PTY - MAD

£377 Find Cheap Flights from Panama City to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid, as well as popular online travel agencies
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Flight Deals
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Booking Insights
Flight Deals

Cheap Flights from Panama City to Madrid (PTY-MAD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Panama City to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Panama City to Madrid

Tue, 14 Oct - Fri, 31 Oct
Air Europa Logo
20:25 - 13:15PTY-MAD
9h 50mdirect
Air Europa Logo
15:10 - 19:45MAD-PTY
10h 35mdirect
£508Air Europa
Find Deal
Thu, 13 Nov - Mon, 24 Nov
Air Europa Logo
21:30 - 13:05PTY-MAD
9h 35mdirect
Air Europa Logo
15:10 - 19:45MAD-PTY
10h 35mdirect
£509Air Europa
Find Deal
Tue, 14 Oct - Fri, 31 Oct
Air Europa Logo
20:25 - 13:15PTY-MAD
9h 50mdirect
Air Europa Logo
15:10 - 19:45MAD-PTY
10h 35mdirect
£509Air Europa
Find Deal
Tue, 21 Oct - Thu, 6 Nov
KLM Logo
18:50 - 19:30PTY-MAD
17h 40m1 stop
KLM Logo
06:00 - 16:30MAD-PTY
16h 30m1 stop
£529KLM
Find Deal
Wed, 29 Oct - Sun, 9 Nov
Turkish Airlines Logo
21:45 - 10:25PTY-MAD
30h 40m1 stop
Turkish Airlines Logo
17:55 - 19:50MAD-PTY
31h 55m1 stop
£531Turkish Airlines
Find Deal
Tue, 21 Oct - Mon, 27 Oct
 Logo
18:50 - 16:25PTY-MAD
14h 35m1 stop
 Logo
20:05 - 20:10MAD-PTY
30h 05m1 stop
Fri, 3 Oct - Tue, 21 Oct
Turkish Airlines Logo
21:55 - 16:50PTY-MAD
35h 55m1 stop
Turkish Airlines Logo
12:00 - 20:00MAD-PTY
39h 00m1 stop
£548Turkish Airlines
Find Deal
Sat, 25 Oct - Sat, 1 Nov
Iberia Logo
17:10 - 10:15PTY-MAD
10h 05mdirect
Iberia Logo
11:40 - 16:45MAD-PTY
11h 05mdirect
£560Iberia
Find Deal
Thu, 6 Nov - Thu, 13 Nov
 Logo
18:45 - 16:05PTY-MAD
15h 20m1 stop
 Logo
18:45 - 20:10MAD-PTY
31h 25m1 stop
Thu, 25 Dec - Tue, 6 Jan
KLM Logo
18:45 - 13:40PTY-MAD
36h 55m1 stop
KLM Logo
20:30 - 19:55MAD-PTY
29h 25m1 stop
£592KLM
Find Deal

Everything you should know

Our travellers' advice
AI-generated summary based on content written by travel experts
Iberia’s Wi-Fi offers free messaging for members.
Air Europa’s Business Class includes lounge access.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Air Europa
Cheapest • from £508 (return)
Air Europa
Best reviews • 7.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
7 weeks
in advance
Our data shows that travellers who book at least 7 weeks in advance save around 17% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 11% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest return fare
£508
Typical prices: £501-609
Air Europa
Tue 14/10Fri 31/10
PTY - MAD • Direct
Cheapest one-way flight
£377
Typical prices: £294-430
KLM
Tue 11/11
PTY - MAD • 1 stop
Start a new search
KAYAK searches hundreds of sites at once to find you the best travel deals.
We hope you love your trip to Madrid!
Expert advice

Expert advice for your flight from Panama City to Madrid

 
Snippets provided in this section are AI-generated based on a summarisation of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Iberia

Iberia’s business class offers all-aisle access and private suites on A350-900s for restful flights.


Iberia’s Wi-Fi offers global coverage with free messaging for Iberia Plus members on all flights.

Read more about Iberiaby Marisa Garcia
Air Europa

Air Europa’s Business Class includes Wi-Fi and VIP lounge access, ideal for working travelers.


Air Europa’s SUMA Gold offers lounge access and priority baggage collection for frequent flyers.

Our travel experts
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Read more
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Booking Insights

KAYAK's insights & trends for Panama City to Madrid flights

Get data-powered insights and trends into flights from Panama City to Madrid to help you find the cheapest flights, the best time to fly and much more.

How much is a return flight from Panama City to Madrid?

What’s the cheapest day of the week to fly from Panama City to Madrid?

The average price of all round-trip flights from Panama City to Madrid clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to Madrid, look for departures on Tuesdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Madrid, Saturday is the cheapest day to fly and Wednesday is the most expensive.

What is the cheapest month to fly from Panama City to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Madrid is March, where tickets cost £511 (return) on average. On the other hand, the most expensive months are July and August, where the average cost of round-trip tickets is £648 and £646 respectively.

How far in advance should I book a flight from Panama City to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Madrid, you should book around 7 weeks before departure, which saves you about 17% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 12 weeks before departure.

Good to know - Cheap tickets from Panama City to Madrid

Low seasonJuly
Cheapest flight£377
Best time to beat the crowds but there is an average 13% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Panama City to Madrid

When to book flights from Panama City to Madrid

Are your dates flexible? Find out the best times to travel from Panama City to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Madrid

  • What is the cheapest flight from Panama City to Madrid?

    In the last 3 days, the lowest price for a flight from Panama City to Madrid was £510 for a one-way ticket and £688 for a return.

  • Which airports will I be using when flying from Panama City to Madrid?

    On your way to Madrid, you’ll fly out from Panama City Tocumen Intl. You’ll be landing at Madrid Barajas.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Madrid?

    Iberia, Copa Airlines, Air France, British Airways, and Finnair offer inflight Wi-Fi service on the Panama City to Madrid flight route.

  • Which aircraft models fly most regularly from Panama City to Madrid?

    The Boeing 787-9 Dreamliner is the aircraft model that flies most regularly on the Panama City to Madrid flight route.

  • Which airline alliances offer flights from Panama City to Madrid?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Panama City and Madrid, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Madrid?

    There are direct flights from Panama City to Madrid on a daily basis.

  • How does KAYAK find such low prices on flights from Panama City to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Madrid with an airline and back to Panama City with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Madrid

  • Looking for a cheap flight from Madrid to Panama City? 25% of our users found flights on this route for £660 or less round-trip.

Prefer to fly direct from Panama City to Madrid?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Madrid Barajas.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa, Iberia

Air Europa, Iberia

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa, Iberia

Air Europa, Iberia

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa

Air Europa

See more direct flights

Direct returns

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa, Iberia

Air Europa, Iberia

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa, Iberia

Air Europa, Iberia

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa

Air Europa

See more direct flights

Reviews of the top airline flying from Panama City to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
Air EuropaOverall score based on 556 reviews
7.1Boarding
6.6Entertainment
7.0Comfort
6.3Food
7.5Crew
Airline reviews

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

8.0 ExcellentJustin, Sept 2025MAD - AGP
Read more Air Europa reviews

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

The plane was very old, no power outlets. We also had to wait a long time to board. They kept moving us to different lines before we actually could step foot on the plane. We ended up being delayed an hour but we were never told or informed for any reason. After the meal I asked for a coffee which the flight attendant forgot and I had to ask again. Overall not the worst but not the best experience.

Need to pay for headsets, water, or any extra except air to breath.

Sitting space was very tight and I am not big or fat (I am 5'10" 178 Lb), so eating was very challenging. The rest was good.

Sitting space was very tight, so eating was difficult. But everything else was good.

12 hours flight. Only one meal, not enough food. At the galley only water during the flight. Lavatories not clean. Headsets at extra cost.

Need to pay for a cup of water. No food. Need to pay for headsets.

Everything should improve! Service like a low cost but prices like a premium airline. Crew in general with bad manners arguing for everything. You pay for priority access but then they use buses, so your loose your advantage to put your carry on first. That was the purpose for paying for priority. Bording is a nightmare, people accessing the plane for bothering doors, front and rear, no matter which line do you have.

Everything you need to know for your flight from Panama City to Madrid

Information on your arrival and departure airports

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