PTY - MAD

£454 Find Cheap Flights from Panama City to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 28/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid, as well as popular online travel agencies
Travellers love KAYAK
41.299.237 searches in the past 7 days on KAYAK

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Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest return fare
£481
Overall average: £520
Iberia
Sun 10/5Fri 22/5
PTY - MAD • Direct
Cheapest one-way flight
£454
Typical prices: £339-£491
Air Europa
Sun 28/6
PTY - MAD • Direct
Our travellers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Iberia’s Wi-Fi offers free messaging for members.
Air Europa’s Business Class includes lounge access.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Iberia
Cheapest • from £481 (return)
Air Europa
Best reviews • 6.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
6 weeks
in advance
Our data shows that travellers who book at least 6 weeks in advance save around 17% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
February
Cheapest • 9% price drop
May
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches hundreds of sites at once to find you the best travel deals.
We hope you love your trip to Madrid!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Madrid (PTY-MAD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Panama City to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Panama City to Madrid

Sun, 10 May - Fri, 22 May
Iberia Logo
21:30 - 14:20
PTY
-
MAD
9h 50mdirect
Iberia Logo
15:55 - 20:00
MAD
-
PTY
11h 05mdirect
£481Iberia
Mon, 1 Jun - Wed, 10 Jun
Multiple Airlines Logo
18:50 - 09:30
PTY
-
MAD
31h 40m
1 stop
Multiple Airlines Logo
16:40 - 19:45
MAD
-
PTY
34h 05m
1 stop
£484Multiple Airlines
Fri, 1 May - Sun, 31 May
Iberia Logo
21:30 - 14:20
PTY
-
MAD
9h 50mdirect
Iberia Logo
15:55 - 20:00
MAD
-
PTY
11h 05mdirect
£489Iberia
Mon, 15 Jun - Mon, 22 Jun
Multiple Airlines Logo
18:50 - 16:25
PTY
-
MAD
14h 35m
1 stop
Multiple Airlines Logo
12:20 - 19:45
MAD
-
PTY
14h 25m
1 stop
£491Multiple Airlines
Mon, 25 May - Mon, 15 Jun
Multiple Airlines Logo
18:50 - 09:30
PTY
-
MAD
31h 40m
1 stop
Multiple Airlines Logo
12:20 - 19:45
MAD
-
PTY
14h 25m
1 stop
£498Multiple Airlines
Mon, 9 Feb - Mon, 23 Feb
KLM Logo
18:45 - 10:15
PTY
-
MAD
33h 30m
1 stop
KLM Logo
20:30 - 16:30
MAD
-
PTY
26h 00m
1 stop
£500KLM
Mon, 8 Jun - Fri, 12 Jun
Multiple Airlines Logo
18:50 - 23:25
PTY
-
MAD
21h 35m
1 stop
Multiple Airlines Logo
12:20 - 19:45
MAD
-
PTY
14h 25m
1 stop
£502Multiple Airlines
Mon, 9 Feb - Mon, 23 Feb
KLM Logo
22:05 - 10:15
PTY
-
MAD
30h 10m
1 stop
KLM Logo
16:50 - 16:30
MAD
-
PTY
29h 40m
1 stop
£505KLM
Mon, 25 May - Sat, 13 Jun
Multiple Airlines Logo
18:50 - 09:30
PTY
-
MAD
31h 40m
1 stop
Multiple Airlines Logo
20:15 - 19:45
MAD
-
PTY
30h 30m
1 stop
£507Multiple Airlines
Wed, 27 May - Wed, 17 Jun
Iberia Logo
21:30 - 14:20
PTY
-
MAD
9h 50mdirect
Iberia Logo
15:55 - 19:35
MAD
-
PTY
10h 40mdirect
£508Iberia
Booking Insights

KAYAK's insights & trends for Panama City to Madrid flights

Get data-powered insights and trends into flights from Panama City to Madrid to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Madrid?

The average price of all round-trip flights from Panama City to Madrid clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to Madrid, look for departures on Wednesdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Madrid, Sunday is the cheapest day to fly and Monday is the most expensive.

What is the cheapest month to fly from Panama City to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Madrid is February, where tickets cost £520 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is £682 and £643 respectively.

Can I save money by flying with a stopover from Panama City to Madrid?

The average return price for all direct flights, flights with one stopover, and flights with two stopovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a stopover may cost you more time, but you can also save money on the route, with a 1 stop stopover the cheapest option at £512 on average.

How far in advance should I book a flight from Panama City to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Madrid, you should book around 6 weeks before departure, which saves you about 17% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Madrid

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Good to know - Cheap tickets from Panama City to Madrid

Low seasonJuly
Cheapest flight£454
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Panama City to Madrid

When to book flights from Panama City to Madrid

Are your dates flexible? Find out the best times to travel from Panama City to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Madrid

  • What is the cheapest flight from Panama City to Madrid?

    In the last 3 days, the lowest price for a flight from Panama City to Madrid was £454 for a one-way ticket and £481 for a return.

  • Which airports will I be using when flying from Panama City to Madrid?

    On your way to Madrid, you’ll fly out from Panama City Tocumen Intl. You’ll be landing at Madrid Barajas.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Madrid?

    All the following airlines offer inflight Wi-Fi service on the Panama City to Madrid flight route: Iberia, Copa Airlines, Air France, Air Europa, British Airways, and Finnair.

  • Which aircraft models fly most regularly from Panama City to Madrid?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Panama City to Madrid flight route.

  • Which airline alliances offer flights from Panama City to Madrid?

    SkyTeam is the only airline alliance operating flights between Panama City and Madrid.

  • On which days can I fly direct from Panama City to Madrid?

    There are direct flights from Panama City to Madrid on a daily basis.

  • How does KAYAK find such low prices on flights from Panama City to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Madrid with an airline and back to Panama City with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Madrid

  • Looking for a cheap flight from Madrid to Panama City? 25% of our users found flights on this route for £625 or less round-trip.

Prefer to fly direct from Panama City to Madrid?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Madrid Barajas.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa, Iberia

Air Europa, Iberia

See more direct flights

Direct returns

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa, Iberia

Air Europa, Iberia

See more direct flights

Reviews of the top airline flying from Panama City to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
6.9
Air EuropaOverall score based on 587 reviews
6.2Food
7.4Crew
6.5Entertainment
7.0Boarding
6.9Comfort
Airline reviews

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

2.0 MediocreAnonymous, Jan 2026
MAD - JFK
Read more Air Europa reviews

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

The plane was very old, no power outlets. We also had to wait a long time to board. They kept moving us to different lines before we actually could step foot on the plane. We ended up being delayed an hour but we were never told or informed for any reason. After the meal I asked for a coffee which the flight attendant forgot and I had to ask again. Overall not the worst but not the best experience.

Everything you need to know for your flight from Panama City to Madrid

Information on your arrival and departure airports