MEX - SCL

£263 Find Cheap Flights from Mexico City to Santiago – Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest return flight
£513
Typical prices: £439-£613
Copa Airlines
Sat 3/11Sun 11/11
MEX - SCL • 1 stop
Cheapest direct flights
£781
Typical prices: £434-£645
LATAM Airlines
Thu 20/9Thu 1/11
MEX - SCL • Direct
Direct flights
You can fly direct with LATAM Airlines and Aeromexico. Average duration is 8h 28m
Direct flights
+1
Direct flights
+1
Avoid delays
Most punctual • 92% on-time
Best time • Fewest delays
Insights
Insights
When to book
in advance
Our data shows that travellers who book at least 9 weeks in advance save around 20% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 13% price drop
Most popular
Good to know
+1
Good to know
+1
Top stopover airports
Cheapest • Avg £481 (return)
Shortest trip • 13h 24m (one-way)
Insights
Insights
Start a new search
KAYAK searches hundreds of sites at once to find you the best travel deals.
We hope you enjoy your trip to Santiago!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Mexico City to Santiago (MEX-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Mexico City to Santiago

Tue, 3 Nov - Wed, 11 Nov
Copa Airlines Logo
02:00 - 23:36MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
18h 36m1 stop Panama City Tocumen Intl
Copa Airlines Logo
03:19 - 22:05SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
21h 46m1 stop Panama City Tocumen Intl
£513Copa Airlines
Sat, 3 Oct - Wed, 7 Oct
Copa Airlines Logo
00:25 - 23:39MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
20h 14m1 stop Panama City Tocumen Intl
Copa Airlines Logo
05:22 - 19:05SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
16h 43m1 stop Panama City Tocumen Intl
£522Copa Airlines
Sat, 3 Oct - Sat, 10 Oct
Multiple Airlines Logo
22:00 - 22:10MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
21h 10m1 stop Cancun
Multiple Airlines Logo
09:30 - 15:45SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
9h 15mdirect
£558Multiple Airlines
Thu, 1 Oct - Thu, 8 Oct
Copa Airlines Logo
05:50 - 00:22MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
15h 32m1 stop Panama City Tocumen Intl
Copa Airlines Logo
05:22 - 00:15SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
21h 53m1 stop Panama City Tocumen Intl
£567Copa Airlines
Sat, 3 Oct - Sat, 10 Oct
Multiple Airlines Logo
22:00 - 22:10MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
21h 10m1 stop Cancun
Multiple Airlines Logo
05:10 - 13:50SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
11h 40m1 stop Lima J Chavez Intl
£569Multiple Airlines
Sat, 3 Oct - Sun, 11 Oct
Multiple Airlines Logo
22:00 - 22:10MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
21h 10m1 stop Cancun
Multiple Airlines Logo
09:30 - 15:45SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
9h 15mdirect
£577Multiple Airlines
Thu, 8 Oct - Fri, 23 Oct
Copa Airlines Logo
02:10 - 03:56MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
22h 46m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:23 - 01:00SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
15h 37m1 stop Panama City Tocumen Intl
£578Copa Airlines
Sun, 4 Oct - Tue, 6 Oct
Multiple Airlines Logo
06:45 - 04:55MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
19h 10m2 stops Cancun Punta Cana
Multiple Airlines Logo
01:07 - 12:10SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
14h 03m1 stop Panama City Tocumen Intl
£580Multiple Airlines
Sat, 3 Oct - Sat, 10 Oct
Multiple Airlines Logo
22:00 - 22:10MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
21h 10m1 stop Cancun
Multiple Airlines Logo
09:30 - 15:45SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
9h 15mdirect
£581Multiple Airlines
Sat, 26 Sep - Sat, 3 Oct
Multiple Airlines Logo
22:00 - 22:10MEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
21h 10m1 stop Cancun
Multiple Airlines Logo
09:30 - 15:45SCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
9h 15mdirect
£583Multiple Airlines
Booking Insights

Price, demand, and travel trends for Mexico City to Santiago flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights from Mexico City to Santiago with more confidence.

How much is a return flight from Mexico City to Santiago?

Return flights from Mexico City to Santiago start at £513. Prices are typical for this route right now, with typical return fares ranging from £439 to £613. The lowest price found in the past 5 days was £513 on Copa Airlines.

What's the cheapest day of the week to fly from Mexico City to Santiago?

Monday is the cheapest day of the week to fly from Mexico City to Santiago and is 3% cheaper than the average day. Saturday is the most expensive day with flight prices 6% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Mexico City to Santiago?

  • January is the cheapest month to fly from Mexico City to Santiago at £455 return.
  • July (£577) and June (£570) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 26% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Mexico City to Santiago the cheapest?

Flights from Mexico City to Santiago are cheapest 9 weeks before departure. Booking in this window typically costs about 20% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Expert advice

Expert advice for your flight from Mexico City to Santiago

 
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on LATAM Airlines and Aeromexico

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialising in airline interiors and regulations. 10 years ago, she pivoted to journalism. She shares her insights in leading aviation, travel and business publications and on her site, FlightChic.

Key details for Mexico City to Santiago flights

Low season

May

Cheapest flight

£263
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly and prices are also 11% lower on average.
Flights from Mexico City to Santiago

When to book flights from Mexico City to Santiago

Are your dates flexible? Find out the best times to travel from Mexico City to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Mexico City to Santiago flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines, and booking questions.

  • Which airlines offer extra legroom and free seat selection on Mexico City to Santiago flights?

    Among airlines operating Mexico City to Santiago flights:

    • LATAM Airlines: offers extra legroom; offers free seat selection
    • Aeromexico: offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines are available on the route from Mexico City to Santiago?

    2 airlines operate flights between Mexico City and Santiago. The airlines offering direct flights on this route include:

    • LATAM Airlines
    • Aeromexico

  • Which airports can I use when flying from Mexico City to Santiago?

    Flights from Mexico City to Santiago usually depart from Mexico City Benito Juarez (MEX) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airlines include bags at no extra cost on Mexico City to Santiago flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • LATAM Airlines: a cabin bag and a checked bag in Economy class
    • Aeromexico: a cabin bag and a checked bag in Economy class
    • AeroMexico Connect: a cabin bag in Economy class class

    Bag allowance can vary by ticket type, cabin class, route, and airline, so travellers should check the fare details before booking.

  • Which cabin classes can I book on flights from Mexico City to Santiago?

    Only Economy class is available on flights from Mexico City to Santiago.

  • How much can I save by having a stopover when flying from Mexico City to Santiago?

    On this route, stopover flights are cheaper than direct options on average. Stopover fares average £481 return via Lima J Chavez Intl (LIM), compared with £543 for direct.

  • What is the standard checked bag allowance on flights from Mexico City to Santiago?

    There is no standard. Checked bag policies vary by airline on this route. Most carriers charge £43–£74 for the first checked bag in Economy. Premium fares and elite status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from Mexico City to Santiago?

    The Airbus A330 family is used most often on this route, operated mainly by LATAM Airlines and Aerolineas Argentinas. Other aircraft seen on the route include Boeing 787-9 Dreamliner variants.

  • Which airports do connecting flights from Mexico City to Santiago pass through?

    One-stop flights from Mexico City to Santiago most commonly connect through:

    • Bogotá El Dorado (BOG) – 64% of one-stop connections
    • Panama City Tocumen Intl (PTY) – 29% of one-stop connections
    • Lima J Chavez Intl (LIM) – 7% of one-stop connections

    Bogotá El Dorado (BOG) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Mexico City to Santiago?

    Yes. Being flexible with your travel dates can save you up to 9% on the Mexico City to Santiago route. Monday is the cheapest departure day at £508 return on average, while Saturday is the most expensive at £556, a difference of £48. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • At what point is a flight considered delayed on the route from Mexico City to Santiago?

    A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Mexico City to Santiago route, 8% of flights were delayed in the past 3 months, with delays averaging 3 hours 1 minute.

  • How are flight departures from Mexico City to Santiago spread across the day?

    Evening is the busiest departure period on Mexico City to Santiago flights, with 100% leaving in that window. Morning departures account for 0%, Afternoon flights for 0%, and Night flights for 0%.

  • What popular places can I visit in Santiago?

    Museum of Contemporary Art is one of the most viewed places in Santiago on KAYAK.

  • What are the earliest and latest flights from Mexico City to Santiago?

    These are the earliest and latest flight times available from Mexico City to Santiago:

    • Earliest: departs at 09:55 and lands at 18:23
    • Latest: departs at 20:05 and lands at 04:33.

    The flight takes about 8h 28m.

  • How expensive are last-minute Mexico City to Santiago flights?

    Last-minute fares on this route (booked within 2 weeks of departure) run 9% above the route average of £524. Book 9 weeks before departure for the lowest fares.

  • How long is a flight from Mexico City to Santiago?

    A direct flight from Mexico City to Santiago takes 8h 28m, covering 4,096 miles.

  • Do I need a passport to fly from Mexico City to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How are flight prices from Mexico City to Santiago looking right now?

    One-way fares from Mexico City to Santiago are currently higher than usual. Average one-way flight prices are about £823, which is 197% above the typical average for this route.

  • How does Aeromexico's on-time performance compare to other airlines on Mexico City to Santiago flights?

    Aeromexico is the only airline operating Mexico City to Santiago flights. 92% of its flights are on time.

  • How do delay rates compare for morning and evening flights from Mexico City to Santiago?

    Morning flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

  • How much time can I save by choosing a different stopover airport from Mexico City to Santiago?

    Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time of 13h 24m, compared to 13h 31m via Bogotá El Dorado (BOG) and 17h 35m via Lima J Chavez Intl (LIM).

  • What is the time difference between Mexico City and Santiago?

    Santiago is 3 hours ahead of Mexico City (Chile Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • Which car hire options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car hire companies, with daily rates starting from around £4 for economy cars. Top options include:
    · Lucano
    · United Rent-A-Car
    · Rosselot
    · FlexWays
    · Alamo

  • How much should I expect to pay for a Mexico City to Santiago flight?

    Return flights from Mexico City to Santiago range from £439 to £613, with an average of £524 over the past 12 months. Anything below £439 counts as a good deal.

Your guide to booking Mexico City to Santiago flights

Get tips on when to book, when to fly, and what to know before your trip.
  • If your dates are flexible, aim for a Monday departure instead of Saturday. On this route, Monday flights average £508 – about £48 less than Saturday (9% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 9 weeks before you fly. On this route, that window historically saves about 20% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Mexico City to Santiago trip for January. Fares historically average £455 return in that month – typically £122 less than the most expensive month, which is July (based on the last 12 months).
  • If you have the time, taking a 1-stop flight through Lima J Chavez Intl Airport (LIM) can be cheaper than flying direct. The cheapest stopover option averages £481 return on this route – about £62 less than direct flights (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.
    - Holiday Inn Santiago - Airport Terminal By IHG

Prefer to fly direct from Mexico City to Santiago?

 
Find which airlines fly direct from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Mexico City Benito Juarez to Santiago Arturo Merino Benitez

Monday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Tuesday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Wednesday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Thursday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Friday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Saturday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Sunday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Mexico City Benito Juarez

Monday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Tuesday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Wednesday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Thursday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Friday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Saturday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Sunday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

See more direct flights

More options for your flight from Mexico City to Santiago

Complete your trip to Santiago with a hotel stay or car hire