MAD - PTY

£272 Find Cheap Flights from Madrid to Panama City – Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Panama City departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest return fare
£607
Typical prices: £672-£935
Delta
Mon 17/8Mon 24/8
MAD - PTY • 2 stops
Cheapest direct flights
£611
Typical prices: £619-£1,284
Iberia
Wed 18/11Wed 2/12
MAD - PTY • Direct
Top airlines
Cheapest • from £607 (return)
Best reviews • 7.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Direct flights
You can fly direct with Air Europa and Iberia. Average duration is 10h 37m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 75% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
Top stopover airports
Cheapest • Avg £450 (return)
Shortest trip • 15h 18m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travellers who book at least 3 weeks in advance save around 11% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 15% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Madrid to Panama City (MAD-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Madrid to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Madrid to Panama City

Mon, 17 Aug - Mon, 24 Aug
Delta Logo
06:00 - 12:55
MAD
-
PTY
37h 55m
2 stops
Delta Logo
14:20 - 06:20
PTY
-
MAD
33h 00m
2 stops
£607Delta
Mon, 7 Sep - Mon, 14 Sep
Delta Logo
10:05 - 12:58
MAD
-
PTY
33h 53m
2 stops
Delta Logo
14:23 - 06:20
PTY
-
MAD
32h 57m
2 stops
£607Delta
Tue, 18 Aug - Tue, 25 Aug
Delta Logo
12:20 - 12:55
MAD
-
PTY
31h 35m
2 stops
Delta Logo
14:20 - 06:20
PTY
-
MAD
33h 00m
2 stops
£607Delta
Mon, 14 Sep - Mon, 28 Sep
Delta Logo
06:00 - 12:58
MAD
-
PTY
37h 58m
2 stops
Delta Logo
14:23 - 06:20
PTY
-
MAD
32h 57m
2 stops
£607Delta
Wed, 18 Nov - Wed, 2 Dec
Iberia Logo
12:00 - 17:05
MAD
-
PTY
11h 05mdirect
Iberia Logo
18:35 - 10:40
PTY
-
MAD
10h 05mdirect
£611Iberia
Mon, 31 Aug - Fri, 18 Sep
Air Europa Logo
15:05 - 18:40
MAD
-
PTY
10h 35mdirect
Air Europa Logo
20:25 - 13:15
PTY
-
MAD
9h 50mdirect
£612Air Europa
Wed, 2 Sep - Sun, 20 Sep
Air Europa Logo
15:05 - 18:40
MAD
-
PTY
10h 35mdirect
Air Europa Logo
20:25 - 13:15
PTY
-
MAD
9h 50mdirect
£612Air Europa
Wed, 16 Sep - Sun, 11 Oct
Air Europa Logo
15:05 - 18:40
MAD
-
PTY
10h 35mdirect
Air Europa Logo
20:25 - 13:15
PTY
-
MAD
9h 50mdirect
£612Air Europa
Wed, 9 Sep - Sat, 26 Sep
Iberia Logo
15:55 - 19:35
MAD
-
PTY
10h 40mdirect
Iberia Logo
13:16 - 12:50
PTY
-
MAD
16h 34m
1 stop
£680Iberia
Fri, 11 Sep - Sun, 27 Sep
Iberia Logo
15:55 - 19:35
MAD
-
PTY
10h 40mdirect
Iberia Logo
13:16 - 09:55
PTY
-
MAD
13h 39m
1 stop
£680Iberia
Booking Insights

KAYAK’s insights & trends for Madrid to Panama City flights

Get data-powered insights and trends into flights from Madrid to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a return flight from Madrid to Panama City?

This analysis is based on the cheapest return trip price found on KAYAK in the last 12 months by searching for a flight from Madrid to Panama City departing in September.

Flight prices are below average for this route right now.

Flights to Panama City from Madrid usually cost between £672 and £935 in September.
The lowest price found in the past 5 days was £607 on Delta (14 Sept–28 Sept).

What’s the cheapest day of the week to fly from Madrid to Panama City?

The average price of all round-trip flights from Madrid to Panama City clicked on KAYAK for each day over the last 12 months.

For Madrid to Panama City, Wednesday is the cheapest day to fly on average and Monday is the most expensive. Flying from Panama City back to Madrid, the best deals are generally found on Wednesday, with Tuesday being the most expensive.

What is the cheapest month to fly from Madrid to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Panama City is April, where tickets cost £549 (return) on average. On the other hand, the most expensive months are December and August, where the average cost of round-trip tickets is £828 and £789 respectively.

Can I save money by flying with a stopover from Madrid to Panama City?

The average return price for all direct flights, flights with one stopover, and flights with two stopovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a stopover may cost you more time, but you can also save money on the route, with a 1 stop stopover the cheapest option at £572 on average.

How far in advance should I book a flight from Madrid to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Panama City, you should book around 3 weeks before departure, which saves you about 11% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Panama City

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Good to know - Cheap tickets from Madrid to Panama City

Low season

May

Cheapest flight

£272
Best time to beat the crowds (13% less expensive on average)
Most popular time to fly (12% more expensive on average)
Flight from Madrid to Panama City

When to book flights from Madrid to Panama City

Are your dates flexible? Find out the best times to travel from Madrid to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Panama City

  • What is the cheapest flight from Madrid to Panama City?

    In the last 5 days, the lowest price for a flight from Madrid to Panama City was £272 for a one-way ticket and £607 for a return.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Panama City?

    Iberia, and Copa Airlines offer inflight Wi-Fi service on the Madrid to Panama City flight route.

  • Which aircraft models fly most regularly from Madrid to Panama City?

    The Boeing 787-9 Dreamliner is the aircraft model that flies most regularly on the Madrid to Panama City flight route.

  • Which airline alliances offer flights from Madrid to Panama City?

    oneworld, and SkyTeam are the airline alliances operating flights between Madrid and Panama City, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Panama City?

    There are direct flights from Madrid to Panama City on a daily basis.

  • Which is the best airline for flights from Madrid to Panama City, Air Europa or Iberia?

    The two airlines most popular with KAYAK users for flights from Madrid to Panama City are Air Europa and Iberia. With an average price for the route of £571 and an overall rating of 7.0, Air Europa is the most popular choice. Iberia is also a great choice for the route, with an average price of £532 and an overall rating of 7.0.

  • How does KAYAK find such low prices on flights from Madrid to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Panama City with an airline and back to Madrid with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Panama City

  • Looking for a cheap flight from Panama City to Madrid? 25% of our users found flights on this route for £606 or less round-trip.

Prefer to fly direct from Madrid to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Panama City Tocumen Intl.
Find which airlines fly direct from Madrid Barajas Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa,Iberia

Air Europa,Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa,Iberia

Air Europa,Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa,Iberia

Air Europa,Iberia

Saturday

Air Europa

Air Europa

Sunday

Air Europa,Iberia

Air Europa,Iberia

See more direct flights

Direct returns

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa,Iberia

Air Europa,Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa,Iberia

Air Europa,Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa,Iberia

Air Europa,Iberia

Saturday

Air Europa

Air Europa

Sunday

Air Europa,Iberia

Air Europa,Iberia

See more direct flights

Reviews of the top airlines flying from Madrid to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
Air EuropaOverall score based on 629 reviews
7.5Crew
6.9Comfort
6.5Entertainment
7.1Boarding
6.3Food
Airline reviews

There are often trade-offs involved with flying cheaper airlines. With Air Europa, their crowd control is terrible--the line at check-in in Madrid was absolutely hideous 3 hours before departure. These 787 "Dreamliners" are cheaply-made and uncomfortable. And disembarking at JFK was horrid...it was 11 p.m., yet we were force to deal with those off-site shuttle buses, presumably because Air Europa doesn't want to pay what it costs for an actual gate. But as usual, the worst aspect of Air Europa flights are tones fellow passengers: unruly and oblivious to such concepts as personal space. The crew was, on the other hand, lovely.

4.0 OkayAnonymous, Jun 2026
MAD - JFK
Read more Air Europa reviews

There are often trade-offs involved with flying cheaper airlines. With Air Europa, their crowd control is terrible--the line at check-in in Madrid was absolutely hideous 3 hours before departure. These 787 "Dreamliners" are cheaply-made and uncomfortable. And disembarking at JFK was horrid...it was 11 p.m., yet we were force to deal with those off-site shuttle buses, presumably because Air Europa doesn't want to pay what it costs for an actual gate. But as usual, the worst aspect of Air Europa flights are tones fellow passengers: unruly and oblivious to such concepts as personal space. The crew was, on the other hand, lovely.

The flight was long but everything went well. Crew was helpful and very attentive. Food was good and the entertainment options were many.

My long-haul flight experience with this airline was not very pleasant. Earphones were paid, and no eye mask or other amenities were provided. The meals were served in cardboard boxes with plastic cutlery. The restroom was unclean and ran out of toilet paper. However, the boarding process was smooth and well organized.

We experienced a delay of almost two hours before takeoff. For a flight of more than 10 hours, sitting on the runway for two hours is quite exhausting. The airline did nothing to attend to the passengers during that time. We were not given any courtesy drinks or snacks—only the bare minimum during the flight. The crew seemed very apologetic, but apparently they have restrictions imposed by the airline, because despite their friendliness, they provided strictly what was necessary and, of course, everything else was for sale. However, after a two-hour delay, one would expect at least complimentary beverages. In addition to this, the space between the rows of seats is inhumanely narrow. Air Europa should review this for such long flights and be a bit more considerate and humane with its customers.

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

Very cheap airline, not worth the price. And they almost lost my luggage at JFK during a direct flight. I can't believe I paid that much money for a horrible 'premium economy' flight. Just fly economy on the cheapest end; premium economy is no different. Very very poor.

All four segments of my trip on Iberia were late for various reasons. No apparent effort to stay on schedule. Never flying Iberia again.

The flight from Madrid to Boston was awful. Without prior warning, I was seated in the row in front of an exit row where my seat did not recline. The person in front of me reclined, reducing my already tiny space further. This was the WORST flight I've ever had.

Overall it was okay. Just the lost baggage and how they are handling it

Puddle-hopper. Quick-ish flight. Don’t expect to have much/any in-flight entertainment (movies/TV, etc).

Worst flight I ever experienced, what was supposed to a 7 hour flight ended being 13 hours on a plane with no ac and the worst cabin I have ever seen. Never again.

Horrible seat at the back. Crew was very kind. Packed plane. Wordy pilot bragging about Iberia being punctual when many of us came from Alicante flight that was delayed an hour and many lost connection and we lost our luggage. Still waiting for it

Excellent plane, 787. Very good seat and additional stuff they provide. Good food. Very good staff.

Excellent except WiFi is a Must on Biz class 10 hour flight ! Didn’t work entire flight. SW doesn’t do that.

Worst flight in years.. is not easy to flight 11 hours without entertainment onboard and the crew was not empathetic about it or even gave an apology for the inconvenience. Poor treatment to the passengers, and some responses where roughly given.

Everything you need to know for your flight from Madrid to Panama City

Information on your arrival and departure airports