PTY - MAD

£444 Find Cheap Flights from Panama City to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid, as well as popular online travel agencies
Travellers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest return fare
£540
Typical prices: £537-£672
Turkish Airlines
Mon 13/4Mon 20/4
PTY - MAD • 1 stop
Cheapest direct flights
£550
Typical prices: £516-£650
Air Europa
Tue 28/4Sat 16/5
PTY - MAD • Direct
Advice from real travellers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Iberia’s Wi-Fi offers free messaging for members.
Air Europa’s Business Class includes lounge access.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Cheapest • from £540 (return)
Best reviews • 6.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Direct flights
You can fly direct with Air Europa and Iberia. Average duration is 9h 57m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 89% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travellers who book at least 7 weeks in advance save around 19% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 11% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches hundreds of sites at once to find you the best travel deals.
We hope you love your trip to Madrid!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Madrid (PTY-MAD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Panama City to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Panama City to Madrid

Mon, 13 Apr - Mon, 20 Apr
Turkish Airlines Logo
22:20 - 22:35
PTY
-
MAD
41h 15m
1 stop
Turkish Airlines Logo
07:40 - 20:25
MAD
-
PTY
19h 45m
1 stop
£540Turkish Airlines
Wed, 27 May - Wed, 3 Jun
Turkish Airlines Logo
22:20 - 10:25
PTY
-
MAD
29h 05m
1 stop
Turkish Airlines Logo
18:25 - 18:30
MAD
-
PTY
31h 05m
2 stops
£541Turkish Airlines
Mon, 20 Apr - Tue, 28 Apr
Turkish Airlines Logo
22:20 - 16:55
PTY
-
MAD
35h 35m
1 stop
Turkish Airlines Logo
12:00 - 20:25
MAD
-
PTY
39h 25m
1 stop
£545Turkish Airlines
Tue, 28 Apr - Sat, 16 May
Air Europa Logo
20:25 - 13:15
PTY
-
MAD
9h 50mdirect
Air Europa Logo
15:05 - 18:40
MAD
-
PTY
10h 35mdirect
£550Air Europa
Wed, 15 Apr - Wed, 22 Apr
Turkish Airlines Logo
22:20 - 10:25
PTY
-
MAD
29h 05m
1 stop
Turkish Airlines Logo
07:40 - 20:25
MAD
-
PTY
19h 45m
1 stop
£552Turkish Airlines
Sun, 19 Apr - Thu, 23 Apr
Air Europa Logo
20:25 - 13:15
PTY
-
MAD
9h 50mdirect
Air Europa Logo
15:05 - 18:40
MAD
-
PTY
10h 35mdirect
£553Air Europa
Sat, 25 Apr - Sat, 2 May
Multiple Airlines Logo
14:27 - 12:15
PTY
-
MAD
14h 48m
1 stop
Multiple Airlines Logo
20:30 - 16:50
MAD
-
PTY
27h 20m
1 stop
£555Multiple Airlines
Mon, 20 Apr - Wed, 20 May
Turkish Airlines Logo
22:20 - 16:55
PTY
-
MAD
35h 35m
1 stop
Turkish Airlines Logo
07:40 - 20:25
MAD
-
PTY
19h 45m
1 stop
£556Turkish Airlines
Mon, 20 Apr - Wed, 10 Jun
Turkish Airlines Logo
22:20 - 10:25
PTY
-
MAD
29h 05m
1 stop
Turkish Airlines Logo
07:40 - 20:25
MAD
-
PTY
19h 45m
1 stop
£556Turkish Airlines
Wed, 27 May - Wed, 3 Jun
Turkish Airlines Logo
22:20 - 10:25
PTY
-
MAD
29h 05m
1 stop
Turkish Airlines Logo
07:40 - 20:25
MAD
-
PTY
19h 45m
1 stop
£559Turkish Airlines
Booking Insights

KAYAK’s insights & trends for Panama City to Madrid flights

Get data-powered insights and trends into flights from Panama City to Madrid to help you find the cheapest flights, the best time to fly and much more.

How much is a return flight from Panama City to Madrid?

This analysis is based on the cheapest return trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to Madrid departing in May.

What’s the cheapest day of the week to fly from Panama City to Madrid?

The average price of all round-trip flights from Panama City to Madrid clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to Madrid, look for departures on Wednesdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Madrid, Wednesday is the cheapest day to fly and Monday is the most expensive.

What is the cheapest month to fly from Panama City to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Madrid is February, where tickets cost £548 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is £711 and £692 respectively.

Can I save money by flying with a stopover from Panama City to Madrid?

The average return price for all direct flights, flights with one stopover, and flights with two stopovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a stopover may cost you more time, but you can also save money on the route, with a 1 stop stopover the cheapest option at £600 on average.

How far in advance should I book a flight from Panama City to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Madrid, you should book around 7 weeks before departure, which saves you about 19% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Madrid

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Good to know - Cheap tickets from Panama City to Madrid

Low seasonJanuary
Cheapest flight£444
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly (1% more expensive on average)
Flight from Panama City to Madrid

When to book flights from Panama City to Madrid

Are your dates flexible? Find out the best times to travel from Panama City to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Madrid

  • What is the cheapest flight from Panama City to Madrid?

    In the last 3 days, the lowest price for a flight from Panama City to Madrid was £444 for a one-way ticket and £540 for a return.

  • Which airports will I be using when flying from Panama City to Madrid?

    On your way to Madrid, you’ll fly out from Panama City Tocumen Intl. You’ll be landing at Madrid Barajas.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Madrid?

    All the following airlines offer inflight Wi-Fi service on the Panama City to Madrid flight route: Iberia, Copa Airlines, Air France, British Airways, Finnair, and Air Europa.

  • Which aircraft models fly most regularly from Panama City to Madrid?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Panama City to Madrid flight route.

  • Which airline alliances offer flights from Panama City to Madrid?

    SkyTeam is the only airline alliance operating flights between Panama City and Madrid.

  • On which days can I fly direct from Panama City to Madrid?

    There are direct flights from Panama City to Madrid on a daily basis.

  • How does KAYAK find such low prices on flights from Panama City to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Madrid with an airline and back to Panama City with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Madrid

  • Looking for a cheap flight from Madrid to Panama City? 25% of our users found flights on this route for £545 or less round-trip.

Prefer to fly direct from Panama City to Madrid?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Madrid Barajas.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa

Air Europa

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa,Iberia

Air Europa,Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa,Iberia

Air Europa,Iberia

Saturday

Air Europa

Air Europa

Sunday

Air Europa,Iberia

Air Europa,Iberia

See more direct flights

Direct returns

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa

Air Europa

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa,Iberia

Air Europa,Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa,Iberia

Air Europa,Iberia

Saturday

Air Europa

Air Europa

Sunday

Air Europa,Iberia

Air Europa,Iberia

See more direct flights

Reviews of the top airline flying from Panama City to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
6.9
Air EuropaOverall score based on 593 reviews
6.2Food
7.1Boarding
6.5Entertainment
6.8Comfort
7.4Crew
Airline reviews

My long-haul flight experience with this airline was not very pleasant. Earphones were paid, and no eye mask or other amenities were provided. The meals were served in cardboard boxes with plastic cutlery. The restroom was unclean and ran out of toilet paper. However, the boarding process was smooth and well organized.

4.0 OkayAnonymous, Feb 2026
VCE - MAD
Read more Air Europa reviews

My long-haul flight experience with this airline was not very pleasant. Earphones were paid, and no eye mask or other amenities were provided. The meals were served in cardboard boxes with plastic cutlery. The restroom was unclean and ran out of toilet paper. However, the boarding process was smooth and well organized.

We experienced a delay of almost two hours before takeoff. For a flight of more than 10 hours, sitting on the runway for two hours is quite exhausting. The airline did nothing to attend to the passengers during that time. We were not given any courtesy drinks or snacks—only the bare minimum during the flight. The crew seemed very apologetic, but apparently they have restrictions imposed by the airline, because despite their friendliness, they provided strictly what was necessary and, of course, everything else was for sale. However, after a two-hour delay, one would expect at least complimentary beverages. In addition to this, the space between the rows of seats is inhumanely narrow. Air Europa should review this for such long flights and be a bit more considerate and humane with its customers.

I flew in business a couple of months ago, it was great, tried again in economy, it is the cramped seat I have ever been into, for an overseas flight across the atlantic it is inhumane to put passengers in such cramped space. Other than that, everything ok. Took a second flight from Madrid to London, also economy and it was roomy and perfect.

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

Everything you need to know for your flight from Panama City to Madrid

Information on your arrival and departure airports