SOU - STL

£847 Find Cheap Flights from Southampton to St. Louis – Compare and Save

1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Southampton to St. Louis (SOU-STL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Southampton to St. Louis

Fri, 4 Dec - Fri, 11 Dec
Virgin Atlantic Logo
17:35 - 16:24SOU  Southampton Eastleigh-STL Lambert-St Louis
28h 49m2 stops Amsterdam Schiphol Atlanta Hartsfield-Jackson
Virgin Atlantic Logo
17:31 - 08:55STL  Lambert-St Louis-SOU Southampton Eastleigh
33h 24m2 stops Atlanta Hartsfield-Jackson Amsterdam Schiphol
£847Virgin Atlantic
Fri, 4 Dec - Fri, 11 Dec
Multiple Airlines Logo
09:20 - 22:17SOU  Southampton Eastleigh-STL Lambert-St Louis
18h 57m3 stops Dublin London Heathrow Chicago O'Hare Intl
Multiple Airlines Logo
11:37 - 08:45STL  Lambert-St Louis-SOU Southampton Eastleigh
15h 08m2 stops Chicago O'Hare Intl Dublin
£942Multiple Airlines
Fri, 4 Dec - Fri, 11 Dec
Multiple Airlines Logo
12:25 - 00:12SOU  Southampton Eastleigh-STL Lambert-St Louis
41h 47m3 stops Dublin Lisbon Humberto Delgado Orlando
Multiple Airlines Logo
17:38 - 08:55STL  Lambert-St Louis-SOU Southampton Eastleigh
33h 17m3 stops Chicago O'Hare Intl Dublin Amsterdam Schiphol
£1,166Multiple Airlines
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Price, demand, and travel trends for Southampton to St. Louis flights

Use KAYAK data on prices, travel dates, airlines, and seasonal trends to compare options and book flights with more confidence.

Which airline is the cheapest to fly from Southampton to St. Louis?

Virgin Atlantic (£847) offered the cheapest return ticket from Southampton to St. Louis in the last 5 days.

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Key details for Southampton to St. Louis flights

Cheapest flight

£847
Round-trip flight from Southampton to St. Louis

When to book flights from Southampton to St. Louis

Are your dates flexible? Find out the best times to travel from Southampton to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price

Your Southampton to St. Louis flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines, and booking tips.

  • Do I need a passport to fly from Southampton to St. Louis?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Southampton to St. Louis changed much recently?

    Yes. Based on fares seen in the past 5 days, return prices on this route varied from about £847 to £1,166. That means the highest observed fare was about 37% higher than the lowest one.

  • Which car hire options are available at Lambert-St Louis Airport (STL)?

    Lambert-St Louis Airport (STL) hosts 5 major car hire companies, with daily rates starting from around £23 for economy cars. Top options include:

    • Hertz
    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Payless

  • Which airports can I use when flying from Southampton to St. Louis?

    Flights from Southampton to St. Louis usually depart from Southampton Eastleigh (SOU) and arrive at Lambert-St Louis (STL).

  • What is the time difference between Southampton and St. Louis?

    St. Louis is 5 hours behind Southampton (Central Time vs British Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in St. Louis?

    Some of the most popular sights in St. Louis are St. Louis Union Station, Gateway Arch, and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

Your guide to booking Southampton to St. Louis flights

Get tips on when to book, when to fly, and what to know before your trip.

More options for your flight from Southampton to St. Louis

Complete your trip to St. Louis with a hotel stay or car hire

Car hire in St. Louis
Hotels in St. Louis
Holidays in St. Louis