MEX - PTY

£137 Find Cheap Flights from Mexico City to Panama City – Compare and Save

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Everything you should know

Cheapest return flight
£273
Typical prices: £260-£382
Avianca
Mon 31/12Wed 31/1
MEX - PTY • 1 stop
Cheapest direct flights
£285
Typical prices: £266-£388
Copa Airlines
Tue 25/12Sun 30/12
MEX - PTY • Direct
Direct flights
You can fly direct with Copa Airlines and Aeromexico. Average duration is 3h 48m
Direct flights
+1
Direct flights
+1
Avoid delays
Most punctual • 96% on-time
Best time • Fewest delays
Insights
Insights
When to book
in advance
Our data shows that travellers who book at least 6 weeks in advance save around 27% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 9% price drop
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Cheapest • Avg £294 (return)
Shortest trip • 6h 59m (one-way)
Insights
Insights
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We hope you enjoy your trip to Panama City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Mexico City to Panama City (MEX-PTY)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Mexico City to Panama City

Thu, 31 Dec - Sun, 31 Jan
Avianca Logo
00:30 - 15:15MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
13h 45m1 stop Bogotá El Dorado
Avianca Logo
16:10 - 03:10PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
12h 00m1 stop Bogotá El Dorado
£273Avianca
Sun, 18 Oct - Sun, 1 Nov
Avianca Logo
00:40 - 17:00MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
15h 20m1 stop Bogotá El Dorado
Avianca Logo
18:10 - 05:15PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
12h 05m1 stop Bogotá El Dorado
£280Avianca
Fri, 25 Dec - Wed, 30 Dec
Copa Airlines Logo
15:30 - 20:20MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 50mdirect
Copa Airlines Logo
11:44 - 14:30PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 46mdirect
£285Copa Airlines
Mon, 30 Nov - Fri, 29 Jan
Copa Airlines Logo
03:25 - 08:11MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 46mdirect
Copa Airlines Logo
16:25 - 19:20PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 55mdirect
£295Copa Airlines
Thu, 12 Nov - Thu, 26 Nov
Copa Airlines Logo
13:10 - 17:59MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 49mdirect
Copa Airlines Logo
19:18 - 22:25PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
4h 07mdirect
£303Copa Airlines
Tue, 26 Jan - Fri, 26 Mar
Copa Airlines Logo
05:55 - 10:38MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 43mdirect
Copa Airlines Logo
16:16 - 19:20PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
4h 04mdirect
£305Copa Airlines
Thu, 8 Oct - Mon, 19 Oct
Copa Airlines Logo
15:30 - 20:14MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 44mdirect
Copa Airlines Logo
16:12 - 19:05PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 53mdirect
£314Copa Airlines
Fri, 13 Nov - Mon, 16 Nov
Copa Airlines Logo
13:10 - 17:59MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 49mdirect
Copa Airlines Logo
09:24 - 12:10PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 46mdirect
£322Copa Airlines
Wed, 7 Oct - Sat, 17 Oct
Copa Airlines Logo
02:10 - 06:51MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
3h 41mdirect
Copa Airlines Logo
21:28 - 00:15PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
3h 47mdirect
£325Copa Airlines
Fri, 1 Jan - Sat, 30 Jan
Avianca Logo
05:00 - 17:15MEX  Mexico City Benito Juarez-PTY Panama City Tocumen Intl
11h 15m2 stops Medellín Jose Maria Cordova Intl Bogotá El Dorado
Avianca Logo
02:30 - 12:15PTY  Panama City Tocumen Intl-MEX Mexico City Benito Juarez
10h 45m1 stop Bogotá El Dorado
£327Avianca
Booking Insights

Price, demand, and travel trends for Mexico City to Panama City flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights from Mexico City to Panama City with more confidence.

How much is a return flight from Mexico City to Panama City?

Return flights from Mexico City to Panama City start at £273. Prices are typical for this route right now, with typical return fares ranging from £260 to £382. The lowest price found in the past 5 days was £273 on Avianca.

What's the cheapest day of the week to fly from Mexico City to Panama City?

Thursday is the cheapest day of the week to fly from Mexico City to Panama City and is 4% cheaper than the average day. Monday is the most expensive day with flight prices 8% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Mexico City to Panama City?

•January is the cheapest month to fly from Mexico City to Panama City at £276 return.
•July (£338) and April (£327) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 22% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Mexico City to Panama City the cheapest?

Flights from Mexico City to Panama City are cheapest 6 weeks before departure. Booking in this window typically costs about 27% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Expert advice

Expert advice for your flight from Mexico City to Panama City

 
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on MEX

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Key details for Mexico City to Panama City flights

Low season

May

Cheapest flight

£137
Most popular time to fly and prices are also 3% lower on average.
Flights from Mexico City to Panama City

When to book flights from Mexico City to Panama City

Are your dates flexible? Find out the best times to travel from Mexico City to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Mexico City to Panama City flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines, and booking questions.

  • What are the earliest and latest flights from Mexico City to Panama City?

    These are the earliest and latest flight times available from Mexico City to Panama City:

    • Earliest: departs at 00:25 and lands at 04:13
    • Latest: departs at 15:30 and lands at 19:18.

    The flight takes about 3h 48m.

  • Which cabin classes can I book on flights from Mexico City to Panama City?

    Only Economy class is available on flights from Mexico City to Panama City.

  • How long is a flight from Mexico City to Panama City?

    A direct flight from Mexico City to Panama City takes 3h 48m, covering 1,497 miles.

  • Do I need a passport to fly from Mexico City to Panama City?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Mexico City to Panama City flight?

    Return flights from Mexico City to Panama City range from £260 to £382, with an average of £302 over the past 12 months. Anything below £260 counts as a good deal.

  • How expensive are last-minute Mexico City to Panama City flights?

    Last-minute fares on this route (booked within 2 weeks of departure) run 24% above the route average of £302. Book 6 weeks before departure for the lowest fares.

  • How much can I save by having a stopover when flying from Mexico City to Panama City?

    On this route, direct and stopover fares are close on average, with direct at £306 return and stopover options via Bogotá El Dorado (BOG) at £294.

  • How does Copa Airlines's on-time performance compare to other airlines on Mexico City to Panama City flights?

    Copa Airlines is slightly above the route average for timely arrivals, while AeroMexico Connect has a lower on-time arrival rate. On-time arrival rates on Mexico City to Panama City flights are:

    • Copa Airlines: 96% on time
    • AeroMexico Connect: 95% on time
    • Aeromexico: 92% on time

    On average, flights on this route are punctual 96% of the time.

  • What is the standard checked bag allowance on flights from Mexico City to Panama City?

    There is no standard. Checked bag policies vary by airline on this route. Most carriers charge £45–£75 for the first checked bag in Economy. Premium fares and elite status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from Mexico City to Panama City?

    The Boeing 737 MAX 8 family is used most often on this route, operated mainly by Aeromexico and Copa Airlines. Other aircraft seen on the route include Boeing 737-800 variants.

  • How are flight departures from Mexico City to Panama City spread across the day?

    Morning is the busiest departure period on Mexico City to Panama City flights, with 43% leaving in that window. Afternoon departures account for 29%, Night flights for 28%, and Evening flights for 0%.

  • Have flight prices from Mexico City to Panama City changed much recently?

    Yes. Based on fares seen in the past 5 days, return flight prices on this route showed a wide range, from about £273 to £1,519. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Mexico City to Panama City looking right now?

    One-way fares from Mexico City to Panama City are currently higher than usual. Average one-way flight prices are about £421, which is 103% above the typical average for this route.

  • Which car hire options are available at Panama City Tocumen Intl Airport (PTY)?

    Panama City Tocumen Intl Airport (PTY) hosts 5 major car hire companies, with daily rates starting from around £1 for economy cars. Top options include:
    • Avis
    • Europcar
    • Ace
    • Budget
    • Hertz

  • Which airports can I use when flying from Mexico City to Panama City?

    Flights from Mexico City to Panama City usually depart from Mexico City Benito Juarez (MEX) and arrive at Panama City Tocumen Intl (PTY).

  • How do delay rates compare for morning and evening flights from Mexico City to Panama City?

    Night flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

  • At what point is a flight considered delayed on the route from Mexico City to Panama City?

    A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Mexico City to Panama City route, 4% of flights were delayed in the past 3 months, with delays averaging 2 hours 26 minutes.

  • Which airports do connecting flights from Mexico City to Panama City pass through?

    One-stop flights from Mexico City to Panama City most commonly connect through:

    • Bogotá El Dorado (BOG) – 51% of one-stop connections
    • San Salvador El Salvador Intl (SAL) – 48% of one-stop connections
    • Monterrey Gen Mariano Escobedo (MTY) – 0% of one-stop connections

    Bogotá El Dorado (BOG) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Mexico City to Panama City?

    Yes. Being flexible with your travel dates can save you up to 11% on the Mexico City to Panama City route. Thursday is the cheapest departure day at £291 return on average, while Monday is the most expensive at £327, a difference of £36. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • Which airlines are available on the route from Mexico City to Panama City?

    2 airlines operate flights between Mexico City and Panama City. The airlines offering direct flights on this route include:

    • Copa Airlines
    • Aeromexico

  • How much time can I save by choosing a different stopover airport from Mexico City to Panama City?

    Flying via San Salvador El Salvador Intl (SAL) gives the shortest average 1-stop total travel time of 6h 59m, compared to 9h 35m via Bogotá El Dorado (BOG) and 11h 10m via Monterrey Gen Mariano Escobedo (MTY).

  • What is the time difference between Mexico City and Panama City?

    Panama City is 1 hour ahead of Mexico City (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • Which airlines offer extra legroom and free seat selection on Mexico City to Panama City flights?

    Among airlines operating Mexico City to Panama City flights:

    • Aeromexico: offers free seat selection
    • Copa Airlines: offers extra legroom; offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines include bags at no extra cost on Mexico City to Panama City flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • Aeromexico: a cabin bag and a checked bag in Economy class
    • Copa Airlines: a cabin bag and a checked bag in Economy class
    • AeroMexico Connect: a cabin bag in Economy class class

    Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.

  • Which airlines offer an eco-friendly journey on the Mexico City to Panama City route?

    Avianca Airlines is one of the airlines committed to offsetting carbon emissions by ensuring a 13% carbon reduction per passenger. This airline also collaborates with passengers to ensure a clean environment through voluntary contributions to reduce waste and conserve forest ecosystems. American Airlines also offers sustainable travel and is committed to attaining net-zero carbon emissions by recycling aluminum and using sustainable aviation fuel.

  • Are there allowances to upgrade to first class on flights from Mexico City to Panama City?

    You can upgrade to first class if you need a smooth journey on the Mexico City to Panama City route. Your airline can email you about the availability of seats and the amount you need to pay. The advantage of upgrading instead of originally booking a first class ticket is that it’s cheaper. The amount you pay depends on your airline and class fare. Also, most airlines require you to upgrade at least 24 hours before takeoff.

  • Which nearby cities are served by Panama Tocumen International Airport (PTY)?

    After arriving at PTY airport, you can visit a few nearby cities, including Cabra to the northeast, Cerro Azul to the north, La Cabima to the northwest, Ancon to the west, and Balboa to the southwest. You can get to your destination by using public transportation outside the airport or enjoying the flexibility of a rental car.

  • Are the origin and destination airports hubs for any airlines?

    Benito Juarez International Airport is a hub for Volaris, Interjet, and Aeromexico. This airport serves thousands of passengers daily, linking many domestic and international cities. At the same time, Panama Tocumen International Airport is a hub for Copa Airlines. This airport serves many North American, South American, and Caribbean cities.

Your guide to booking Mexico City to Panama City flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure instead of Monday. On this route, Thursday flights average £291 – about £36 less than Monday (11% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 6 weeks before you fly. On this route, that window historically saves about 27% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Mexico City to Panama City trip for January. Fares historically average £276 return in that month – typically £62 less than the most expensive month, which is July (based on the last 12 months).
  • If arriving on time is high on your priority list, Copa Airlines is the strongest pick on this route. 96% of Copa Airlines flights from Mexico City to Panama City arrived on time in the past 3 months, slightly above the route's average on-time arrival rate of 96%. When flights on this route do arrive late, the average delay is 2 hours26 minutes, so choosing an airline with strong on-time performance can make a difference on tight schedules.
  • If you have the time, taking a 1-stop flight through Bogotá El Dorado Airport (BOG) can be cheaper than flying direct. The cheapest stopover option averages £294 return on this route – about £11 less than direct flights (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City Tocumen Intl Airport.
    - Riande Aeropuerto Hotel & Casino
  • Copa Airlines provide special dietary options to travelers with medical, dietary, or religious needs on the Mexico City (MEX) to Panama City (PTY) route. However, you need to order at least 24 hours before departure by contacting the airline’s call center.
  • The carry-on and checked luggage allowance on cheap flights from Mexico City to Panama City varies from one airline to another. If you book American Airlines, your carry-on luggage shouldn't exceed 22 x 14 x 9 inches, and you can bring an additional checked bag weighing no more than 50 lbs.
  • Benito Juarez International Airport (MEX) is wheelchair accessible to ensure a smooth journey for passengers with limited mobility. The airport offers free transfer to travelers with disabilities and has accessible toilets and elevators.
  • Business class amenities to enjoy on cheap flights from Mexico City to Panama City include priority check-in, lounge access, additional luggage allowance, large legroom, luxury dining, and in-flight entertainment. However, some amenities depend on your airline.
  • One way to travel to MEX airport from downtown Mexico City is to take the Line 4 bus to arrive there in about 5 minutes. Another option is the Line 1 subway, which gets you to the airport in approximately 4 minutes. If you have a piece of heavy luggage, you can take a taxi to arrive in around 6 minutes.

Prefer to fly direct from Mexico City to Panama City?

 
Find which airlines fly direct from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Mexico City Benito Juarez to Panama City Tocumen Intl

Monday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Tuesday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Wednesday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Thursday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Friday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Saturday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Sunday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Mexico City Benito Juarez

Monday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Tuesday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Wednesday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Thursday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Friday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Saturday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

Sunday

Aeromexico,Copa Airlines

Aeromexico,Copa Airlines

See more direct flights

More options for your flight from Mexico City to Panama City

Complete your trip to Panama City with a hotel stay or car hire