Find cheap flights from Prague to Chicago from £435

In the last 3 days, the lowest price for a flight from Prague to Chicago O'Hare Intl Airport was £545 for a one-way ticket and £615 for a return.

We unfortunately don’t have that data for this specific route.

Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Prague and Chicago, with Star Alliance being the most commonly used for this route.

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Prague to Chicago.

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from Prague is likely to change within 7 days, so travellers know whether to wait or book now.

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Chicago with an airline and back to Prague with another airline.

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from Prague up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.