher than the lowest one.

  • How are flight prices from Panama City to Brussels Bruxelles-National Airport looking right now?

    One-way fares from Panama City to Brussels Bruxelles-National Airport are currently higher than usual. Average one-way flight prices are about £1,280, which is 148% above the typical average for this route.

  • Which car hire options are available at Brussels Bruxelles-National Airport (BRU)?

    Brussels Bruxelles-National Airport (BRU) hosts 5 major car hire companies, with daily rates averaging £36 for economy cars. Top options include:

    • Alamo
    • Hertz
    • keddy by Europcar
    • Europcar
    • Sixt

  • Which airports can I use when flying from Panama City to Brussels Bruxelles-National Airport?

    Flights from Panama City to Brussels Bruxelles-National Airport usually depart from Panama City Tocumen Intl (PTY) and arrive at Brussels Bruxelles-National (BRU).

  • Which airports do connecting flights from Panama City to Brussels Bruxelles-National Airport pass through?

    One-stop flights from Panama City to Brussels Bruxelles-National Airport most commonly connect through:

    • Madrid Barajas (MAD) – 58% of one-stop connections
    • Istanbul (IST) – 21% of one-stop connections
    • Amsterdam Schiphol (AMS) – 15% of one-stop connections
    • Newark (EWR) – 5% of one-stop connections

  • Can I save money by using flexible dates for flights from Panama City to Brussels Bruxelles-National Airport?

    Yes. Flexible dates can save you up to 17% on flights from Panama City to Brussels Bruxelles-National Airport. Wednesday is the cheapest departure day at £661 return on average, while Tuesday is the most expensive at £796, a difference of £135.

    KAYAK's flexible dates feature shows options up to three days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different stopover airport from Panama City to Brussels Bruxelles-National Airport?

    Flying via Amsterdam Schiphol (AMS) gives the shortest average 1-stop total travel time of 14h 49m, compared to 15h 05m via Madrid Barajas (MAD) and 15h 09m via Newark (EWR).

  • What is the time difference between Panama City and Brussels Bruxelles-National Airport?

    Brussels Bruxelles-National Airport is 6 hours ahead of Panama City (Central European Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Brussels Bruxelles-National Airport?

    Some of the most popular sights in Brussels Bruxelles-National Airport are Grand Place, Brussels City Hall, and Cirque Royal. These are among the most viewed places in Brussels Bruxelles-National Airport on KAYAK.

Your guide to booking Panama City to Brussels Bruxelles-National Airport flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Tuesday. On this route, Wednesday flights average £661, about £135 less than Tuesday fares (17% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Panama City to Brussels Bruxelles-National Airport trip for February. Fares historically average £652 return in that month – typically £312 less than the most expensive month, which is April (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Brussels Bruxelles-National Airport.

    • NH Brussels Airport
    • Crowne Plaza Brussels Airport By IHG

More options for your flight from Panama City to Brussels

Complete your trip to Brussels with a hotel stay or car hire

Car hire in Brussels
Hotels in Brussels
Holidays in Brussels