SOU - SCL

£1,062 Find Cheap Flights from Southampton to Santiago – Compare and Save

This is the cheapest return flight price found by a KAYAK user in the last 72 hours by searching for a flight from Southampton to Santiago departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Southampton to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Southampton to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest return fare
£1,062
Delta
Sun 8/11Wed 25/11
SOU - SCL • 2 stops
Cheapest one-way flight
£2,386
Delta
Wed 22/7
SOU - SCL • 2 stops
Direct flights
Not available
There are currently no direct flights between Southampton and Santiago. You’ll need at least 2 connections.
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We hope you love your trip to Santiago!
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Flight Deals

Cheap Flights from Southampton to Santiago (SOU-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for return flights from Southampton to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent return flight deals from Southampton to Santiago

Sun, 8 Nov - Wed, 25 Nov
Delta Logo
17:30 - 07:40
SOU
-
SCL
65h 10m
2 stops
Delta Logo
23:10 - 17:00
SCL
-
SOU
38h 50m
2 stops
£1,062Delta
Wed, 4 Nov - Mon, 30 Nov
Delta Logo
17:30 - 07:40
SOU
-
SCL
41h 10m
2 stops
Delta Logo
23:10 - 08:10
SCL
-
SOU
30h 00m
2 stops
£1,112Delta
Mon, 9 Nov - Fri, 27 Nov
Delta Logo
08:40 - 07:40
SOU
-
SCL
50h 00m
2 stops
Delta Logo
23:10 - 08:55
SCL
-
SOU
30h 45m
2 stops
£1,162Delta
Wed, 4 Nov - Tue, 1 Dec
Delta Logo
17:30 - 07:40
SOU
-
SCL
41h 10m
2 stops
Delta Logo
23:10 - 08:10
SCL
-
SOU
54h 00m
2 stops
£1,212Delta
Wed, 12 Aug - Sat, 7 Nov
Delta Logo
18:05 - 07:15
SOU
-
SCL
42h 10m
2 stops
Delta Logo
23:10 - 08:10
SCL
-
SOU
54h 00m
2 stops
£1,218Delta
Fri, 6 Nov - Mon, 30 Nov
Delta Logo
08:40 - 07:40
SOU
-
SCL
26h 00m
2 stops
Delta Logo
23:10 - 08:10
SCL
-
SOU
30h 00m
2 stops
£1,236Delta
Thu, 5 Nov - Wed, 25 Nov
Delta Logo
17:30 - 07:40
SOU
-
SCL
41h 10m
2 stops
Delta Logo
23:10 - 17:00
SCL
-
SOU
38h 50m
2 stops
£1,237Delta
Wed, 4 Nov - Sun, 29 Nov
Delta Logo
17:30 - 07:40
SOU
-
SCL
41h 10m
2 stops
Delta Logo
23:10 - 08:10
SCL
-
SOU
54h 00m
2 stops
£1,262Delta
Thu, 13 Aug - Sat, 7 Nov
Delta Logo
09:15 - 07:15
SOU
-
SCL
27h 00m
2 stops
Delta Logo
23:10 - 08:10
SCL
-
SOU
54h 00m
2 stops
£1,268Delta
Mon, 10 Aug - Fri, 6 Nov
Delta Logo
18:05 - 07:15
SOU
-
SCL
42h 10m
2 stops
Delta Logo
23:10 - 08:55
SCL
-
SOU
30h 45m
2 stops
£1,368Delta
Booking Insights

Good to know - Cheap tickets from Southampton to Santiago

Cheapest flight£1,062
Flight from Southampton to Santiago

When to book flights from Southampton to Santiago

Are your dates flexible? Find out the best times to travel from Southampton to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated return price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or returns with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Southampton to Santiago

  • What is the cheapest flight from Southampton to Santiago?

    In the last 3 days, the lowest price for a flight from Southampton to Santiago was £2,386 for a one-way ticket and £1,062 for a return.

  • Which airports will I be using when flying from Southampton to Santiago?

    Southampton airport is called Southampton Eastleigh and the only airport in Santiago is Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Southampton to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Southampton to Santiago?

    SkyTeam is the only airline alliance operating flights between Southampton and Santiago.

  • How does KAYAK find such low prices on flights from Southampton to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Southampton to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Southampton to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Southampton is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Southampton to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional return ticket. You could then fly to Santiago with an airline and back to Southampton with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Southampton to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Southampton up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Southampton to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Southampton to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Southampton to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
KLMOverall score based on 1530 reviews
7.3Food
7.8Boarding
7.2Entertainment
8.4Crew
7.7Comfort
Airline reviews

The flight was 45 mins late leaving, we sat without a/c for some of this, 2nd Meal was a slice of pizza. Movies were good.

8.0 ExcellentAnonymous, Jun 2026
LHR - AMS
Read more KLM reviews

The flight was 45 mins late leaving, we sat without a/c for some of this, 2nd Meal was a slice of pizza. Movies were good.

As always, it’s a pleasure to travel with KLM. It is one of my favorite airlines.

Brand new plane lots of room the snack was very flavourful and enjoyable

There were no charge points for phones on the economy seats. The seats were comfortable overall. Food was okay.. flight was on time

It was really nice journey i personally recommend klm flight

Empty seats next to me - wish it had been for a longer flight!!

I’m grateful for the KLM Air France shuttle bus service to Ottawa. However due to construction and other issues related to the chaotic Uber pickup system at YUL, it’s a challenge to find the Kelios bus service to Ottawa. The signs are not clear or even available. No staff to guide passengers. It’s a stressful experience.

Flight was on time, staff are friendly and helpful onboard.

Terrible last row seats many seats available but no offer to move to better seat

Delay and had to run between flight to get my connection due to this delay but besides that the overall experience was ok. I arrived with just an hour of delay.

Everything you need to know for your flight from Southampton to Santiago

Information on your arrival and departure airports