£304 Find Cheap Flights from Madrid to Panama City – Compare and Save

Among airlines operating Madrid to Panama City flights:

• Air Europa: offers extra legroom; offers free seat selection
• Iberia: offers free seat selection
• Copa Airlines: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

2 airlines operate flights between Madrid and Panama City. The airlines offering direct flights on this route include:

• Air Europa
• Iberia

Flights from Madrid to Panama City usually depart from Madrid Barajas (MAD) and arrive at Panama City Tocumen Intl (PTY).

Here are some options for this route, based on selected ticket types and cabin classes:

• Air Europa: a cabin bag and a checked bag in Economy class
• Iberia: a cabin bag and a checked bag in Economy class
• Copa Airlines: a cabin bag and a checked bag in Economy class

Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.

Two cabin classes are available on flights from Madrid to Panama City:

• Economy class
• Business Class

On this route, stopover flights are cheaper than direct options on average. Stopover fares average £566 return via Atlanta Hartsfield-Jackson (ATL), compared with £643 for direct.

There is no standard. Checked bag policies vary by airline on this route. Most carriers charge £49–£74 for the first checked bag in Economy. Premium fares and elite status bookings typically include a free checked bag.

The Boeing 787-9 Dreamliner family is used most often on this route, operated mainly by Air Europa. Other aircraft seen on the route include Airbus A330-200 variants.

One-stop flights from Madrid to Panama City most commonly connect through:

• Bogotá El Dorado (BOG) – 67% of one-stop connections
• Paris Charles de Gaulle (CDG) – 8% of one-stop connections
• Istanbul (IST) – 7% of one-stop connections
• Newark (EWR) – 5% of one-stop connections

Bogotá El Dorado (BOG) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 16% on the Madrid to Panama City route. Thursday is the cheapest departure day at £613 return on average, while Saturday is the most expensive at £724, a difference of £111. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Madrid to Panama City route, 26% of flights were delayed in the past 3 months, with delays averaging 2 hours 24 minutes.

Afternoon is the busiest departure period on Madrid to Panama City flights, with 100% leaving in that window. Morning departures account for 0%, Evening flights for 0%, and Night flights for 0%.

Multicentro Panama is one of the most viewed places in Panama City on KAYAK.

These are the earliest and latest flight times available from Madrid to Panama City:

• Earliest: departs at 12:00 and lands at 22:41
• Latest: departs at 15:55 and lands at 02:36.

The flight takes about 10h 41m.

Last-minute fares on this route (booked within 2 weeks of departure) run 15% above the route average of £663. Book 17 weeks before departure for the lowest fares.

A direct flight from Madrid to Panama City takes 10h 41m, covering 5,065 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about £500 to £4,408. That means the highest observed fare was about 9x higher than the lowest one.

One-way fares from Madrid to Panama City are currently lower than usual. Average one-way flight prices are about £387, which is 10% below the typical average for this route.

Evening flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time of 14h 27m, compared to 15h 24m via Paris Charles de Gaulle (CDG) and 16h 00m via San José Juan Santamaria Intl (SJO).

Panama City is 7 hours behind Madrid (Eastern Time vs Central European Time). Plan for the time shift when scheduling connections or first-day activities.

Panama City Tocumen Intl Airport (PTY) hosts 5 major car hire companies, with daily rates starting from around £1 for economy cars. Top options include:
· Avis
· Europcar
· Ace
· Budget
· Hertz

Return flights from Madrid to Panama City range from £558 to £826, with an average of £663 over the past 12 months. Anything below £558 counts as a good deal.

Two airlines offer in-flight Wi-Fi on Madrid to Panama City flights:

• • Iberia
• • Copa Airlines